CAS 3226-65-1

Metionina solfossido

Descrizione:

Metionina solfossido è un derivato sulfoxide dell'aminoacido metionina, caratterizzato dalla presenza di un gruppo funzionale sulfoxide (–S(=O)–) attaccato all'atomo di zolfo della catena laterale della metionina. È un composto chirale, esistente in due forme enantiomeriche, che possono avere diverse attività biologiche. Metionina solfossido si forma spesso come risultato di stress ossidativo, dove le specie reattive dell'ossigeno ossidano i residui di metionina nelle proteine. Questa modifica può influenzare la funzione proteica ed è implicata in vari processi biologici, inclusi l'invecchiamento e la segnalazione cellulare. Il composto è solubile in acqua e solventi organici polari, rendendolo adatto per varie applicazioni biochimiche. Metionina solfossido può anche essere ridotto di nuovo a metionina da enzimi specifici, evidenziando il suo ruolo nella biologia redox. Il suo numero CAS, 3226-65-1, è utilizzato per l'identificazione in database chimici e contesti normativi. In generale, Metionina solfossido funge da importante biomarcatore per il danno ossidativo ed è di interesse negli studi relativi allo stress ossidativo e alla chimica delle proteine.

Formula: C₅H₁₁NO₃S

InChI: InChI=1S/C5H11NO3S/c1-10(9)3-2-4(6)5(7)8/h4H,2-3,6H2,1H3,(H,7,8)/t4-,10?/m0/s1

InChI key: InChIKey=QEFRNWWLZKMPFJ-YGVKFDHGSA-N

SMILES: [C@H](CCS(C)=O)(C(O)=O)N

Sinonimi:

• (2S)-2-amino-4-(methylsulfinyl)butanoic acid
• 2-Amino-4-(Methylsulfinyl)Butanoic Acid
• 3: PN: WO2011158590 PAGE: 34 claimed protein
• <span class="text-smallcaps">L</span>-Methionine sulfoxide
• <span class="text-smallcaps">L</span>-Methionine, S-oxide
• Butanoic acid, 2-amino-4-(methylsulfinyl)-, (2S)-
• Butyric acid, 2-amino-4-(methylsulfinyl)-, <span class="text-smallcaps">L</span>-
• H-Met(O)-OH
• Methionine sulfoxide
• methionine S-oxide
• L-Methionine, S-oxide
• Butyric acid, 2-amino-4-(methylsulfinyl)-, L-

L-Methionine sulfoxide

CAS: 3226-65-1

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Formula: C₅H₁₁NO₃S

Colore e forma: Powder, White to pale cream

Peso molecolare: 165.21

Ref: 02-J62873

H-Met(O)-OH

CAS: 3226-65-1

Formula: C₅H₁₁NO₃S

Purezza: > 99%

Colore e forma: White Powder

Peso molecolare: 165.21

Ref: 01-4014135

Butanoic acid, 2-amino-4-(methylsulfinyl)-, (2S)-

CAS: 3226-65-1

Formula: C₅H₁₁NO₃S

Purezza: 98%

Colore e forma: Solid

Peso molecolare: 165.2107

Ref: IN-DA00I649

L-Methionine sulfoxide

CAS: 3226-65-1

Formula: C₅H₁₁NO₃S

Purezza: (HPLC) ≥ 98.0%

Colore e forma: White to light yellow crystalline powder

Peso molecolare: 165.21

Ref: 7W-GM1929

Methionine EP Impurity A (L-Methionine Sulfoxide)

CAS: 3226-65-1

Formula: C₅H₁₁NO₃S

Colore e forma: White To Off-White Solid

Peso molecolare: 165.21

Ref: 4Z-M-477

H-Met(O)-Oh

CAS: 3226-65-1

H-Met(O)-Oh

Purezza: 98%

Peso molecolare: 165.21g/mol

Ref: 54-OR1013521

(2S)-2-Amino-4-[(RS)-methylsulfinyl]butanoic Acid (L-Methionine Sulfoxide)

Prodotto controllato

CAS: 3226-65-1

Formula: C₅H₁₁NO₃S

Colore e forma: White To Beige

Peso molecolare: 165.21

Ref: 86-MM0358.05

L-Methionine Sulfoxide

CAS: 3226-65-1

Formula: C₅H₁₁NO₃S

Purezza: >98.0%(HPLC)

Colore e forma: White to Light yellow powder to crystal

Peso molecolare: 165.21

Ref: 3B-M2097

L-Methionine sulfoxide

CAS: 3226-65-1

L-Methionine sulfoxide (H-Met(O)-OH) is a methionine metabolite affecting oxidative stress, purinergic signaling, and M1 macrophage polarization.

Formula: C₅H₁₁NO₃S

Purezza: 99.47% - 99.60%

Colore e forma: Solid

Peso molecolare: 165.21

Ref: TM-T19397

Methionine EP Impurity A

CAS: 3226-65-1

Formula: C₅H₁₁NO₃S

Peso molecolare: 165.21

Ref: ST-EA-CP-M105001

L-Methionine Sulfoxide

CAS: 3226-65-1

Stability Temperature Sensitive, Hygroscopic
Applications An intermediate in the synthesis of the acyclic amino carboxylic acid L-Methionine sulfoximine.
References Lee, B., et al.: J. Biol. Chem., 283, 28361 (2008), Nordqvist, A., et al.: Bioorg. Med. Chem., 16, 5501 (2008), Balog, E., et al.: Biochem., 48, 3005 (2009),

Formula: C₅H₁₁NO₃S

Colore e forma: White To Beige

Peso molecolare: 165.21

Ref: TR-M260450

L-Methionine Sulfoxide,13C

Prodotto controllato

CAS: 3226-65-1

Applications L-Methionine Sulfoxide 13C1 is a labelled analogue of L-Methionine Sulfoxide ( M260450). L-Methionine Sulfoxide ( M260450) an intermediate in the synthesis of the acyclic amino carboxylic acid L-Methionine sulfoximine.
References Lee, B., et al.: J. Biol. Chem., 283, 28361 (2008), Nordqvist, A., et al.: Bioorg. Med. Chem., 16, 5501 (2008);Balog, E., et al.: Biochem., 48, 3005 (2009);

Formula: CC₄H₁₁NO₃S

Colore e forma: White To Off-White

Peso molecolare: 166.203

Ref: TR-M260448

(2S)-2-Amino-4-(methylsulfinyl)butanoic acid

CAS: 3226-65-1

Formula: C₅H₁₁NO₃S

Purezza: 95%

Colore e forma: Solid

Peso molecolare: 165.21

Ref: 10-F323962

L-Methionine Sulphoxide extrapure, 99%

CAS: 3226-65-1

Formula: C₅H₁₁NO₃S

Purezza: min. 99%

Colore e forma: White, Powder

Peso molecolare: 165.21

Ref: SR-19485

L-Methionine sulfoxide

CAS: 3226-65-1

Methionine sulfoxide is a methionine that has been oxidized to methionine sulfoxide. Methionine sulfoxides are produced through protein oxidation, which is the chemical process of reacting with oxygen in the air or other compounds to form an organic peroxide and superoxide radical. Methionine sulfoxides are found in proteins and are formed as a result of oxidative stress on cells and tissues. The rate constant for the conversion of methionine to methionine sulfoxide is 0.01983 min-1 at pH 7, 25°C. There are two methods of detection: chemiluminescence method and chromatographic analysis. In addition, methionine sulfoxides have natural antioxidant properties that can be used to treat diseases such as Alzheimer's disease and Parkinson's disease, as well as cancer treatments. Methionine sulfoxides have been shown to have a significant effect on wild-type strains of bacteria, reducing their growth rates

Formula: C₅H₁₁NO₃S

Purezza: Min. 98 Area-%

Colore e forma: White Powder

Peso molecolare: 165.21 g/mol

Ref: 3D-FM25159