CAS 34183-22-7

Cloridrato di propafenone

Descrizione:

Cloridrato di propafenone è un composto farmaceutico utilizzato principalmente come agente antiaritmico per il trattamento di alcuni tipi di battiti cardiaci irregolari, specificamente fibrillazione atriale e tachicardia ventricolare. È classificato come un farmaco antiaritmico di Classe IC, il che significa che agisce bloccando i canali del sodio nelle cellule cardiache, stabilizzando così la membrana cardiaca e riducendo l'eccitabilità. La sostanza appare come una polvere cristallina bianca a bianco sporco ed è solubile in acqua e alcol, il che facilita la sua formulazione in varie forme di dosaggio, come compresse e soluzioni orali. Cloridrato di propafenone è noto per la sua capacità di prolungare il periodo refrattario nei tessuti cardiaci, aiutando così a ripristinare il normale ritmo cardiaco. Può anche presentare proprietà beta-bloccanti, contribuendo ai suoi effetti terapeutici. Gli effetti collaterali comuni possono includere vertigini, affaticamento e disturbi gastrointestinali. A causa del suo profilo farmacologico, è necessario un attento monitoraggio durante il trattamento, specialmente nei pazienti con condizioni cardiache preesistenti o quelli che assumono altri farmaci che possono interagire con il suo metabolismo.

Formula: C₂₁H₂₇NO₃·ClH

InChI: InChI=1S/C21H27NO3.ClH/c1-2-14-22-15-18(23)16-25-21-11-7-6-10-19(21)20(24)13-12-17-8-4-3-5-9-17;/h3-11,18,22-23H,2,12-16H2,1H3;1H

InChI key: InChIKey=XWIHRGFIPXWGEF-UHFFFAOYSA-N

SMILES: O(CC(CNCCC)O)C1=C(C(CCC2=CC=CC=C2)=O)C=CC=C1.Cl

Sinonimi:

• 1-(2-(2-Hydroxy-3-(propylamino)propoxy)phenyl)-3-phenylpropan-1-one hydrochloride
• 1-Propanone, 1-(2-(2-hydroxy-3-(propylamino)propoxy)phenyl)-3-phenyl-, hydrochloride
• 1-Propanone, 1-[2-[2-hydroxy-3-(propylamino)propoxy]phenyl]-3-phenyl-, hydrochloride (1:1)
• 1-{2-[2-Hydroxy-3-(Propylamino)Propoxy]Phenyl}-3-Phenylpropan-1-One Hydrochloride (1:1)
• 2'-(2-Hydroxy-3-(propylamino)propoxy)-3-phenylpropiophenone hydrochloride
• Arythmol
• Baxarytmon
• Fenoprain
• Pronon
• Propafenon hydrochlorid
• Propafenon hydrochlorid [German]
• Propafenone hydrochloride
• Propafenone hydrochloride [USAN:JAN]
• Propiophenone, 2'-(2-hydroxy-3-(propylamino)propoxy)-3-phenyl-, hydrochloride
• Rhythmonorm
• Rythmol
• Rythmol SR
• Rytmonorm
• Sa 79
• Unii-33Xch0Hocd
• Wz 884
• 2’-(2-hydroxy-3-(propylamino)propoxy)-3-phenyl-propiophenonhydrochloride
• 1-Propanone, 1-[2-[2-hydroxy-3-(propylamino)propoxy]phenyl]-3-phenyl-, hydrochloride (9CI)
• Rytmonor
• 1-(2-(2-hydroxy-3-(propylamino)propoxy)phenyl)-3-phenyl-1-propanonhydroc
• 1-[2-(2-HYDROXY-3-[PROPYLAMINO]-PROPOXY)PHENYL]-3-PHENYL-1-PROPANONE HYDROCHLORIDE
• 2’-(2-hydroxy-3-(propylamino)propoxy)-3-phenylpropiophenonehydrochloride
• PROPAFENONE HCL
• sa79
• Propiophenone, 2'-[2-hydroxy-3-(propylamino)propoxy]-3-phenyl-, hydrochloride (8CI)
• wz884

Propafenone Hydrochloride

CAS: 34183-22-7, 54063-53-5

Formula: C₂₁H₂₇NO₃·HCl

Purezza: >98.0%(T)(HPLC)

Colore e forma: White to Almost white powder to crystal

Peso molecolare: 377.91

Ref: 3B-P2301

Propafenone Hydrochloride

CAS: 34183-22-7

Colore e forma: Neat

Ref: 61-FOR0405.00

PROPAFENONE HYDROCHLORIDE CRS

CAS: 34183-22-7

PROPAFENONE HYDROCHLORIDE CRS

Formula: C₂₁H₂₈ClNO₃

Colore e forma: White. Colourless Crystals. Powder.

Peso molecolare: 377.9049

Ref: 41-Y0000455

Propafenone Hydrochloride

CAS: 34183-22-7

Aromatic amino-alcohol-phenols, aromatic amino-acid-phenols and other aromatic amino compounds with oxygen function

Formula: C₂₁H₂₇NO₃·ClH

Colore e forma: Colorless White Powder

Peso molecolare: 377.17577

Ref: 45-1570304

1-{2-[2-hydroxy-3-(propylamino)propoxy]phenyl}-3-phenylpropan-1-one hydrochloride

CAS: 34183-22-7

Formula: C₂₁H₂₈ClNO₃

Purezza: 95%

Colore e forma: Solid

Peso molecolare: 377.9049

Ref: IN-DA00391F

Propafenone HCl

CAS: 34183-22-7

Formula: C₂₁H₂₇NO₃·HCl

Colore e forma: White To Off-White Solid

Peso molecolare: 341.45 36.46

Ref: 4Z-P-1512

Propafenone hydrochloride

CAS: 34183-22-7

Propafenone hydrochloride

Purezza: ≥98%

Peso molecolare: 377.9g/mol

Ref: 54-BUP17652

1-[2-[2-Hydroxy-3-(Propylamino)Propoxy]Phenyl]-3-Phenylpropan-1-One Hydrochloride

CAS: 34183-22-7

1-[2-[2-Hydroxy-3-(Propylamino)Propoxy]Phenyl]-3-Phenylpropan-1-One Hydrochloride

Purezza: 98%

Peso molecolare: 377.9g/mol

Ref: 54-OR1030254

Propafenone hydrochloride, 10mM (in DMSO)

CAS: 34183-22-7

Propafenone hydrochloride, 10mM (in DMSO)

Purezza: ≥98%

Peso molecolare: 377.9g/mol

Ref: 54-BUP20003

Propafenone hydrochloride

CAS: 34183-22-7

Formula: C₂₁H₂₇NO₃·HCl

Purezza: 98.0 - 102.0 % (C21H27NO3 · HCl, dried basis)

Colore e forma: Colourless crystals or white crystalline powder

Peso molecolare: 377.90

Ref: 7W-GP3270

Propafenone Hydrochloride

CAS: 34183-22-7

Formula: C₂₁H₂₇NO₃·ClH

Colore e forma: Neat

Peso molecolare: 377.90

Ref: 86-MM0405.00

Propafenone hydrochloride

CAS: 34183-22-7

Formula: C₂₁H₂₇NO₃·ClH

Colore e forma: Neat

Peso molecolare: 377.90

Ref: 04-C16385000

Propafenone hydrochloride

CAS: 34183-22-7

Propafenone hydrochloride (Arythmol8) is a classic anti-arrhythmic medication, which treats illnesses associated with rapid heartbeats such as atrial.

Formula: C₂₁H₂₇NO₃·HCl

Purezza: 99.67%

Colore e forma: White Solid

Peso molecolare: 377.9

Ref: TM-T6955

Propafenone Hydrochloride

Prodotto controllato

CAS: 34183-22-7

Applications Sodium channel blocker. Antiarrhythmic (class IC).
References Hollmann, M., et al.: Arzneim.-Forsch., 33, 763 (1983), Bryson, H. M., et al.:Drugs, 45, 85 (1993), Rae, A. P., et al.: Am. J. Cardiol., 82, 59N (1998),

Formula: C₂₁H₂₇NO₃·ClH

Colore e forma: White To Off-White

Peso molecolare: 377.90

Ref: TR-P757500

Propafenone HCl - Bio-X ™

CAS: 34183-22-7

This product is part of our Bio-X ™ Range. These products are aimed at life science researchers who need high quality ready-to-use products for assay development, screening or other R&D work. With a solubility datasheet and convenient vials, all of our Bio-X ™ products are in stock across our global warehouses for rapid delivery and ease of use.

Formula: C₂₁H₂₈ClNO₃

Purezza: Min. 95%

Colore e forma: Powder

Peso molecolare: 377.9 g/mol

Ref: 3D-BP300114

1-{2-[2-hydroxy-3-(propylamino)propoxy]phenyl}-3-phenylpropan-1-one hydrochloride

CAS: 34183-22-7

Formula: C₂₁H₂₈ClNO₃

Purezza: 95%+

Peso molecolare: 377.91

Ref: 10-F358367

Propafenone HCl

CAS: 34183-22-7

Propafenone HCl is a class Ia antiarrhythmic drug that is used to treat atrial fibrillation and other cardiac arrhythmias. It has a high solubility in water, which makes it suitable for intravenous administration. The binding constants of propafenone to the cardiac muscle and myocardial cells are relatively high. This drug has also been shown to be safe in pediatric patients with congestive heart failure. Propafenone HCl has been shown to have an adverse effect on some people, causing serious side effects such as congestive heart failure or hypersensitivity reactions.

Formula: C₂₁H₂₈ClNO₃

Purezza: Min. 95%

Colore e forma: White Powder

Peso molecolare: 377.9 g/mol

Ref: 3D-FP27186