CAS 3338-32-7

Estere 4-terz-butil-1-(N-succinimidil) dell'acido Z-L-aspartico

Descrizione:

Estere 4-terz-butil-1-(N-succinimidil) dell'acido Z-L-aspartico, con il numero CAS 3338-32-7, è un composto chimico che funge da derivato dell'acido aspartico, un amminoacido importante in biochimica. Questo composto presenta un gruppo Z-protettivo, che ne migliora la stabilità e la solubilità, rendendolo adatto per varie applicazioni sintetiche, in particolare nella sintesi di peptidi. La presenza del moiety estere succinimidilico indica che può essere utilizzato per reazioni di accoppiamento, facilitando la formazione di legami ammidici con nucleofili, come le ammine. Il gruppo tert-butile contribuisce all'ostruzione sterica, che può influenzare la reattività e la selettività del composto nelle reazioni chimiche. Estere 4-terz-butil-1-(N-succinimidil) dell'acido Z-L-aspartico è spesso utilizzato nello sviluppo di farmaci e bioconjugati, grazie alla sua capacità di modificare selettivamente le biomolecole. La sua stabilità in condizioni fisiologiche e la compatibilità con vari gruppi funzionali lo rendono uno strumento prezioso nella sintesi organica e nella chimica medicinale.

Formula: C₂₀H₂₄N₂O₈

InChI: InChI=1/C20H24N2O8/c1-20(2,3)29-17(25)11-14(18(26)30-22-15(23)9-10-16(22)24)21-19(27)28-12-13-7-5-4-6-8-13/h4-8,14H,9-12H2,1-3H3,(H,21,27)

InChI key: InChIKey=JUMSBOKRGDETHL-AWEZNQCLSA-N

SMILES: O(C([C@@H](NC(OCC1=CC=CC=C1)=O)CC(OC(C)(C)C)=O)=O)N2C(=O)CCC2=O

Sinonimi:

• <span class="text-smallcaps">L</span>-Aspartic acid, N-[(phenylmethoxy)carbonyl]-, 4-(1,1-dimethylethyl) 1-(2,5-dioxo-1-pyrrolidinyl) ester
• Aspartic acid, N-carboxy-, N-benzyl 4-tert-butyl ester, succinimido deriv., <span class="text-smallcaps">L</span>-
• Butanoic acid, 4-[(2,5-dioxo-1-pyrrolidinyl)oxy]-4-oxo-3-[[(phenylmethoxy)carbonyl]amino]-, 1,1-dimethylethyl ester, (3S)-
• Butanoic acid, 4-[(2,5-dioxo-1-pyrrolidinyl)oxy]-4-oxo-3-[[(phenylmethoxy)carbonyl]amino]-, 1,1-dimethylethyl ester, (S)-
• N-Benzyloxycarbonyl-<span class="text-smallcaps">L</span>-aspartic acid 5-tert-butyl-1-hydroxysuccinimide diester
• Succinimide, N-[(N-carboxy-<span class="text-smallcaps">L</span>-α-aspartyl)oxy]-, N-benzyl tert-butyl ester
• Z-Asp(Otbu)-Osu
• Succinimide, N-[(N-carboxy-L-α-aspartyl)oxy]-, N-benzyl tert-butyl ester
• Aspartic acid, N-carboxy-, N-benzyl 4-tert-butyl ester, succinimido deriv., L-
• L-Aspartic acid, N-[(phenylmethoxy)carbonyl]-, 4-(1,1-dimethylethyl) 1-(2,5-dioxo-1-pyrrolidinyl) ester
• (S)-4-[(2,5-Dioxo-1-pyrrolidinyl)oxy]-4-oxo-3-[[(benzyloxy)carbonyl]amino]butyric acid tert-butyl ester
• Z-L-aspartic acid b-tert-butyl ester a-N-hydroxysuccinimide ester
• CBZ-Asp(OBut)-OSu
• O4-tert-butyl O1-(2,5-dioxopyrrolidin-1-yl) 2-(phenylmethoxycarbonylamino)butanedioate
• N-BENZYLOXYCARBONYL-L-ASPARTIC ACID 4-TERT-BUTYL-1-(N-SUCCINIMIDYL) ESTER
• N-Benzyloxycarbonyl-L-aspartic acid-4-tert-butyl-1- (N-hydroxysuccinimide)-
• 1-tert-butyl 2,5-dioxopyrrolidin-1-yl (3S)-3-{[(benzyloxy)carbonyl]amino}butanedioate
• tert-butyl (S)-4-[(2,5-dioxo-1-pyrrolidinyl)oxy]-4-oxo-3-[[(phenylmethoxy)carbonyl]amino]butyrate
• N-CBZ-beta-tert-butyl-L-aspartic acid N-hydroxysuccinimide
• 2-(benzyloxycarbonylamino)succinic acid O4-tert-butyl ester O1-succinimido ester
• Z-ASPARTIC ACID T-BUTYLESTER HYDROXYSUCCINIMIDESTER
• Z-L-Asp(OtBu)-OSu
• Z-L-Aspartic acid β-tert·butyl ester α- N-hydro
• CBZ-Asp(OtBu)-Osu
• Z-ASPARTIC ACID(OTBU)-OSU
• Z-L-ASPARTIC ACID 4-TERT-BUTYL-1-(N-SUCCINIMIDYL) ESTER
• Z-L-aspartic acid beta-tert-butyl ester beta-N-hydroxysucciniMide ester
• N-Cbz-β-t-butyl-L-aspartic acid N-hydroxysuccinimide ester, Z-L-aspartic acid 4-tert-butyl-1-(N-succinimidyl) ester
• Z-L-aspartic acid β-tert·butyl ester α-N-hydroxysuccinimide ester
• Z-ASP(OTBU)-OSU USP/EP/BP
• N-Benzyloxycarbonyl-L-aspartic acid 4-tert-butyl ester 1-(N-succinimidyl) ester
• 4-O-tert-butyl 1-O-(2,5-dioxopyrrolidin-1-yl) (2S)-2-(phenylmethoxycarbonylamino)butanedioate
• Z-ASPARTIC ACID TERT-BUTYL ESTER HYDROXYSUCCINIMIDE ESTER
• N-Cbz-β-t-butyl-L-aspartic acid N-hydroxysuccinimide ester
• N-CBZ-BETA-TERT-BUTYL-L-ASPARTIC ACID N-HYDROXYSUCCINIMIDE ESTER
• Z-ASP(OBUT)-OSU
• n-benzyloxycarbonyl-l-aspartic acid 4-tert-butyl 1-(n-succinimidyl)
• (S)-4-tert-Butyl 1-(2,5-dioxopyrrolidin-1-yl)-2-(((benzyloxy)carbonyl)amino)succinate
• N-CBZ-B-T-BUTYL-L-ASPARTIC ACIDN-HYDROXY SUCCINIMID
• CBZ-L-ASPARTIC ACID .BETA.-TERT-BUTYL ESTER .ALPHA.-N-HYDROXYSUCCINIMIDE ESTER
• Z-L-ASPARTIC ACID BETA-T-BUTYL ESTER ALPHA-N-HYDROXYSUCCINIMIDE ESTER
• Z-L-aspartic acid b-tert-butyl ester a-N-hydroxysuccinimide ester≥ 98% (HPLC)
• N-alpha-Benzyloxycarbonyl-L-aspartic acid alpha-(N-hydroxysuccinimidyl) beta-t-butyl ester
• N-(Benzyloxycarbonyl)-L-aspartic acid 1-succinimidyl 4-tert-butyl ester
• Z-L-ASPARTIC ACID 4-TERT-BUTYL-1-(N- &
• BENZYLOXYCARBONYL-L-ASPARTIC ACID BETA-T-BUTYL ESTER N-HYDROXYSUCCINIMIDE ESTER
• Z-L-Asp(tBu)-OSu
• BENZYLOXYCARBONYL-L-ASPARTIC ACID BETA-T-BUTYL-ALPHA-N-HYDROXYSUCCINIMIDE DI-ESTER
• N-cbz-B-T-butyl-L-aspartic acid*N-hydroxysuccinim

z-asp(otbu)-osu

CAS: 3338-32-7

Formula: C₂₀H₂₄N₂O₈

Purezza: 95%

Colore e forma: Solid

Peso molecolare: 420.4132

Ref: IN-DA00BYAG

(S)-4-tert-Butyl 1-(2,5-dioxopyrrolidin-1-yl) 2-(((benzyloxy)carbonyl)amino)succinate

CAS: 3338-32-7

(S)-4-tert-Butyl 1-(2,5-dioxopyrrolidin-1-yl) 2-(((benzyloxy)carbonyl)amino)succinate

Purezza: 95%

Peso molecolare: 420.42g/mol

Ref: 54-OR1070598

z-asp(otbu)-osu

CAS: 3338-32-7

Formula: C₂₀H₂₄N₂O₈

Purezza: 95%

Colore e forma: Solid

Peso molecolare: 420.418

Ref: 10-F045485