CAS 34298-86-7

Rhein 8-O-β-D-glucopiranoside

Descrizione:

Rhein 8-O-β-D-glucopiranoside è un composto glicosidico derivato dalla rhein, che è un'antraquinone naturale presente in varie piante, in particolare nelle specie di rabarbaro. Questo composto presenta un gruppo glucopiranosidico, indicando che è costituito da una molecola di glucosio legata alla struttura della rhein tramite un legame glicosidico. Rhein 8-O-β-D-glucopiranoside è noto per le sue potenziali proprietà farmacologiche, comprese attività antinfiammatorie, antiossidanti e anticancro. È solubile in acqua e mostra stabilità in diverse condizioni di pH, rendendolo adatto per applicazioni biologiche. La struttura del composto contribuisce alla sua bioattività, poiché la glicosilazione può migliorare la solubilità e modulare l'interazione con obiettivi biologici. Inoltre, la ricerca sui suoi meccanismi d'azione e sul potenziale terapeutico è in corso, evidenziando la sua rilevanza nella chimica medicinale e nella ricerca di prodotti naturali. In generale, Rhein 8-O-β-D-glucopiranoside rappresenta un composto significativo di interesse nello studio delle sostanze derivate dalle piante e dei loro benefici per la salute.

Formula: C₂₁H₁₈O₁₁

InChI: InChI=1S/C21H18O11/c22-6-12-16(25)18(27)19(28)21(32-12)31-11-3-1-2-8-14(11)17(26)13-9(15(8)24)4-7(20(29)30)5-10(13)23/h1-5,12,16,18-19,21-23,25,27-28H,6H2,(H,29,30)/t12-,16-,18+,19-,21-/m1/s1

InChI key: InChIKey=WYKUTTFFZMQCGO-HTRBZNBPSA-N

SMILES: O(C1=C2C(C(=O)C=3C(C2=O)=C(O)C=C(C(O)=O)C3)=CC=C1)[C@@H]4O[C@H](CO)[C@@H](O)[C@H](O)[C@H]4O

Sinonimi:

• 2-Anthracenecarboxylic acid, 5-(β-<span class="text-smallcaps">D</span>-glucopyranosyloxy)-9,10-dihydro-4-hydroxy-9,10-dioxo-
• 2-Anthroic acid, 5-(β-<span class="text-smallcaps">D</span>-glucopyranosyloxy)-9,10-dihydro-4-hydroxy-9,10-dioxo-
• 2-Anthroicacid, 5-(b-D-glucopyranosyloxy)-9,10-dihydro-4-hydroxy-9,10-dioxo-(8CI)
• 5-(β-<span class="text-smallcaps">D</span>-Glucopyranosyloxy)-9,10-dihydro-4-hydroxy-9,10-dioxo-2-anthracenecarboxylic acid
• 8-Glucosidorhein-9-anthrone
• 8-Glucosylrhein
• Glucorein
• Glucorhein
• Glucorhein (7CI)
• Rhein 8-O-glucoside
• Rhein 8-O-β-<span class="text-smallcaps">D</span>-glucopyranoside
• Rhein-8-glucoside
• 5-(β-D-Glucopyranosyloxy)-9,10-dihydro-4-hydroxy-9,10-dioxo-2-anthracenecarboxylic acid
• 2-Anthracenecarboxylic acid, 5-(β-D-glucopyranosyloxy)-9,10-dihydro-4-hydroxy-9,10-dioxo-

2-Anthracenecarboxylic acid,5-(b-D-glucopyranosyloxy)-9,10-dihydro-4-hydroxy-9,10-dioxo-

CAS: 34298-86-7

Formula: C₂₁H₁₈O₁₁

Purezza: 98%

Colore e forma: Solid

Peso molecolare: 446.3610

Ref: IN-DA00BZA9

Rhein-8-glucoside

CAS: 34298-86-7

Formula: C₂₁H₁₈O₁₁

Peso molecolare: 446.36

Ref: 7W-GY7023

Rhein 8-Glucoside

CAS: 34298-86-7

Rhein 8-Glucoside

Purezza: ≥95%

Peso molecolare: 446.36g/mol

Ref: 54-BUP03021

Rhein-8-glucoside

CAS: 34298-86-7

Formula: C₂₁H₁₈O₁₁

Purezza: 95%~99%

Peso molecolare: 446.364

Ref: BP-BP1527

Rhein 8-Glucoside

CAS: 34298-86-7

Rhein 8-Glucoside (Rhein-8-glucoside) has low laxative activity.

Formula: C₂₁H₁₈O₁₁

Purezza: 96.11% - 99.71%

Colore e forma: Solid

Peso molecolare: 446.36

Ref: TM-TN2154

Rhein 8-O-β-D-Glucoside

CAS: 34298-86-7

Formula: C₂₁H₁₈O₁₁

Peso molecolare: 446.36

Ref: 4Z-R-2817

Rhein 8-glucoside

CAS: 34298-86-7

Natural glycoside

Formula: C₂₁H₁₈O₁₁

Purezza: ≥ 95.0 % (HPLC)

Colore e forma: Powder

Peso molecolare: 446.37

Ref: 5G-83536

Rhein 8-Glucoside

Prodotto controllato

CAS: 34298-86-7

Applications Rhein 8-Glucoside has been seen to exhibit cytotoxic and DNA-damaging properties towards tumor and normal human cells. In addition it has been shown to be an inhibitor of PTP1B (Human Protein Tyrosine Kinase 1B) in vitro. It is an analog of Rhein (R318500) which is found in the free state and as glucoside in Rheum spp, Polygonaceae (rhubarb) and in Senna leaves. It is a potential antioxidant resource: endophytic fungi from medicinal plants.
References Wanitschke, Pharmacology, 20, Suppl. 1, 21 (1980); Raimondi, L., et al.: Pharmacol. Res. Commun., 14, 103 (1982); Franchi-Micheli, S., et al.: J. Pharm. Pharmacol., 35, 262 (1983); Li, S. et al.: J. Asian Nat. Prod. Res., 8, 281 (2006); Shi, Y.Q. et al.: Anticancer. Res., 21, 2847 (2001);

Formula: C₂₁H₁₈O₁₁

Colore e forma: Neat

Peso molecolare: 446.36

Ref: TR-R318520

Rhein-8-glucoside

CAS: 34298-86-7

Rhein-8-glucoside is a naturally occurring anthraquinone glycoside, which is derived primarily from the roots of plants such as Rheum species. These plants have been traditionally used in herbal medicine, and the glycoside form of Rhein enhances its solubility and bioavailability. The mode of action of Rhein-8-glucoside involves the modulation of various cellular pathways, including the inhibition of specific enzymes and the interaction with cellular receptors, potentially leading to anti-inflammatory, antioxidant, and antimicrobial effects.

Formula: C₂₁H₁₈O₁₁

Purezza: Min. 95%

Colore e forma: Powder

Peso molecolare: 446.36 g/mol

Ref: 3D-FR65510

Rhein 8-Glucoside

CAS: 34298-86-7

Formula: C₂₁H₁₈O₁₁

Peso molecolare: 446.36

Ref: ST-EA-CP-S57004