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CAS 3064260-49-4

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  • COX-2-IN-51
    Targetmol
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    COX-2-IN-51

    CAS:
    <p>COX-2-IN-51 (E25) is a potent COX-2 inhibitor with an IC50 of 70.7 nM. It significantly suppresses LPS-induced release of NO and PGE2, the expression of COX-2 and iNOS, and the activation of the NF-κB pathway. Displaying anti-inflammatory and analgesic effects in various mouse models through NF-κB pathway inhibition, COX-2-IN-51 has lower gastrointestinal side effects compared to Indomethacin.</p>
    Formula:C23H18F4O3S
    Colore e forma:Solid
    Peso molecolare:450.446

    Ref: TM-T204857