CAS 337376-15-5

Icodextrina

Descrizione:

Icodextrina è un carboidrato sintetico derivato dall'idrolisi enzimatica dell'amido, utilizzato principalmente in applicazioni mediche, in particolare nelle soluzioni per dialisi peritoneale. È un polimero di glucosio composto da varie lunghezze di catena, il che contribuisce alle sue proprietà uniche. Icodextrina è caratterizzato dalla sua capacità di creare un gradiente osmotico, facilitando l'eliminazione dell'eccesso di liquido dal corpo riducendo al minimo il rischio di complicazioni legate al glucosio. Viene tipicamente presentato come una soluzione chiara e incolore ed è noto per la sua biocompatibilità e bassa immunogenicità. La sostanza è stabile in condizioni normali e ha un peso molecolare relativamente basso, che consente un'assorbimento e un'escrezione efficienti. Inoltre, Icodextrina ha un basso valore calorico, rendendolo adatto per i pazienti che necessitano di gestione dei fluidi senza un'assunzione calorica significativa. Il suo utilizzo in contesti clinici è stato associato a migliori risultati per i pazienti in dialisi, in particolare in termini di ultrafiltrazione e bilancio dei fluidi. In generale, Icodextrina rappresenta un avanzamento significativo nella gestione dei pazienti sottoposti a dialisi peritoneale.

Formula: Unspecified

InChI: InChI=1/C46H62N4O11/c1-22(2)21-50-18-16-46(17-19-50)48-34-31-32-39(54)28(8)42-33(31)43(56)45(10,61-42)59-20-15-30(58-11)25(5)41(60-29(9)51)27(7)38(53)26(6)37(52)23(3)13-12-14-24(4)44(57)47-36(40(32)55)35(34)49-46/h12-15,20,22-23,25-27,30,37-38,41,49,52-54H,16-19,21H2,1-11H3,(H,47,57)/b13-12-,20-15-,24-14-/t23-,25-,26+,27+,30-,37-,38+,41-,45+/m1/s1

Sinonimi:

• (11beta,16beta)-9-fluoro-11,17,21-trihydroxy-16-methylpregna-1,4-diene-3,20-dione
• 3-methyl-4-oxo-3,4-dihydroimidazo[5,1-d][1,2,3,5]tetrazine-8-carboxamide
• A complex polyglucopyranose produced by the enzymatic hydrolysis of corn. It is primarily composed of alpha-1,4-glocopyranose linkage with less that 10 percent alpha-1,6 linkage
• platinum
• Adept (polysaccharide)
• 1-cyano-2-methyl-3-(2-{[(5-methyl-1H-imidazol-4-yl)methyl]sulfanyl}ethyl)guanidine
• (3S)-2-{N-[(2S)-1-ethoxy-1-oxo-4-phenylbutan-2-yl]-L-alanyl}-1,2,3,4-tetrahydroisoquinoline-3-carboxylic acid
• A complex alpha-D-glycopyranan produced by the enzymatic hydrolysis of corn. It is primarily composed of (1-4)-alpha-D-glucopyrano linkage with less than 10 percent (1-6)-alpha linkage. Dextrin, having more than 85% of its molecules with molecular masses between 1640 and 45,000 with a claimed-average molecular mass of approximately 20,000
• 2-(2,4-difluorophenyl)-1,3-di(1H-1,2,4-triazol-1-yl)propan-2-ol
• 1-ethyl-6-fluoro-4-oxo-7-(piperazin-1-yl)-1,4-dihydroquinoline-3-carboxylic acid
• [6-hydroxy-2-(4-hydroxyphenyl)-1-benzothiophen-3-yl]{4-[2-(piperidin-1-yl)ethoxy]phenyl}methanone
• 1-{2-[(7-chloro-1-benzothiophen-3-yl)methoxy]-2-(2,4-dichlorophenyl)ethyl}-1H-imidazole
• (11beta)-11,17,21-trihydroxypregna-1,4-diene-3,20-dione
• N-(piperidin-2-ylmethyl)-2,5-bis(2,2,2-trifluoroethoxy)benzamide
• azanide
• 2-(butan-2-yl)-4-{4-[4-(4-{[(2R,4S)-2-(2,4-dichlorophenyl)-2-(1H-1,2,4-triazol-1-ylmethyl)-1,3-dioxolan-4-yl]methoxy}phenyl)piperazin-1-yl]phenyl}-2,4-dihydro-3H-1,2,4-triazol-3-one
• A complex polyglucopyranose produced by the enzymatic hydrolysis of corn. It is primarily composed of alpha-1,4-glocopyranose linkage with less that 10 percent alpha-1,6 linkage
• 1-{amino[(4-chlorophenyl)amino]methylidene}-2-propan-2-ylguanidine
• (11beta,16beta)-9-chloro-11,17,21-trihydroxy-16-methylpregna-1,4-diene-3,20-dione
• 3-(5H-dibenzo[a,d][7]annulen-5-yl)-N-methylpropan-1-amine
• 3-[({2-[(diaminomethylidene)amino]-1,3-thiazol-4-yl}methyl)sulfanyl]-N'-sulfamoylpropanimidamide
• 2-phenyl-1H-indene-1,3(2H)-dione
• 1-[4-(4-{[(2S,4R)-2-(2,4-dichlorophenyl)-2-(1H-imidazol-1-ylmethyl)-1,3-dioxolan-4-yl]methoxy}phenyl)piperazin-1-yl]ethanone
• Icodextrin
• 2-benzyl-4,5-dihydro-1H-imidazole
• 5-ethyl-5-phenylpyrimidine-2,4,6(1H,3H,5H)-trione
• 1-methyl-1,3-dihydro-2H-imidazole-2-thione
• methyl (3beta,16beta,17alpha,18beta,20alpha)-11,17-dimethoxy-18-[(3,4,5-trimethoxybenzoyl)oxy]yohimban-16-carboxylate
• (6R,7R)-7-{[amino(phenyl)acetyl]amino}-3-chloro-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid
• 1-(9H-carbazol-4-yloxy)-3-{[2-(2-methoxyphenoxy)ethyl]amino}propan-2-ol
• 5-methyl-6-{[(3,4,5-trimethoxyphenyl)amino]methyl}quinazoline-2,4-diamine
• Icodial
• 2-(diethylamino)ethyl 1,1'-bi(cyclohexyl)-1-carboxylate
• N-(2,6-dimethylphenyl)-1-propylpiperidine-2-carboxamide
• 1-(1,2-benzoxazol-3-yl)methanesulfonamide
• 4-[4-(4-chlorophenyl)-4-hydroxypiperidin-1-yl]-1-(4-fluorophenyl)butan-1-one
• 6-chloro-3,4-dihydro-2H-1,2,4-benzothiadiazine-7-sulfonamide 1,1-dioxide
• (2S,5R,6R)-6-{[(2R)-2-amino-2-phenylacetyl]amino}-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid
• 1-methyl-3-phenylpyrrolidine-2,5-dione
• 5-chloro-1-{1-[3-(2-oxo-2,3-dihydro-1H-benzimidazol-1-yl)propyl]piperidin-4-yl}-1,3-dihydro-2H-benzimidazol-2-one
• Icodextrin, sodium chloride, sodium lactate, calcium chloride
• 1-chloro-2-[2,2-dichloro-1-(4-chlorophenyl)ethyl]benzene
• N,N-dimethyl-2-[(2-methylphenyl)(phenyl)methoxy]ethanamine
• 2-hydroxy-3-(3-oxo-1-phenylbutyl)-4H-chromen-4-one
• N~4~-(7-chloroquinolin-4-yl)-N~1~,N~1~-diethylpentane-1,4-diamine
• 2-(hydroxymethyl)-4-(1-hydroxy-2-{[6-(4-phenylbutoxy)hexyl]amino}ethyl)phenol
• 1-cyclohexyl-1-phenyl-3-(pyrrolidin-1-yl)propan-1-ol
• ethyl 4-(8-chloro-5,6-dihydro-11H-benzo[5,6]cyclohepta[1,2-b]pyridin-11-ylidene)piperidine-1-carboxylate
• (6R,7R)-3-[(carbamoyloxy)methyl]-7-{[(2E)-2-furan-2-yl-2-(methoxyimino)acetyl]amino}-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid
• 1,3-dibenzyl-2-oxodecahydrothieno[1',2':1,2]thieno[3,4-d]imidazol-5-ium
• 5-[bis(2-chloroethyl)amino]pyrimidine-2,4(1H,3H)-dione
• 5-[3-(tert-butylamino)-2-hydroxypropoxy]-3,4-dihydroquinolin-2(1H)-one
• N-methyl-3-phenyl-3-[4-(trifluoromethyl)phenoxy]propan-1-amine
• Adept
• 5-(3,4,5-trimethoxybenzyl)pyrimidine-2,4-diamine
• N,N-dimethyl-3-(10H-phenothiazin-10-yl)propan-1-amine
• Adept (polysaccharide)
• 3-(2-chloro-10H-phenothiazin-10-yl)-N,N-dimethylpropan-1-amine
• 2-methyl-6-oxo-1,6-dihydro-3,4'-bipyridine-5-carbonitrile
• ethyl 1-methyl-4-phenylpiperidine-4-carboxylate
• 7',12'-dihydroxy-6,6'-dimethoxy-2,2',2'-trimethyltubocuraran-2'-ium
• (2S,3aS,6aS)-1-[(2S)-2-{[(1S)-1-(ethoxycarbonyl)-3-phenylpropyl]amino}propanoyl]octahydrocyclopenta[b]pyrrole-2-carboxylic acid (non-preferred name)
• 2-amino-1-(2,5-dimethoxyphenyl)propan-1-ol
• N-[4-(acridin-9-ylamino)-3-methoxyphenyl]methanesulfonamide
• cyclobutane-1,1-dicarboxylic acid
• (5Z,7E,22E)-9,10-secoergosta-5,7,22-trien-3-ol
• 5,5-diphenylimidazolidine-2,4-dione
• 4-amino-N-(5-methyl-1,2-oxazol-3-yl)benzenesulfonamide
• 2-[(5-nitro-1,3-thiazol-2-yl)carbamoyl]phenyl acetate
• N,N,2-trimethyl-3-(10H-phenothiazin-10-yl)propan-1-amine
• Adept
• N,2,3,3-tetramethylbicyclo[2.2.1]heptan-2-amine
• 5-chloro-N-(4,5-dihydro-1H-imidazol-2-yl)-2,1,3-benzothiadiazol-4-amine
• (11beta,17beta)-11-[4-(dimethylamino)phenyl]-17-hydroxy-17-(prop-1-yn-1-yl)estra-4,9-dien-3-one
• (5alpha,6alpha)-17-methyl-7,8-didehydro-4,5-epoxymorphinan-3,6-diol
• 2-[(carbamoyloxy)methyl]-2-methylpentyl propan-2-ylcarbamate (non-preferred name)
• 2-chloro-N-(2-chloroethyl)-N-methylethanamine
• 3-ethyl-4-methyl-N-[2-(4-{[(4-methylcyclohexyl)carbamoyl]sulfamoyl}phenyl)ethyl]-2-oxo-2,5-dihydro-1H-pyrrole-1-carboxamide
• (17beta)-estra-1,3,5(10)-triene-3,17-diol
• 5-fluoropyrimidine-2,4(1H,3H)-dione
• methyl propan-2-yl 4-(2,1,3-benzoxadiazol-4-yl)-2,6-dimethyl-1,4-dihydropyridine-3,5-dicarboxylate
• 17,21-dihydroxypregna-1,4-diene-3,11,20-trione
• 3,7-dimethyl-1-(5-oxohexyl)-3,7-dihydro-1H-purine-2,6-dione
• 3-[(4-amino-2-methylpyrimidin-5-yl)methyl]-5-(2-hydroxyethyl)-4-methyl-1,3-thiazol-3-ium
• 2-[({5-methoxy-1-[4-(trifluoromethyl)phenyl]pentylidene}amino)oxy]ethanamine
• 2-{(Z)-[5-(hydroxymethyl)-3H-indol-3-ylidene]methyl}-N'-pentylhydrazinecarboximidamide
• [4-(4-amino-6,7-dimethoxyquinazolin-2-yl)piperazin-1-yl](2,3-dihydro-1,4-benzodioxin-2-yl)methanone
• 5-methyl-N-[4-(trifluoromethyl)phenyl]-1,2-oxazole-4-carboxamide
• 2-{4-[3-(2-chloro-10H-phenothiazin-10-yl)propyl]piperazin-1-yl}ethanol
• 4-(dipropylsulfamoyl)benzoic acid
• 1-[(2S)-2-methyl-3-sulfanylpropanoyl]-L-proline
• Extraneal
• (1S,3S)-3,5,12-trihydroxy-3-(hydroxyacetyl)-10-methoxy-6,11-dioxo-1,2,3,4,6,11-hexahydrotetracen-1-yl 3-amino-2,3,6-trideoxy-alpha-L-arabino-hexopyranoside
• (8R)-3-(2-deoxypentofuranosyl)-3,4,7,8-tetrahydroimidazo[4,5-d][1,3]diazepin-8-ol
• (4Z)-4-(3,3-dimethyltriazanylidene)-4H-imidazole-5-carboxamide
• 9-(beta-D-arabinofuranosyl)-9H-purin-6-amine hydrate (1:1)
• (1R,5R)-3-[(3-hydroxy-2-phenylpropanoyl)oxy]-8-methyl-8-(propan-2-yl)-8-azoniabicyclo[3.2.1]octane
• platinum(2+) ethanedioate - cyclohexane-1,2-diamine (1:1:1)
• 6-(5-chloropyridin-2-yl)-7-oxo-6,7-dihydro-5H-pyrrolo[3,4-b]pyrazin-5-yl 4-methylpiperazine-1-carboxylate
• 4-amino-N-[2-(diethylamino)ethyl]benzamide
• N,3-bis(2-chloroethyl)-1,3,2-oxazaphosphinan-2-amine 2-oxide
• 4-(2-{[4-(4-hydroxyphenyl)butan-2-yl]amino}ethyl)benzene-1,2-diol
• (1S,3R,7S,8S,8aR)-8-{2-[(2R,4R)-4-hydroxy-6-oxotetrahydro-2H-pyran-2-yl]ethyl}-3,7-dimethyl-1,2,3,7,8,8a-hexahydronaphthalen-1-yl 2,2-dimethylbutanoate
• 2-[benzyl(methyl)amino]ethyl methyl 2,6-dimethyl-4-(3-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylate
• (1S,3S)-3-acetyl-3,5,12-trihydroxy-6,11-dioxo-1,2,3,4,6,11-hexahydrotetracen-1-yl 3-amino-2,3,6-trideoxy-alpha-L-lyxo-hexopyranoside
• 4-{[(E)-(4-chlorophenyl)(3-fluoro-6-oxocyclohexa-2,4-dien-1-ylidene)methyl]amino}butanamide
• 3-ethyl-3-methylpyrrolidine-2,5-dione
• 4-(diethylamino)but-2-yn-1-yl cyclohexyl(hydroxy)phenylacetate
• (3S)-9,10-secocholesta-5,7,10-trien-3-ol
• 9-methyl-3-(2H-tetrazol-5-yl)-4H-pyrido[1,2-a]pyrimidin-4-one
• 2-[(1E)-1-(4-methylphenyl)-3-pyrrolidin-1-ylprop-1-en-1-yl]pyridine
• 4-chloro-N-(propylcarbamoyl)benzenesulfonamide
• (2S,5R,6R)-6-{[(2R)-2-{[(4-ethyl-2,3-dioxopiperazin-1-yl)carbonyl]amino}-2-phenylacetyl]amino}-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid
• 2-{3-[4-(3-chlorophenyl)piperazin-1-yl]propyl}-5-ethyl-4-(2-phenoxyethyl)-2,4-dihydro-3H-1,2,4-triazol-3-one
• (5alpha)-3,14-dihydroxy-17-methyl-4,5-epoxymorphinan-6-one
• N-[(1R)-1-(ethoxycarbonyl)-3-phenylpropyl]-L-alanyl-L-proline
• ethyl 1-(3-cyano-3,3-diphenylpropyl)-4-phenylpiperidine-4-carboxylate
• N~2~-[(1S)-1-carboxy-3-phenylpropyl]-L-lysyl-L-proline
• 5-{4-[(6-hydroxy-2,5,7,8-tetramethyl-3,4-dihydro-2H-chromen-2-yl)methoxy]benzyl}-1,3-thiazolidine-2,4-dione
• 6-phenylpteridine-2,4,7-triamine
• 3-(dibutylamino)-1-[1,3-dichloro-6-(trifluoromethyl)phenanthren-9-yl]propan-1-ol
• 1-{[(1Z)-(5-nitrofuran-2-yl)methylidene]amino}imidazolidine-2,4-dione
• ethyl methyl 2,6-dimethyl-4-(3-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylate
• 4-aminohex-5-enoic acid
• 2,2'-[(1R,2R,3S,4R,5R,6S)-4-({5-deoxy-2-O-[2-deoxy-2-(methylamino)-alpha-L-glucopyranosyl]-3-C-formyl-alpha-L-lyxofuranosyl}oxy)-2,5,6-trihydroxycyclohexane-1,3-diyl]diguanidine
• (6R,7R)-7-{[(2R)-2-amino-2-(4-hydroxyphenyl)acetyl]amino}-8-oxo-3-[(1E)-prop-1-en-1-yl]-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid
• 1-(beta-D-ribofuranosyl)-1H-1,2,4-triazole-3-carboxamide
• 2-[(5-nitrofuran-2-yl)methylidene]hydrazinecarboxamide
• 2-O-sulfohexopyranuronosyl-(1->4)-2-deoxy-3-O-sulfo-2-(sulfoamino)hexopyranosyl-(1->4)-2-O-sulfohexopyranuronosyl-(1->4)-2-(acetylamino)-2-deoxy-6-O-sulfohexopyranose
• 3-[(1R,2S)-2-amino-1-hydroxypropyl]phenol
• methyl (5S,7S,9S)-9-[(2beta,3beta,4beta,5alpha,12beta,19alpha)-3-carbamoyl-3,4-dihydroxy-16-methoxy-1-methyl-6,7-didehydroaspidospermidin-15-yl]-5-ethyl-5-hydroxy-1,4,5,6,7,8,9,10-octahydro-2H-3,7-methanoazacycloundecino[5,4-b]indole-9-carboxylate
• [2,3-dichloro-4-(2-methylidenebutanoyl)phenoxy]acetic acid
• (3S)-N-methyl-3-(naphthalen-1-yloxy)-3-(thiophen-2-yl)propan-1-amine
• 1-cyclopropyl-6-fluoro-4-oxo-7-(piperazin-1-yl)-1,4-dihydroquinoline-3-carboxylic acid
• 2,2'-hexane-1,6-diylbis(1-{amino[(4-chlorophenyl)amino]methylidene}guanidine)
• [(3aS,5aR,8aR,8bS)-2,2,7,7-tetramethyltetrahydro-3aH-bis[1,3]dioxolo[4,5-b:4',5'-d]pyran-3a-yl]methyl sulfamate (non-preferred name)
• (3E)-6-oxo-3-{[4-(pyridin-2-ylsulfamoyl)phenyl]hydrazono}cyclohexa-1,4-diene-1-carboxylic acid
• 5,5-dimethyl-3-[4-nitro-3-(trifluoromethyl)phenyl]imidazolidine-2,4-dione
• propan-2-yl 2-[4-(4-chlorobenzoyl)phenoxy]-2-methylpropanoate
• N,N-bis(2-chloroethyl)-1,3,2-oxazaphosphinan-2-amine 2-oxide
• 2,2'-[(1,4-dioxobutane-1,4-diyl)bis(oxy)]bis(N,N,N-trimethylethanaminium)
• 3-cyclohexyl-N,N,N-triethyl-3-hydroxy-3-phenylpropan-1-aminium
• 2-{4-[(1Z)-4-chloro-1,2-diphenylbut-1-en-1-yl]phenoxy}-N,N-dimethylethanamine
• [(3S)-3-{[(1S)-1-(ethoxycarbonyl)-3-phenylpropyl]amino}-2-oxo-2,3,4,5-tetrahydro-1H-1-benzazepin-1-yl]acetic acid
• (9S,12Z,14R,15R,16S,17S,18S,19S,20R,21R,22Z,24Z)-6,18,20-trihydroxy-14-methoxy-7,9,15,17,19,21,25-heptamethyl-1'-(2-methylpropyl)-5,10,26-trioxo-3,5,9,10-tetrahydrospiro[9,4-(epoxypentadeca[1,11,13]trienoimino)furo[2',3':7,8]naphtho[1,2-d]imidazole-2,4'-piperidin]-16-yl acetate
• 1-{4-[2-(cyclopropylmethoxy)ethyl]phenoxy}-3-(propan-2-ylamino)propan-2-ol
• 8-chloro-11-(4-methylpiperazin-1-yl)-10H-dibenzo[b,e][1,4]diazepine
• (1,8-diethyl-1,3,4,9-tetrahydropyrano[3,4-b]indol-1-yl)acetic acid
• (3Z)-3-[hydroxy(pyridin-2-ylamino)methylidene]-2-methyl-2,3-dihydro-4H-thieno[2,3-e][1,2]thiazin-4-one 1,1-dioxide
• 2'-deoxy-5-iodouridine
• (5alpha)-3,14-dihydroxy-17-prop-2-en-1-yl-4,5-epoxymorphinan-6-one
• 4-amino-1-[(2R,5S)-5-(hydroxymethyl)tetrahydrofuran-2-yl]pyrimidin-2(1H)-one
• 4-[(3-methylphenyl)amino]-N-(propan-2-ylcarbamoyl)pyridine-3-sulfonamide
• (1S)-1-{[(2S,3S)-3-hexyl-4-oxooxetan-2-yl]methyl}dodecyl N-formyl-L-leucinate
• 2-amino-9-[(2-hydroxyethoxy)methyl]-3,9-dihydro-6H-purin-6-one
• 4-amino-5-chloro-N-{1-[3-(4-fluorophenoxy)propyl]-3-methoxypiperidin-4-yl}-2-methoxybenzamide
• N-(2,6-dichlorophenyl)-4,5-dihydro-1H-imidazol-2-amine
• N-{3-[(4-amino-6,7-dimethoxyquinazolin-2-yl)(methyl)amino]propyl}tetrahydrofuran-2-carboxamide
• 5-chloro-1,3-benzoxazol-2(3H)-one
• 5-ethyl-3-methyl-5-phenylimidazolidine-2,4-dione
• (11E)-13-[(2S,3R,4R,5S)-3,4-dihydroxy-5-({(2R,3S)-3-[(1S,2S)-2-hydroxy-1-methylpropyl]oxiran-2-yl}methyl)tetrahydro-2H-pyran-2-yl]-12-methyl-10-oxotridec-11-enoic acid (non-preferred name)

Icodextrin

CAS: 337376-15-5

Purezza: 95%

Colore e forma: Solid

Peso molecolare: G/Mol

Ref: IN-DA0037O4