CAS 328-50-7

Acido 2-ossoglutarico

Descrizione:

Acido 2-ossoglutarico, noto anche come alfa-cetoglutarato, è un intermedio chiave nel ciclo di Krebs, essenziale per la respirazione cellulare e la produzione di energia negli organismi aerobici. È un acido dicarbossilico con la formula molecolare C5H6O5 e presenta due gruppi carbossilici (-COOH) e un gruppo chetonico (C=O). Questo composto si trova tipicamente nella sua forma anionica, nota come alfa-cetoglutarato, a pH fisiologico. Svolge un ruolo cruciale nel metabolismo degli aminoacidi e nella sintesi dei neurotrasmettitori. Inoltre, Acido 2-ossoglutarico è coinvolto nella regolazione dei processi cellulari, inclusa la modulazione dell'espressione genica e il mantenimento dell'equilibrio redox cellulare. Viene anche studiato per le sue potenziali applicazioni terapeutiche, incluso il suo ruolo come integratore alimentare per migliorare le prestazioni atletiche e il suo coinvolgimento in vari disturbi metabolici. Il composto è generalmente riconosciuto come sicuro se usato correttamente, ma i suoi effetti possono variare in base al dosaggio e alle condizioni di salute individuali.

Formula: C₅H₆O₅

InChI: InChI=1S/C5H6O5/c6-3(5(9)10)1-2-4(7)8/h1-2H2,(H,7,8)(H,9,10)

InChI key: InChIKey=KPGXRSRHYNQIFN-UHFFFAOYSA-N

SMILES: C(CCC(O)=O)(C(O)=O)=O

Sinonimi:

• 2-Ketoglutaric acid
• 2-Oxo-1,5-pentanedioic acid
• 2-Oxoglutaric Acid
• 2-Oxoglutarsaure
• 2-Oxopentanedioic acid
• Acide 2-oxoglutarique
• Acido 2-Oxoglutarico
• Glutaric acid, 2-oxo-
• Nsc 17391
• α-Ketoglutaric acid
• α-Oxoglutaric acid
• α-Oxopentanedioic acid
• α-keto-Glutaric acid
• 2-oxo-pentanedioicaci
• alpha-Ketoglutaric Acid
• 2-Oxpentanedioicacid
• 2-oxopentanedioate
• 2-KETOGLUTARIC ACID, DISODIUM SALT, DIHYDRATE BIOTECh GRADE 99.5%
• diammonium 2-oxopentanedioate
• 2-KETOGLUTARIC ACID 99+%
• Oxoglutaric acid
• KETO-GLU
• GAMMA-KETOGLUTARIC ACID
• -Ketoglutaricacid
• α-Ketoglutaricacid
• A-KETOGLUTARIC ACID FREE ACID CELL*CULTU RE TESTED
• 2-OXOPENTANDIOICACID
• Glutaric acid, alpha keto
• KetoglutaricAcid,FreeAcid
• N-oxoglutamic acid
• 2-KETOGLUTARIC ACID BIOSYNTH
• alpha-keto-Glutaric acid
• Pentanedioic acid, 2-oxo-
• A-KetoglutaricAcidPuriss
• FEMA 3891
• 2-Oxo-1,5-dipentanedioic acid
• PENTANEDIOIC ACID, 2-OXO-

2-Oxoglutaric Acid

CAS: 328-50-7

Formula: C₅H₆O₅

Purezza: >99.0%(T)

Colore e forma: White to Light yellow powder to crystal

Peso molecolare: 146.10

Ref: 3B-K0005

2-Ketoglutaric acid, 98%

CAS: 328-50-7

2-Ketoglutaric acid is used as an intermediate in the kreb’s cycle catalyzed by glutamate dehydrogenase enzyme on glutamate. It is also used in dietary supplements to improve protein synthesis. This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. So

Formula: C₅H₆O₅

Purezza: 98%

Colore e forma: White to pale yellow, Crystals or powder or crystalline powder

Peso molecolare: 146.10

Ref: 02-A10256

2-Ketoglutaric Acid

CAS: 328-50-7

Formula: C₅H₆O₅

Purezza: 95%

Colore e forma: Solid

Peso molecolare: 146.0981

Ref: IN-DA003HHY

2-Ketoglutaric acid

CAS: 328-50-7

Formula: C₅H₆O₅

Purezza: (Titration) 98.0 - 101.5 %

Colore e forma: White to off-white crystalline powder

Peso molecolare: 146.10

Ref: 7W-GP9006

2-Ketoglutaric acid

CAS: 328-50-7

2-Ketoglutaric acid

Purezza: ≥98%

Peso molecolare: 146.1g/mol

Ref: 54-BUP19492

2-Oxopentanedioic acid

CAS: 328-50-7

2-Oxopentanedioic acid

Formula: C₅H₆O₅

Purezza: 95

Colore e forma: white to off white solid

Peso molecolare: 146.10g/mol

Ref: 54-OR4662

2-Oxo-1,5-pentanedioic Acid-d6

CAS: 1173021-86-7, 328-50-7

Purezza: 98 atom % D

Peso molecolare: 152.14

Ref: 3U-D8105

2-Ketoglutaric acid

CAS: 328-50-7

2-Ketoglutaric acid is a reversible inhibitor of tyrosinase (IC50=15 mM). 2-Ketoglutaric acid is an intermediate of the Krebs cycle. High-Quality, Low-Cost!

Formula: C₅H₆O₅

Purezza: 99.28%

Colore e forma: Solid

Peso molecolare: 146.1

Ref: TM-T5980

2-Oxopentanedioic acid

CAS: 328-50-7

Formula: C₅H₆O₅

Purezza: 95%

Colore e forma: Powder or Crystalline Powder

Peso molecolare: 146.098

Ref: 10-F069250

2-Ketoglutaric Acid

CAS: 328-50-7

Applications 2-Ketoglutaric Acid is a derivative of glutaric acid and is an intermediate in the kreb’s cycle catalyzed by glutamate dehydrogenase enzyme on glutamate.
References Son, J.Y., et al.: Nature., 496, 7443 (2013); Quartarao, C.E., et al.: Biochem., 52, 1765 (2013); Yum, S.H., et al.: Euro.J. Pharmacol., 699, 124 (2013);

Formula: C₅H₆O₅

Colore e forma: Off White Powder

Peso molecolare: 146.10

Ref: TR-K191200

2-Ketoglutaric acid

CAS: 328-50-7

Used to differentiate microorganisms based on their metabolic properties.

Formula: C₅H₆O₅

Peso molecolare: 146.10 g/mol

Ref: 3D-K-2400

a-Ketoglutaric acid

CAS: 328-50-7

a-Ketoglutaric acid is a naturally occurring organic compound that is found in the body as well as in plants. It belongs to the group of organic acids and is produced from the breakdown of amino acids, such as leucine and valine. a-Ketoglutaric acid has been shown to have physiological effects on cells and tissues by inhibiting enzymes involved in energy metabolism. In vitro assays have shown that a-ketoglutaric acid has inhibitory properties against plant metabolism. This drug also inhibits the transcriptional regulation of genes for fatty acid synthesis in human erythrocytes.
A-ketoglutaric acid has also been shown to inhibit glucose production in rat liver cells, which may be due to its ability to bind covalently with proteins or lipids, changing their structures and functions.

Formula: C₅H₆O₅

Colore e forma: White Off-White Powder

Peso molecolare: 146.1 g/mol

Ref: 3D-FK09820

a-Ketoglutaric Acid (High Purity) extrapure AR, 99.5%

CAS: 328-50-7

Formula: C₅H₆O₅

Purezza: min. 99.5%

Colore e forma: White to pale yellow, Crystalline powder, Clear, Colourless to pale yellow

Peso molecolare: 146.10

Ref: SR-28386

a-Ketoglutaric Acid extrapure, 99%

CAS: 328-50-7

Formula: C₅H₆O₅

Purezza: min. 99%

Colore e forma: White to pale yellow, Crystalline powder, Clear, Colourless to pale yellow

Peso molecolare: 146.10

Ref: SR-93929