CAS 32634-68-7

Acido (+)-di-p-toluoil-D-tartarico

Descrizione:

Acido (+)-di-p-toluoil-D-tartarico, con il numero CAS 32634-68-7, è un composto organico chirale utilizzato principalmente nella sintesi asimmetrica e come agente di risoluzione per miscele racemiche. Questo composto è un derivato dell'acido tartarico, caratterizzato da due gruppi p-toluile legati ai gruppi idrossil della struttura dell'acido tartarico. È caratterizzato dalla sua capacità di formare sali diastereomerici stabili con varie ammine, il che facilita la separazione degli enantiomeri. Il composto è tipicamente un solido cristallino bianco a bianco sporco, che mostra una buona solubilità in solventi organici come etanolo e acetone, mentre è meno solubile in acqua. La sua chiralità e le caratteristiche strutturali contribuiscono alla sua utilità nell'industria farmaceutica, in particolare nello sviluppo di farmaci chirali. Inoltre, Acido (+)-di-p-toluoil-D-tartarico è noto per il suo punto di fusione relativamente alto e la rotazione ottica specifica, che sono indicativi della sua purezza e dell'eccesso enantiomerico. In generale, questo composto gioca un ruolo significativo nella stereochimica e nella sintesi di composti otticamente attivi.

Formula: C₂₀H₁₈O₈

InChI: InChI=1/C18H18O6/c1-11-3-7-13(8-4-11)23-15(17(19)20)16(18(21)22)24-14-9-5-12(2)6-10-14/h3-10,15-16H,1-2H3,(H,19,20)(H,21,22)

InChI key: InChIKey=CMIBUZBMZCBCAT-HOTGVXAUSA-N

SMILES: [C@@H]([C@H](OC(=O)C1=CC=C(C)C=C1)C(O)=O)(OC(=O)C2=CC=C(C)C=C2)C(O)=O

Sinonimi:

• (+)-Bis-O,O′-(4-toluoyl)-<span class="text-smallcaps">D</span>-tartrate
• (+)-Di-O,O′-p-toluoyltartaric acid
• (+)-Di-O,O′-p-toluyltartaric acid
• (+)-Di-O-(p-toluoyl)tartaric acid
• (+)-Di-O-p-toluoyl-<span class="text-smallcaps">D</span>-tartaric acid
• (+)-Di-p-toluoyl-<span class="text-smallcaps">D</span>-tartaric acid
• (+)-Di-p-toluoyl-D-tartaric acid
• (+)-Di-p-toluoyl-D-tartaric acid(Anhydrous)
• (+)-Di-p-toluoyltartaric acid
• (+)-Ditoluoyltartaric acid
• (+)-O,O-Di-p-toluoyltartaric acid
• (+)-O,O′-Di-p-toluoyl-<span class="text-smallcaps">D</span>-tartaric acid
• (-)-di-p-Toluyl-L-tartaric acid
• (2S,35)-(-)-di-o-4-Toluoyl-D-tartaric acid
• (2S,3S)-(+)-Di-p-toluoyltartaric acid
• (2S,3S)-2,3-Bis[(4-methylbenzoyl)oxy]succinic acid
• (2S,3S)-2,3-bis[(4-methylbenzoyl)oxy]butanedioic acid
• (S,S)-O,O′-Di-p-toluoyltartaric acid
• 2,3-Bis(4-Methylphenoxy)Butanedioic Acid
• 2,3-Bis[(4-Methylbenzoyl)Oxy]-,[S-(Theta,Theta)]-Butanedioicaci
• 2,3-Bis[(4-methylbenzoyl)oxy]succinic acid
• 2,3-Bis{[(4-Methylphenyl)Carbonyl]Oxy}Butanedioic Acid Hydrate
• 2,3-Di-O-Para-Toluoyl-D-Tartaricacidhydrate
• 2,3-Di-O-para-toluoyl-D-tartaric acid
• <span class="text-smallcaps">D</span>-Bis(O-4-methylbenzoyl)tartaric acid
• <span class="text-smallcaps">D</span>-Di-O,O′-p-toluyltartaric acid
• <span class="text-smallcaps">D</span>-Di-p-toluoyltartaric acid
• Butanedioic acid, 2,3-bis((4-methylbenzoyl)oxy)-, (2S,3S)-
• Butanedioic acid, 2,3-bis[(4-methylbenzoyl)oxy]-, [S-(R*,R*)]-
• D-Dtta
• Di-p-toluoyl-l-tartaric acid
• L-di-p-Toluyltartaric acid
• NSC 97592
• Tartaric acid, di-p-toluate, (+)-
• p-Toluic acid, diester with <span class="text-smallcaps">D</span>-tartaric acid
• p-Toluic acid, diester with D-tartaric acid
• D-PTTA
• O,O'-DI-P-TOLUOYL-D-TARTARIC ACID
• (+)-DI-P-TOLUOYL-D-TRATARIC ACID
• D-(+)-DI-P-TOLUOYL TARTARIC ACID
• D-(+)-TARTARIC ACID DI-4-TOLUOYL ESTER
• (+)-DTTA
• O,O'-DI-TOLUOYL-D-(+)-TARTARIC ACID
• D-(+)-TARTARIC ACID-O,O'-DI-P-TOLUOYL ESTER
• (+)-O,O'-DI-P-TOLUOYL-D-TARTARIC ACID
• (+)-DI-O,O'-P-TOLUYL-D-TARTARIC ACID
• DI-O-4-TOLUOYL-D-TARTARIC ACID
• (+)-DI-1,4-TOLUOYL-D-TARTARIC ACID
• (2S,3S)-2,3-BIS-(4-METHYL-BENZOYLOXY)-SUCCINIC ACID
• DI-(4-METHYL)BENZOYL-D-TARTARIC ACID
• L-(-)-DI-P-TOLUOYL-D-TARTARIC ACID

(+)-Di-p-toluoyl-D-tartaric Acid

CAS: 32634-68-7

Formula: C₂₀H₁₈O₈

Purezza: >98.0%(T)(HPLC)

Colore e forma: White to Almost white powder to crystal

Peso molecolare: 386.36

Ref: 3B-D1417

(+)-Di-p-toluoyl-D-tartaric acid

CAS: 32634-68-7

Formula: C₂₀H₁₈O₈

Purezza: 98%

Colore e forma: Solid, Crystalline Powder

Peso molecolare: 386.356

Ref: 10-F011666

Di-p-toluoyl-D-tartaric acid, 98%

CAS: 32634-68-7

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Sci

Formula: C₂₀H₁₈O₈

Purezza: 98%

Colore e forma: Crystals or powder or crystalline powder, White to off-white

Peso molecolare: 386.36

Ref: 02-L13223

Rivastigmine Related Compound A ((+)-Di-(p-toluoyl)-D-tartaric acid)

CAS: 32634-68-7

Salts and esters of tartaric acid

Formula: C₂₀H₁₈O₈

Colore e forma: Powder

Peso molecolare: 386.10017

Ref: 45-1604869

Di-p-toluoyl-D-tartaric Acid

CAS: 32634-68-7

Formula: C₂₀H₁₈O₈

Purezza: 98%

Colore e forma: Solid

Peso molecolare: 386.3521

Ref: IN-DA0032AX

Rivastigmine USP Related Compound A

CAS: 32634-68-7

Formula: C₂₀H₁₈O₈

Colore e forma: White To Off-White Solid

Peso molecolare: 386.36

Ref: 4Z-R-0720

(2S,3S)-(+)-2,3-Bis[(4-methylbenzoyl)oxy]butane-1,4-dioic acid

CAS: 32634-68-7

(2S,3S)-(+)-2,3-Bis[(4-methylbenzoyl)oxy]butane-1,4-dioic acid

Formula: C₂₀H₁₈O₈

Purezza: 99%

Colore e forma: white crystalline powder

Peso molecolare: 386.35g/mol

Ref: 54-OR14900

Di-p-toluoyl-D-tartaric acid

CAS: 32634-68-7

Formula: C₂₀H₁₈O₈

Purezza: ≥ 98.0%

Colore e forma: White to off-white crystalline powder

Peso molecolare: 386.36

Ref: 7W-GK4062

(+)-Di-p-toluoyl-D-(+)-tartaric Acid

CAS: 32634-68-7

Colore e forma: Neat

Ref: 86-MM1497.03

(+)-O,O'-Di-p-toluoyl-D-tartaric acid

CAS: 32634-68-7

(+)-O,O'-Di-p-toluoyl-D-tartaric acid is a potent and selective ligand for the dopamine D2 receptor. It was first synthesized in 1968 and has been extensively studied for its interactions with dopamine receptors. (+)-O,O'-Di-p-toluoyl-D-tartaric acid has been shown to be an orthosteric agonist at the D2 receptor, meaning it binds directly to the receptor in the absence of any other compounds. It binds to the extracellular site of the receptor, with a binding affinity that is 10 times more potent than that of apomorphine. The compound has been shown to have antidepressant effects when administered systemically, as well as in animal models of depression. This activity may be due to its ability to selectively activate dopamine D2 receptors in regions such as the prefrontal cortex.

Formula: C₂₀H₁₈O₈

Purezza: Min. 95%

Colore e forma: Powder

Peso molecolare: 386.35 g/mol

Ref: 3D-FD22531

(+)-O,O’-Di-p-toluoyl-D-tartaric Acid

CAS: 32634-68-7

Impurity Rivastigmine USP Related Compound A
Applications Inhibitor of enzyme. Rivastigmine USP Related Compound A.
References Olsen,L., et al.: Bioorg. Med. Chem., 14, 2627 (2007),

Formula: C₂₀H₁₈O₈

Colore e forma: Neat

Peso molecolare: 386.35

Ref: TR-D494380

Rivastigmine USP Related Compound A

CAS: 32634-68-7

Formula: C₂₀H₁₈O₈

Peso molecolare: 386.37

Ref: ST-EA-CP-R27038