CAS 32981-85-4

(2R,3S)-N-benzoil-3-fenilisoserina estere metilico

Descrizione:

(2R,3S)-N-benzoil-3-fenilisoserina estere metilico è un composto chimico caratterizzato dalla sua stereochimica specifica e dai gruppi funzionali. Presenta un gruppo benzilico, che è un gruppo carbonile attaccato a un anello fenilico, indicando il suo potenziale per interazioni tipiche dei composti aromatici. La presenza della parte isoserina suggerisce che ha sia gruppi funzionali amminici che idrossilici, contribuendo alla sua potenziale solubilità in solventi polari. La funzionalità dell'estere metilico indica che il gruppo acido carbossilico dell'isoserina è esterificato, il che può aumentare la lipofilia e influenzare la sua reattività. Questo composto può mostrare attività biologica a causa della sua somiglianza strutturale con gli amminoacidi, rendendolo di interesse nella chimica farmaceutica. La sua stereochimica, denotata dalla configurazione (2R,3S), è cruciale per le sue interazioni biologiche, poiché la disposizione spaziale degli atomi può influenzare significativamente le proprietà e il comportamento del composto nei sistemi biologici. In generale, la struttura unica di questo composto lo posiziona come una molecola potenzialmente preziosa nella chimica medicinale e nei campi correlati.

Formula: C₁₇H₁₇NO₄

InChI: InChI=1S/C17H17NO4/c1-22-17(21)15(19)14(12-8-4-2-5-9-12)18-16(20)13-10-6-3-7-11-13/h2-11,14-15,19H,1H3,(H,18,20)/t14-,15+/m0/s1

InChI key: InChIKey=UYJLJICUXJPKTB-LSDHHAIUSA-N

SMILES: [C@@H](NC(=O)C1=CC=CC=C1)([C@H](C(OC)=O)O)C2=CC=CC=C2

Sinonimi:

• (2R,3S)-1-benzoyl-2-hydroxy-3-aminophenylpionic acid ester
• (2R,3S)-Methyl 3-benzoylamino-2-hydroxy-3-phenylpropanoate
• (2R,3S)-N-Benzoyl-3-phenylisoserine methyl ester
• Benzenepropanoic acid, β-(benzoylamino)-α-hydroxy-, methyl ester, (αR,βS)-
• Benzenepropanoic acid, β-(benzoylamino)-α-hydroxy-, methyl ester, [R-(R*,S*)]-
• Isoserine, N-benzoyl-3-phenyl-, methyl ester, (2R,3S)-
• Lkt-T 0104
• Methyl (-)-(2R,3S)-3-benzoylamino-2-hydroxy-3-phenylpropionate
• Methyl(2R,3S)-3-(benzoylamino)-2-hydroxy-3-phenylpropanoale
• Methyl(2R,3S)-N-benzoylphenylisoserinate
• Methyl-(2R,3S)-N-Benzoyl-3-Phenylisos
• N-Benzoyl-3-Phenyl isoserine methyl ester
• Paclitaxel Side Chain No.4
• methyl (2R,3S)-3-(benzoylamino)-2-hydroxy-3-phenylpropanoate
• methyl (2R,3S)-3-benzamido-2-hydro-3-phenylpropionate

Methyl (2R,3S)-3-benzamido-2-hydroxy-3-phenylpropionate, 98%

CAS: 32981-85-4

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Sci

Formula: C₁₇H₁₇NO₄

Purezza: 98%

Peso molecolare: 299.33

Ref: 02-H61641

Benzenepropanoic acid, b-(benzoylamino)-a-hydroxy-, methyl ester,(aR,bS)-

CAS: 32981-85-4

Formula: C₁₇H₁₇NO₄

Purezza: 98%

Colore e forma: Solid

Peso molecolare: 299.3212

Ref: IN-DA00I6BS

Bz-RS-ISer(3-Ph)-Ome

CAS: 32981-85-4

Bz-RS-ISer(3-Ph)-Ome

Purezza: ≥98%

Peso molecolare: 299.32g/mol

Ref: 54-BUP17991

(2R,3S)-N-Benzoyl-3-phenylisoserine methyl ester

CAS: 32981-85-4

(2R,3S)-N-Benzoyl-3-phenylisoserine methyl ester

Purezza: 98%

Peso molecolare: 299.32g/mol

Ref: 54-OR315016

Methyl (2R,3S)-3-(benzoylamino)-2-hydroxy-3-phenylpropanoate

CAS: 32981-85-4

Formula: C₁₇H₁₇NO₄

Peso molecolare: 299.33

Ref: 7W-GY0500

Methyl (2R,3S)-3-Benzamido-2-hydroxy-3-phenylpropanoate

Prodotto controllato

CAS: 32981-85-4

Formula: C₁₇H₁₇NO₄

Colore e forma: Neat

Peso molecolare: 299.32

Ref: 86-MM1489.09

Methyl (2R,3S)-3-(benzoylamino)-2-hydroxy-3-phenylpropanoate

CAS: 32981-85-4

Formula: C₁₇H₁₇NO₄

Purezza: 95%~99%

Peso molecolare: 299.326

Ref: BP-BP4346

Bz-RS-ISer(3-Ph)-Ome

CAS: 32981-85-4

Bz-RS-ISer(3-Ph)-Ome (Methyl (2R,3S)-3-(benzoylamino)-2-hydroxy-3-phenylpropanoate) is a paclitaxel derivative that inhibits the HSV replication cycle.

Formula: C₁₇H₁₇NO₄

Purezza: 99.36% - 99.89%

Colore e forma: White Crystal

Peso molecolare: 299.32

Ref: TM-T7055

Paclitaxel Impurity 11

CAS: 32981-85-4

Formula: C₁₇H₁₇NO₄

Peso molecolare: 299.33

Ref: 4Z-P-2850

(2R,3S)-N-Benzoyl-3-phenyl Isoserine Methyl Ester

Prodotto controllato

CAS: 32981-85-4

Applications (2R,3S)-N-Benzoyl-3-phenyl Isoserine Methyl Ester is an intermediate in the preparation of potent anticancer drug Paclitaxel (P132500) used to study the location of the binding sites.
References Paal, K. et al.: Bioorg. Med. Chem., 15, 1323 (2007); Krawczyk, E. et al.: J. Pharm. Pharmacol., 57, 791 (2005);

Formula: C₁₇H₁₇NO₄

Colore e forma: Off White Powder

Peso molecolare: 299.32

Ref: TR-B208560

Methyl (2R,3S)-N-benzoyl-3-phenylisoserine

CAS: 32981-85-4

Methyl (2R,3S)-N-benzoyl-3-phenylisoserine is a potent anticancer drug that inhibits the growth of tumor cells. It has been shown to be effective against breast cancer and prostate cancer cell lines and is currently being tested in clinical trials for its antitumor activity. Methyl (2R,3S)-N-benzoyl-3-phenylisoserine has been shown to induce apoptosis in a number of tumor cell lines and may function by increasing the intracellular level of reactive oxygen species. This drug also binds to microtubules, which are essential for the mitotic spindle assembly checkpoint that prevents cells from entering mitosis until all chromosomes are properly aligned at the metaphase plate.
Methyl (2R,3S)-N-benzoyl-3-phenylisoserine belongs to the group of taxane drugs and was first isolated from Taxus brevif

Formula: C₁₇H₁₇NO₄

Purezza: Min. 95%

Colore e forma: White/Off-White Solid

Peso molecolare: 299.32 g/mol

Ref: 3D-FM32203

(2R,3S)-Methyl 3-benzamido-2-hydroxy-3-phenylpropanoate

CAS: 32981-85-4

Formula: C₁₇H₁₇NO₄

Purezza: ≥98%

Peso molecolare: 299.326

Ref: 10-F213091

Paclitaxel Impurity 54

CAS: 32981-85-4

Formula: C₁₇H₁₇NO₄

Peso molecolare: 299.33

Ref: ST-EA-CP-P36033