CAS 32233-40-2

(3aR,4S,5R,6aS)-Esahidro-5-idrossi-4-(idrossimetil)-2H-ciclopenta[b]furano-2-one

Descrizione:

La sostanza chimica nota come (3aR,4S,5R,6aS)-Esahidro-5-idrossi-4-(idrossimetil)-2H-ciclopenta[b]furano-2-one, con il numero CAS 32233-40-2, è un composto biciclico caratterizzato dalla sua unica struttura ad anello fuso. Questo composto presenta più stereocentri, che contribuiscono alla sua specifica configurazione tridimensionale e possono influenzare la sua attività biologica. La presenza di gruppi idrossilici (-OH) indica che potrebbe presentare caratteristiche polari, migliorando la sua solubilità in acqua e la sua reattività in varie reazioni chimiche. Il gruppo furanone suggerisce che potrebbe partecipare a reazioni tipiche delle lattone e degli eteri ciclici, rendendolo di interesse nella sintesi organica e nella chimica medicinale. Inoltre, la stereochimica del composto potrebbe svolgere un ruolo cruciale nella sua interazione con obiettivi biologici, il che potrebbe essere rilevante per applicazioni farmacologiche. In generale, le caratteristiche strutturali di questo composto suggeriscono un'utilità potenziale in vari campi, incluso lo sviluppo di farmaci e la scienza dei materiali, sebbene applicazioni specifiche dipenderebbero da ulteriori ricerche e caratterizzazioni.

Formula: C₈H₁₂O₄

InChI: InChI=1/C8H12O4/c9-3-5-4-1-8(11)12-7(4)2-6(5)10/h4-7,9-10H,1-3H2/t4-,5-,6-,7+/m1/s1

InChI key: InChIKey=VYTZWRCSPHQSFX-GBNDHIKLSA-N

SMILES: C(O)[C@@H]1[C@@]2([C@](C[C@H]1O)(OC(=O)C2)[H])[H]

Sinonimi:

• (-)-6beta-Hydroxymethyl-7alpha-hydroxy-cis-2-oxabicyclo[3.3.0]octan-3-one
• (-)-Corey's lactone diol
• (-)-Coreydiol
• (3aR,4S,5R,6aS)-(-)-Hexahydro-5-hydroxy-4-(hydroxymethyl)-2H-cyclopenta[b]furan-2-one
• (3aR,4S,5R,6aS)-5-hydroxy-4-(hydroxymethyl)hexahydro-2H-cyclopenta[b]furan-2-one
• 2H-Cyclopenta[b]furan-2-one, hexahydro-5-hydroxy-4-(hydroxymethyl)-, [3aR-(3aα,4α,5β,6aα)]-
• 2H-Cyclopenta[b]furan-2-one, hexahydro-5-hydroxy-4-(hydroxymethyl)-, stereoisomer
• 2H-Cyclopenta[b]furan-2-one,hexahydro-5-hydroxy-4-(hydroxymethyl)-,(3aR,4S,5R,6aS)-
• Lactone diol
• (-)-Corey Lactone Diol
• (1R)-2β-(Hydroxymethyl)-3α,5α-dihydroxycyclopentane-1α-acetic acid 1,5-lactone
• (-)-COREY DIOL (COREY LACTONE)
• (1S,5R,6S,7R)-7-Hydroxy-6-hydroxymethyl-2-oxabicyclo[3.3.0]octan-3-one
• (3AR,4S,5R,6AS)-(-)-HEXAHYDRO-5-HYDROXY-4--2H-CYCLOPENTA(B)FURAN-2-ONE,
• (3aβ,4S,6aβ)-4β-(Hydroxymethyl)-5α-hydroxyhexahydro-2H-cyclopenta[b]furan-2-one
• (3AR,4S,5R,6AS)-(-)-HEXAHYDRO-5-HYDROXY-4-(HYDROXYMETHYL)-2H-CYCLOPENT A[B]FURAN-2-ONE
• Hexahydro-5-hydroxy-4-(hydroxymethyl)-2H-cyclopenta[b]furan-2-one.
• (3AR,4S,5R,6AS)-(-)-HEXAHYDRO-5-HYDROXY-4-HOCH2-2H-CYCLOPENTA(B)FURAN-2-ONE, 98%
• (-)-COREY LACTONE

(3aR,4S,5R,6aS)-(-)-Hexahydro-5-hydroxy-4-hydroxymethyl-2H-cyclopenta[b]furan-2-one, 98%

CAS: 32233-40-2

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Sci

Formula: C₈H₁₂O₄

Purezza: 98%

Peso molecolare: 172.18

Ref: 02-H56119

(3aR,4S,5R,6aS)-5-Hydroxy-4-(hydroxymethyl)hexahydro-2H-cyclopenta[b]furan-2-one

CAS: 32233-40-2

Formula: C₈H₁₂O₄

Purezza: 97%

Colore e forma: Solid

Peso molecolare: 172.1785

Ref: IN-DA0032AQ

(1S,5R,6S,7R)-(-)-7-Hydroxy-6-(hydroxymethyl)-2-oxabicyclo[3.3.0]octan-3-one

CAS: 32233-40-2

(1S,5R,6S,7R)-(-)-7-Hydroxy-6-(hydroxymethyl)-2-oxabicyclo[3.3.0]octan-3-one

Purezza: 99%

Colore e forma: Solid

Peso molecolare: 172.18g/mol

Ref: 54-OR52144

(-)-Corey lactone diol

CAS: 32233-40-2

(-)-Corey lactone diol

Purezza: ≥95%

Peso molecolare: 172.18g/mol

Ref: 54-BUP18578

(-)-Corey Lactone Diol

CAS: 32233-40-2

Formula: C₈H₁₂O₄

Purezza: >98.0%(GC)

Colore e forma: White to Almost white powder to crystal

Peso molecolare: 172.18

Ref: 3B-H1418

(-)-Corey lactone diol

CAS: 32233-40-2

(-)-Corey lactone diol is a pharmaceutical intermediate

Formula: C₈H₁₂O₄

Purezza: 98%

Colore e forma: White To Beige-Brown Cryst Powder Or Crystals

Peso molecolare: 172.18

Ref: TM-T8085

(3aR,4S,5R,6aS)-5-Hydroxy-4-(hydroxymethyl)hexahydro-2H-cyclopenta[b]furan-2-one

CAS: 32233-40-2

Formula: C₈H₁₂O₄

Purezza: 97%

Colore e forma: Solid

Peso molecolare: 172.18

Ref: 10-F239043

(-)-Corey Lactone Diol

Prodotto controllato

CAS: 32233-40-2

Applications (-)-Corey Lactone Diol is an intermediate of Iloprost (I267300) and shows inhibitory activity towards β-lactamase. Iloprost (I267300) is a synthetic analogue of Prostacyclin (PGI2) used to treat pulmonary arterial hypertension (PAH), scleroderma, Raynaud's phenomenon and ischemia.
References Gal, Z. et al.: J. Chemother., 12, 274 (2000); Zamudio, T.P.: Arch. Cardiol. Mex., 77, 198 (2007); Lai, Y. et al.: Am. J. Resp. Crit. Care Med., 178, 188 (2008);

Formula: C₈H₁₂O₄

Colore e forma: Neat

Peso molecolare: 172.18

Ref: TR-C694995

(-)-Corey lactone diol

CAS: 32233-40-2

(-)-Corey lactone diol is a synthetic compound that is soluble in organic solvents. It is used for the synthesis of carbocyclic nucleosides, which are analogs of pyrimidine nucleosides. (-)-Corey lactone diol has been shown to inhibit cholesterol synthesis and the synthesis of alkene. (-)-Corey lactone diol also shows anti-inflammatory properties, which may be due to its inhibition of prostaglandin synthesis.

Formula: C₈H₁₂O₄

Purezza: Min. 95%

Peso molecolare: 172.18 g/mol

Ref: 3D-FC29747