CAS 343-65-7

Chinurenina

Descrizione:

Chinurenina è un metabolita endogeno dell'aminoacido triptofano, che svolge un ruolo significativo in vari processi biologici. È principalmente coinvolto nella via di Chinurenina, che è cruciale per il metabolismo del triptofano e la produzione di diversi composti neuroattivi. Chinurenina è caratterizzato dalla sua struttura, che include un anello indolico e una catena laterale contenente un acido carbossilico e un gruppo amminico. Questo composto presenta una gamma di attività biologiche, inclusi effetti neuroprotettivi e neurotossici, a seconda della sua concentrazione e della presenza di altri metaboliti nella via di Chinurenina. Chinurenina è anche implicato nella regolazione della risposta immunitaria ed è stato studiato per il suo potenziale ruolo in vari disturbi neurologici, tra cui depressione e malattie neurodegenerative. La sua solubilità in acqua e in vari solventi organici consente diverse applicazioni nella ricerca biochimica. Inoltre, Chinurenina può essere misurato in campioni biologici, rendendolo un biomarcatore prezioso per valutare condizioni metaboliche e patologiche.

Formula: C₁₀H₁₂N₂O₃

InChI: InChI=1S/C10H12N2O3/c11-7-4-2-1-3-6(7)9(13)5-8(12)10(14)15/h1-4,8H,5,11-12H2,(H,14,15)

InChI key: InChIKey=YGPSJZOEDVAXAB-UHFFFAOYSA-N

SMILES: C(CC(C(O)=O)N)(=O)C1=C(N)C=CC=C1

Sinonimi:

• 2-Amino-4-(2-Aminophenyl)-4-Oxobutanoic Acid
• 2-Amino-4-(2-aminophenyl)-4-oxobutanoicacid
• 3-Anthraniloyl-<span class="text-smallcaps">D</smallcap><smallcap>L</span>-alanine
• 3-Anthraniloylalanine
• <span class="text-smallcaps">DL</span>-Kynurenine
• Alanine, 3-anthraniloyl-
• Benzenebutanoic acid, α,2-diamino-γ-oxo-
• Beta-Anthraniloyl-Alpha-Alanine
• Dl-Kynurenine Free Base
• Kynurenin
• Kynurenine

DL-Kynurenine

CAS: 343-65-7

Formula: C₁₀H₁₂N₂O₃

Purezza: 98%

Colore e forma: Solid

Peso molecolare: 208.2139

Ref: IN-DA00BYZG

Kynurenine

CAS: 343-65-7

Formula: C₁₀H₁₂N₂O₃

Peso molecolare: 208.22

Ref: 4Z-K-008003

2-Amino-4-(2-aminophenyl)-4-oxobutanoic acid

CAS: 343-65-7

2-Amino-4-(2-aminophenyl)-4-oxobutanoic acid

Purezza: ≥98%

Peso molecolare: 208.21g/mol

Ref: 54-BUP14242

DL-Kynurenine

CAS: 343-65-7

Ref: 7W-GM2236

DL-Kynurenine-d7 (2,3,3-d3 ;ring-d4)

CAS: 343-65-7

Purezza: 99 atom % D

Peso molecolare: 215.26

Ref: 3U-D8212

2-Amino-4-(2-aminophenyl)-4-oxobutanoic acid

CAS: 343-65-7

2-Amino-4-(2-aminophenyl)-4-oxobutanoic acid: a vasodilator, immunomodulator, neuromodulator, niacin precursor, and potential cancer biomarker.

Formula: C₁₀H₁₂N₂O₃

Purezza: 99.04% - 99.66%

Colore e forma: Solid

Peso molecolare: 208.21

Ref: TM-T3011

rac Kynurenine

Prodotto controllato

CAS: 343-65-7

Applications A tryptophan metabolite, is a precursor of kynurenic acid, which is an antagonist of N-methyl-aspartate receptor. An amino acid produced in the body from tryptophan.
References Swartz, K., et al.: J. Neurosci., 10, 2965 (1990), Hasegawa, H., et al.: Anal. Bioanal. Chem., 377, 886 (2003), Tsai, Y., et al.: Anal. Biochem., 319, 34 (2003), Mitsuhashi, S., et al.: Anal. Chim. Acta, 584, 315 (2007),

Formula: C₁₀H₁₂N₂O₃

Colore e forma: Neat

Peso molecolare: 208.21

Ref: TR-K661000

rac Kynurenine-d4 Trifluoroacetic Acid Salt (Major)

Prodotto controllato

CAS: 343-65-7

Stability Hygroscopic
Applications rac Kynurenine-d4 Trifluoroacetic Acid Salt is the isotope labelled analog of rac Kynurenine (K661000) which is a tryptophan metabolite.
References Swartz, K., et al.: J. Neurosci., 10, 2965 (1990), Hasegawa, H., et al.: Anal. Bioanal. Chem., 377, 886 (2003), Tsai, Y., et al.: Anal. Biochem., 319, 34 (2003), Mitsuhashi, S., et al.: Anal. Chim. Acta, 584, 315 (2007),

Formula: C₁₀H₈D₄N₂O₃•x(C₂HF₃O₂)

Colore e forma: Neat

Peso molecolare: 212.2411402

Ref: TR-K661003

DL-Kynurenine, free base

CAS: 343-65-7

DL-Kynurenine, free base is an amino acid that is a product of the normal catabolic pathway for tryptophan. It is also present in some foods and may be produced endogenously from tryptophan or kynurenine. DL-Kynurenine is used as a polymerase chain reaction (PCR) substrate to detect enterovirus RNA and has been shown to be effective against bowel disease in vitro. DL-Kynurenine has been studied as a potential pharmacological agent for the treatment of inflammatory diseases such as rheumatoid arthritis, Crohn's disease, ulcerative colitis, and psoriasis. DL-Kynurenine binds to toll-like receptor 4 (TLR4) and inhibits picolinic acid production by macrophages. This leads to decreased matrix metalloproteinase activity and energy metabolism, which may have a protective effect on neuronal death by reducing oxidative stress.

Formula: C₁₀H₁₂N₂O₃

Purezza: Min. 95%

Peso molecolare: 208.20 g/mol

Ref: 3D-FK172296

DL-Kynurenine, free base

CAS: 343-65-7

DL-Kynurenine is a versatile building block, useful in the synthesis of complex compounds. The compound has been used as a reagent, and as a speciality chemical with high quality. DL-Kynurenine can be used as a starting material for the synthesis of other chemicals, such as pharmaceuticals or pesticides. It can also be used as an intermediate to produce drugs that are useful for the treatment of Alzheimer's disease, Huntington's disease, Parkinson's disease and schizophrenia. DL-Kynurenine is also an effective scaffold for drug design.

Formula: C₁₀H₁₂N₂O₃

Purezza: Min. 95 Area-%

Peso molecolare: 208.22 g/mol

Ref: 3D-K-9000

2-Amino-4-(2-aminophenyl)-4-oxobutanoic acid

CAS: 343-65-7

Formula: C₁₀H₁₂N₂O₃

Purezza: 98%

Peso molecolare: 208.217

Ref: 10-F223134