CAS 306-07-0

Cloridrato di pargilina

Descrizione:

Cloridrato di pargilina è un composto farmaceutico riconosciuto principalmente per il suo ruolo come inibitore della monoamino ossidasi (IMAO). È comunemente usato nel trattamento di alcuni tipi di depressione ed è stato studiato per le sue proprietà neuroprotettive. La sostanza appare come una polvere cristallina bianca a bianco sporco ed è solubile in acqua, il che facilita la sua somministrazione in contesti clinici. La pargilina agisce inibendo l'enzima monoamino ossidasi, aumentando così i livelli di neurotrasmettitori come serotonina, norepinefrina e dopamina nel cervello, il che può aiutare ad alleviare i sintomi depressivi. La sua struttura chimica include un anello di piridina, contribuendo alla sua attività farmacologica. Sebbene sia efficace, l'uso di Cloridrato di pargilina richiede un attento monitoraggio a causa delle potenziali restrizioni dietetiche e delle interazioni con altri farmaci, in particolare quelli contenenti tiramina, che possono portare a crisi ipertensive. Come con qualsiasi IMAO, i pazienti devono essere informati sui rischi e benefici associati al suo uso.

Formula: C₁₁H₁₄ClN

InChI: InChI=1/C11H13N.ClH/c1-3-9-12(2)10-11-7-5-4-6-8-11;/h1,4-8H,9-10H2,2H3;1H

InChI key: InChIKey=BCXCABRDBBWWGY-UHFFFAOYSA-N

SMILES: C(N(CC#C)C)C1=CC=CC=C1.Cl

Sinonimi:

• A 19120
• Benzenemethanamine, N-methyl-N-2-propyn-1-yl-, hydrochloride (1:1)
• Benzenemethanamine, N-methyl-N-2-propynyl-, hydrochloride
• Benzylamine, N-methyl-N-2-propynyl-, hydrochloride
• Eutonyl
• Eutonyl-ten
• Methylbenzylpropynylamine hydrochloride
• Mo 911
• N-Benzyl-N-methyl-2-propynylamine hydrochloride
• N-Methyl-N-(2-propynyl)benzylamine hydrochloride
• N-Methyl-N-2-propynylbenzylamine hydrochloride
• N-benzyl-N-methylprop-2-yn-1-amine
• N-benzyl-N-methylprop-2-yn-1-amine hydrochloride (1:1)
• N-methyl-N-propargylbenzylamine hydro-chloride
• NSC 43798
• Parguline HCL
• Pargyline Hcl
• n-methyl-n-2-propynyl-benzylaminhydrochloride
• PARGYLINE HYDROCHLOR
• PARGYLINE HYDROCHLORIDE MAO INHIBITOR
• N-METHYL-N-PROPARGYLBENZYLAMINE HYDROCHLORIDE
• benzylmethylpropynylaminehydrochloride
• N-methyl-N-(phenylmethyl)-2-propyn-1-amine hydrochloride
• n-benzyl-n-methyl-2-propynylaminhydrochloride
• N-Methyl-npropargylbenzeneMethanaMine HCl
• n-benzyl-n-methyl-2-propynylaminehydrochloride
• N-METHYL-N-(2-PROPYNY)BENZYLAMINE HYDROCHLORIDE
• N-benzyl-N-methylprop-2-yn-1-amine hydrochloride
• N-methyl-N-(phenylmethyl)prop-2-yn-1-amine hydrochloride
• Pargyline Hydrochloride (200 mg)
• PARGYLINE HYDROCHLORIDE USP/EP/BP
• PARGYLINE HYDROCHLORIDE
• pargylinechloride
• benzyl-methyl-propargyl-amine hydrochloride
• N-Methyl-N-(2-propynyl)benzylamine hydrochloride, N-Methyl-N-propargylbenzylamine hydrochloride
• Pargyline hydrochloride,N-Methyl-N-(2-propynyl)benzylamine hydrochloride, N-Methyl-N-propargylbenzylamine hydrochloride
• Pargylamine hydrochloride

Pargyline Hydrochloride

CAS: 306-07-0

Colore e forma: Neat

Ref: 61-FOR1912.00

Pargyline, HCl

CAS: 306-07-0

Formula: C₁₁H₁₄ClN

Purezza: 99%

Colore e forma: Solid

Peso molecolare: 195.6886

Ref: IN-DA0030N6

Pargyline hydrochloride

CAS: 306-07-0

Pargyline hydrochloride (Pargylamine hydrochloride) is an irreversible monoamine oxidase(MAO) inhibitor with antihypertensive properties.

Formula: C₁₁H₁₄ClN

Purezza: 99.41% - 99.91%

Colore e forma: Solid

Peso molecolare: 195.69

Ref: TM-T1578

Pargyline hydrochloride

CAS: 306-07-0

Pargyline hydrochloride

Purezza: ≥98%

Peso molecolare: 195.69g/mol

Ref: 54-BUP17536

Pargyline hydrochloride

CAS: 306-07-0

Pargyline hydrochloride

Purezza: 98%

Colore e forma: Solid

Peso molecolare: 195.69g/mol

Ref: 54-OR54425

Pargyline hydrochloride

CAS: 306-07-0

Formula: C₁₁H₁₃N·HCl

Purezza: ≥ 98.0%

Colore e forma: White to off-white crystalline powder

Peso molecolare: 195.69

Ref: 7W-GP7491

Pargyline Hydrochloride

Prodotto controllato

CAS: 306-07-0

Formula: C₁₁H₁₃N·ClH

Colore e forma: Neat

Peso molecolare: 195.69

Ref: 86-MM1912.00

Pargyline Hydrochloride

Prodotto controllato

CAS: 306-07-0

Applications Pargyline Hydrochloride acts as a monoamine oxidase (MAO) inhibitor, decreasing systolic blood pressure steadily in subjects. Antihypertensive.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Fuentes, J. et al.: Eur. J. Pharm., 57, 21 (1979); Knoll, J. et al.: Tabei, R. et al.: Clin. Pharm. Ther., 11, 269 (1970);

Formula: C₁₁H₁₃N·ClH

Colore e forma: Neat

Peso molecolare: 195.69

Ref: TR-P193285

N-Benzyl-N-methylprop-2-yn-1-amine hydrochloride

CAS: 306-07-0

Formula: C₁₁H₁₄ClN

Purezza: 97%

Colore e forma: Solid

Peso molecolare: 195.69

Ref: 10-F336074

N-Methyl-N-propargylbenzylamine HCl

Prodotto controllato

CAS: 306-07-0

N-Methyl-N-propargylbenzylamine HCl is a nonsteroidal anti-inflammatory drug that inhibits the enzyme cyclooxygenase (COX) and blocks the production of prostaglandins. This drug has low potency, although its selectivity for COX-2 makes it an attractive candidate for treatment of inflammation associated with arthritis. N-Methyl-N-propargylbenzylamine HCl also has been shown to have receptor activity on toll-like receptor 4 in human biological samples. It has been shown to decrease dopamine levels in rats, suggesting that it may be a potential treatment for Parkinson's disease. In addition, this drug was found to decrease epithelial mesenchymal transition and increase expression of p53 protein in prostate cancer cells, as well as inhibit 5HT2 receptors in rat brain tissue. This drug also increases 5HT concentrations and decreases diastolic blood pressure in humans.

Purezza: Min. 95%

Ref: 3D-FM41823