CAS 32677-01-3

Acido L-glutammico, 1,5-bis(1,1-dimetiletil) estere, cloridrato (1:1)

Descrizione:

Acido L-glutammico, 1,5-bis(1,1-dimetiletil) estere, cloridrato (1:1), con numero CAS 32677-01-3, è un derivato dell'aminoacido L-acido glutammico. Questo composto presenta una modifica dell'estere bis(1,1-dimetiletil), che ne migliora la lipofilia e la stabilità rispetto all'aminoacido genitore. Come sale cloridrato, è tipicamente più solubile in acqua, facilitando il suo utilizzo in varie applicazioni biochimiche. La presenza dei gruppi estere può influenzare la sua reattività e attività biologica, influenzando potenzialmente il suo ruolo nelle vie metaboliche o come neurotrasmettitore. Questo composto è spesso studiato per le sue potenziali applicazioni in farmacologia, in particolare nello sviluppo di farmaci che mirano ai recettori del glutammato o a vie correlate. Le sue caratteristiche strutturali, inclusi i voluminosi gruppi dimetiletil, possono anche influenzare la sua interazione con i sistemi biologici, rendendolo un argomento di interesse in chimica medicinale e progettazione di farmaci. In generale, l'acido L-glutammico, 1,5-bis(1,1-dimetiletil) estere, cloridrato è un aminoacido chimicamente modificato con proprietà uniche adatte per varie indagini scientifiche.

Formula: C₁₃H₂₅NO₄·ClH

InChI: InChI=1S/C13H25NO4.ClH/c1-12(2,3)17-10(15)8-7-9(14)11(16)18-13(4,5)6;/h9H,7-8,14H2,1-6H3;1H/t9-;/m0./s1

InChI key: InChIKey=LFEYMWCCUAOUKZ-FVGYRXGTSA-N

SMILES: C([C@H](CCC(OC(C)(C)C)=O)N)(OC(C)(C)C)=O.Cl

Sinonimi:

• <span class="text-smallcaps">L</span>-Glutamic acid di-tert-butyl ester hydrochloride
• <span class="text-smallcaps">L</span>-Glutamic acid, 1,5-bis(1,1-dimethylethyl) ester, hydrochloride (1:1)
• <span class="text-smallcaps">L</span>-Glutamic acid, bis(1,1-dimethylethyl) ester, hydrochloride
• Di-tert-butyl (S)-2-aminopentanedioate hydrochloride
• Di-tert-butyl <span class="text-smallcaps">L</span>-glutamate hydrochloride
• Di-tert-butyl glutamate hydrochloride
• Glu(OtBu)-OtBu HCl
• Glutamic acid di-tert-butyl ester hydrochloride
• Glutamic acid, di-tert-butyl ester, hydrochloride, <span class="text-smallcaps">L</span>-
• H-Glu(OtBu)-OtBu.HCl
• H-Glu(OtBu)-OtBu・HCl
• L-(g-O-Bu)-Glu-O-tert-Bu HCl
• L-Glutamic Acid Di-Tert-Butyl Ester Hydrochloride
• L-Glutamic Acid Di-tert-Butyl Ester HCl Salt
• NSC 94681
• di-tert-butyl L-glutamate hydrochloride (1:1)
• L-Glutamic acid, bis(1,1-dimethylethyl) ester, hydrochloride
• Glutamic acid, di-tert-butyl ester, hydrochloride, L-

H-Glu(OtBu)-OtBu·HCl

CAS: 32677-01-3

Formula: C₁₃H₂₅NO₄·HCl

Purezza: >98.0%(T)

Colore e forma: White to Light yellow powder to crystal

Peso molecolare: 295.80

Ref: 3B-D6026

L-Glutamic acid di-tert-butyl ester hydrochloride, 98%

CAS: 32677-01-3

L-Glutamic acid di-tert-butyl ester may be useful in the synthesis of substance P antagonistic peptides. This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa A

Formula: C₁₃H₂₆ClNO₄

Purezza: 98%

Colore e forma: White to pale cream or pale yellow, Powder or crystals or crystalline powder

Peso molecolare: 295.80

Ref: 02-H63708

H-Glu(OtBu)-OtBu · HCl

CAS: 32677-01-3

Bachem ID: 4000156.

Formula: C₁₃H₂₅NO₄·HCl

Purezza: > 99%

Colore e forma: White Powder

Peso molecolare: 295.81

Ref: 01-4000156

L-Glutamic acid di-tert-butyl ester hydrochloride

CAS: 32677-01-3

Formula: C₁₃H₂₆ClNO₄

Purezza: 96%

Colore e forma: Solid

Peso molecolare: 295.8028

Ref: IN-DA0037EF

L-Glutamic acid di-tert-butyl ester hydrochloride

CAS: 32677-01-3

Formula: C₁₃H₂₅NO₄·HCl

Purezza: ≥ 98.0%

Colore e forma: White powder

Peso molecolare: 295.80

Ref: 7W-GM3288

Di-tert-butyl L-glutamate hydrochloride

CAS: 32677-01-3

Di-tert-butyl L-glutamate hydrochloride

Formula: C₁₃H₂₅NO₄·ClH

Purezza: 98%

Colore e forma: white solid

Peso molecolare: 295.80g/mol

Ref: 54-OR52525

L-Glutamic acid di-tert-butyl ester hydrochloride

CAS: 32677-01-3

L-glutamic acid di-tert-butyl ester hydrochloride is a synthetic glutamic acid conjugate that can be used in the treatment of cancer. L-Glutamic acid di-tert-butyl ester hydrochloride is a substrate for many enzymes, such as glutamate transporters and glutaminase, which are found in tumor cells. It has been shown to decrease the uptake of docetaxel by tumor xenografts in mice. The expression of L-Glutamic acid di-tert-butyl ester hydrochloride has been observed in tissues during cancerous growth and it is expressed at higher levels than in normal tissues.

Formula: C₁₃H₂₅NO₄·HCl

Purezza: Min. 95%

Colore e forma: White Powder

Peso molecolare: 295.8 g/mol

Ref: 3D-FG33471

H-Glu(OtBu)-OtBu.HCl

CAS: 32677-01-3

M02970 - H-Glu(OtBu)-OtBu.HCl

Formula: C₁₃H₂₆ClNO₄

Purezza: 96%

Colore e forma: Solid

Peso molecolare: 295.8

Ref: 10-M02970

Di-tert-butyl Glutamate Hydrochloride

Prodotto controllato

CAS: 32677-01-3

Applications Di-tert-butyl Glutamate Hydrochloride is a reagent in the synthesis of Fructose-glutamic Acid (F795660); an amadori compound (derivatives of aminodeoxysugars) that is formed in food (such as dehydrated fruits such as tomatoes and carrots) as a result of the Maillard reactions.
References Baltes, W.: Food Chem., 9, 59 (1982); Sanz, M., et al.: J. Agr. Food Chem., 49, 5228 (2001); Wellner, A., et al.: J. Agr. Food Chem., 59, 7992 (2011)

Formula: C₁₃H₂₆ClNO₄

Colore e forma: Neat

Peso molecolare: 295.8

Ref: TR-D493735