CAS 33171-05-0

Bisdemetossicurcumina

Descrizione:

Bisdemetossicurcumina è un derivato sintetico della curcumina, che è il composto attivo presente nella curcuma. È caratterizzato dalla sua unica struttura chimica, che manca di due gruppi metossilici presenti nella curcumina, risultando in proprietà fisiche e chimiche distinte. Questo composto di solito presenta un colore giallo-arancio ed è noto per le sue potenziali attività biologiche, comprese le proprietà anti-infiammatorie, antiossidanti e anticancerogene. Bisdemetossicurcumina è solubile in solventi organici ma ha una solubilità limitata in acqua, il che può influenzare la sua biodisponibilità. Si pensa che il suo meccanismo d'azione coinvolga la modulazione di vari percorsi di segnalazione, rendendolo un argomento di interesse nella ricerca farmacologica. Inoltre, studi hanno indicato che potrebbe aumentare l'efficacia di alcuni agenti chemioterapici. Come molti composti derivati da fonti naturali, sono necessarie ulteriori ricerche per comprendere appieno il suo potenziale terapeutico e il profilo di sicurezza.

Formula: C₁₉H₁₆O₄

InChI: InChI=1S/C19H16O4/c20-16-7-1-14(2-8-16)5-11-18(22)13-19(23)12-6-15-3-9-17(21)10-4-15/h1-12,20-21H,13H2/b11-5+,12-6+

InChI key: InChIKey=PREBVFJICNPEKM-YDWXAUTNSA-N

SMILES: C(=C/C(CC(/C=C/C1=CC=C(O)C=C1)=O)=O)\C2=CC=C(O)C=C2

Sinonimi:

• (1E,6E)-1,7-Bis(4-hydroxyphenyl)-1,6-heptadiene-3,5-dione
• (1E,6E)-1,7-bis(4-hydroxyphenyl)hepta-1,6-diene-3,5-dione
• (1E,6E)-Bis(demethoxy)curcumin
• 1,6-Heptadiene-3,5-dione, 1,7-bis(4-hydroxyphenyl)-, (1E,6E)-
• 1,6-Heptadiene-3,5-dione, 1,7-bis(p-hydroxyphenyl)-, (E,E)-
• 1,7-Bis(4-Hydroxyphenyl)Hepta-1,6-Diene-3,5-Dione
• Bisdesmethoxycurcumin
• Curcumin III
• Didemethoxycurcumin
• Bisdemethoxycurcumin

Bisdemethoxycurcumin

CAS: 33171-05-0

Formula: C₁₉H₁₆O₄

Purezza: >95.0%(T)(HPLC)

Colore e forma: Light yellow to Yellow to Orange powder to crystal

Peso molecolare: 308.33

Ref: 3B-B6548

Bisdemethoxycurcumin

CAS: 33171-05-0

Bisdemethoxycurcumin analytical standard provided with w/w absolute assay, to be used for quantitative titration.

Formula: C₁₉H₁₆O₄

Purezza: (HPLC) ≥98%

Colore e forma: Powder

Peso molecolare: 308.33

Ref: 11-4745S

Bisdesmethoxycurcumin

CAS: 33171-05-0

Ketone-phenols and ketones with other oxygen function

Formula: C₁₉H₁₆O₄

Colore e forma: Yellow Orange Powder

Peso molecolare: 308.10486

Ref: 45-1075305

(1E,6E)-Bis(demethoxy)curcumin

CAS: 33171-05-0

(1E,6E)-Bis(demethoxy)curcumin

Purezza: ≥95%

Peso molecolare: 308.33g/mol

Ref: 54-BUP00209

Bisdemethoxycurcumin

CAS: 33171-05-0

Bisdemethoxycurcumin can regulate anti-inflammatory and anti-proliferative responses through a ROS-independent mechanism, also suppresses MCF-7 cells proliferation by inducing ROS accumulation and modulating senescence-related pathways.

Formula: C₁₉H₁₆O₄

Purezza: 95%~99%

Colore e forma: Yellow powder

Peso molecolare: 308.333

Ref: BP-BP0278

Bisdemethoxycurcumin

CAS: 33171-05-0

Colore e forma: Neat

Ref: 04-CA10651707

(1E,6E)-Bis(demethoxy)curcumin

CAS: 33171-05-0

(1E,6E)-Bis(demethoxy)curcumin (Curcumin III) is a natural demethoxy derivative of curcumin,with anti-inflammatory and anti-cancer activities.

Formula: C₁₉H₁₆O₄

Purezza: 97.45% - 98.39%

Colore e forma: Solid

Peso molecolare: 308.33

Ref: TM-T6S1688

Bisdemethoxycurcumin

CAS: 33171-05-0

Formula: C₁₉H₁₆O₄

Peso molecolare: 308.33

Ref: 7W-GY6887

Bisdemethoxy Curcumin

CAS: 33171-05-0

Formula: C₁₉H₁₆O₄

Peso molecolare: 308.33

Ref: 4Z-C-6923

Bisdemethoxycurcumin

CAS: 33171-05-0

Ketone phenol

Formula: C₁₉H₁₆O₄

Purezza: ≥ 95.0 % (HPLC)

Colore e forma: Powder

Peso molecolare: 308.33

Ref: 5G-89582

(E,E)-Bisdemethoxycurcumin

Prodotto controllato

CAS: 33171-05-0

Stability Light Sensitive
Applications Bisdemethoxycurcumin is one of the three major forms of curcuminoids found in the rhizomes of turmeric. Bisdemethoxycurcumin displays antioxidant, anti-inflammatory as well as chemotherapeutic activity. Bisdemethoxycurcumin acts as an inhibitor of human pancreatic α-amylase, a target for type-2 diabetes .
References Ponnusamy, S. et al.: Food Chem., 135, 2638 (2012); Hung, C.-M. et al.: J. Agric. Food. Chem., 60, 8427 (2012); Jayaprakasha, G.K. et al.: Food Chem., 98, 720 (2006);

Formula: C₁₉H₁₆O₄

Colore e forma: Orange To Dark Orange

Peso molecolare: 308.33

Ref: TR-B425800

(E,E)-Bisdemethoxycurcumin-d8

Prodotto controllato

CAS: 33171-05-0

Applications Labelled analogue of Bisdemethoxycurcumin, one of the three major forms of curcuminoids found in the rhizomes of turmeric. Bisdemethoxycurcumin displays antioxidant, anti-inflammatory as well as chemotherapeutic activity. Bisdemethoxycurcumin acts as an inhibitor of human pancreatic α-amylase, a target for type-2 diabetes .
References Ponnusamy, S. et al.: Food Chem., 135, 2638 (2012); Hung, C.-M. et al.: J. Agric. Food. Chem., 60, 8427 (2012); Jayaprakasha, G.K. et al.: Food Chem., 98, 720 (2006);

Formula: C₁₉H₈D₈O₄

Colore e forma: Neat

Peso molecolare: 316.38

Ref: TR-B425802

(E,E)-Bisdemethoxycurcumin

CAS: 33171-05-0

(E,E)-Bisdemethoxycurcumin is a natural curcuminoid, which is a type of polyphenolic compound. This compound is sourced primarily from the rhizomes of the turmeric plant, Curcuma longa. Its molecular structure is characterized by the absence of methoxy groups, distinguishing it from other curcuminoids.

Formula: C₁₉H₁₆O₄

Purezza: Min. 98 Area-%

Colore e forma: Powder

Peso molecolare: 308.33 g/mol

Ref: 3D-FB64958

(E,E)-Bisdemethoxycurcumin - Bio-X ™

CAS: 33171-05-0

Bisdemethoxycurcumin is a natural product that has been shown to inhibit the growth of cancer cells by inducing apoptosis. Bisdemethoxycurcumin also inhibits the production of inflammatory cytokines and chemokines in human monocytes, which may be beneficial for bowel disease. This compound has been shown to have antioxidant effects and anti-inflammatory properties.

Formula: C₁₉H₁₆O₄

Purezza: Min. 95%

Colore e forma: Powder

Peso molecolare: 308.33 g/mol

Ref: 3D-BB300038

(E,E)-Bisdemethoxycurcumin

CAS: 33171-05-0

Purezza: 96%

Colore e forma: Solid

Peso molecolare: 308.3330078

Ref: 10-F801840

Bisdemethoxycurcumin

CAS: 33171-05-0

Formula: C₁₉H₁₆O₄

Peso molecolare: 308.33

Ref: ST-EA-CP-C147001

Bisdemethoxycurcumin

CAS: 33171-05-0

Formula: C₁₉H₁₆O₄

Colore e forma: Solid

Peso molecolare: 308.3279

Ref: IN-DA003BFG