CAS 34346-01-5

Acido polilattico-co-glicolico

Descrizione:

Acido polilattico-co-glicolico (PLGA) è un copolimero biodegradabile composto da monomeri di acido lattico e acido glicolico. È caratterizzato dalla sua biocompatibilità, rendendolo adatto per varie applicazioni biomediche, inclusi sistemi di somministrazione di farmaci, ingegneria dei tessuti e suture. Le proprietà del PLGA possono essere adattate modificando il rapporto tra acido lattico e acido glicolico, il che influisce sulla sua velocità di degradazione e resistenza meccanica. Tipicamente, il PLGA presenta una temperatura di transizione vetrosa che consente di rimanere flessibile a temperature fisiologiche. La degradazione del PLGA avviene attraverso idrolisi, portando al rilascio graduale dei farmaci incapsulati o alla scomposizione del polimero in sottoprodotti non tossici, principalmente acidi lattico e glicolico, che sono metabolizzati naturalmente dal corpo. Inoltre, il PLGA può essere lavorato in varie forme, come microsfere, film e impalcature, aumentando la sua versatilità nelle applicazioni mediche. La sua approvazione da parte della FDA per l'uso in dispositivi medici sottolinea ulteriormente la sua sicurezza ed efficacia in contesti clinici.

Formula: (C₃H₆O₃·C₂H₄O₃)x

InChI: InChI=1S/C3H6O3.C2H4O3/c1-2(4)3(5)6;3-1-2(4)5/h2,4H,1H3,(H,5,6);3H,1H2,(H,4,5)

InChI key: InChIKey=XBBVURRQGJPTHH-UHFFFAOYSA-N

SMILES: C(CO)(O)=O.C(C(O)=O)(C)O

Sinonimi:

• (.+-.)-2-Hydroxypropanoic acid-hydroxyacetic acid copolymer
• 2-Hydroxyacetic acid-lactic acid copolymer
• 85Dg065
• <span class="text-smallcaps">D</smallcap><smallcap>L</span>-Lactic acid-glycolic acid copolymer
• Acetic acid, hydroxy-, polymer with 2-hydroxypropanoic acid
• Alzamer Depot
• B 6006-1P
• Expansorb DLG 50-2A
• GC-Membrane
• Glycolic acid-<span class="text-smallcaps">D</smallcap><smallcap>L</span>-lactic acid copolymer
• Glycolic acid-DL-lactic acid copolymer
• Glycolic acid-lactic acid copolymer
• Glycolic acid-lactic acid polymer
• Glycolic acid-lactid acid copolymer
• Hydroxyacetic acid-(.+-.)-2-hydroxypropanoic acid copolymer
• Hydroxyacetic acid-2-hydroxypropionic acid copolymer
• Hydroxyacetic acid-lactic acid copolymer
• Lactel BP 400
• Lactic acid-glycolic acid copolymer
• Lactic acid-glycolic acid polymer
• Lactic acid-hydroxyacetic acid copolymer
• Lg 80
• Lg 855S
• M 700 (polyester)
• Medisorb 5050DL1A
• P 134386-1G
• Plga 5-1
• Plga 5-50
• Plga 5005
• Plga 5010
• Plga 5015
• Plga 5020
• Plga 75-65
• Plga 7505
• Plga 7510
• Plga 7515
• Plga 7520
• Plga 7525
• Plga 7525-4A
• Plga 7525-5A
• Poly(<span class="text-smallcaps">D</smallcap><smallcap>L</span>-lactic acid-co-glycolic acid)
• Poly(<span class="text-smallcaps">D</smallcap><smallcap>L</span>-lactic acid-glycolic acid)
• Poly(<span class="text-smallcaps">D</smallcap><smallcap>L</span>-lactic-co-glycolic acid)
• Poly(DL-lactic acid-glycolic acid)
• Poly(d,l-lactic-co-glycolic acid)
• Poly(glycolic acid-co-<span class="text-smallcaps">D</smallcap><smallcap>L</span>-lactic acid)
• Poly(glycolic acid-co-DL-lactic acid)
• Poly(glycolic acid-lactic acid)
• Poly(lactic acid-co-glycolic acid)
• Poly(lactic acid-glycolic acid)
• Poly(lactic acid-hydroxyacetic acid) copolymer
• Poly(lactic-co-glycolic acid)
• Polylactic acid-glycolic acid copolymer
• Polylactoglycolidic acid
• Propanoic acid, 2-hydroxy-, polymer with 2-hydroxyacetic acid
• Purasorb PDLG 5002
• Purasorb PDLG 5002A
• Purasorb PLG 8531
• Resolut
• Resolut LT
• Resolut ST
• Resomer 753S
• Resomer LG 824S
• Resomer LG 855S
• Resomer RG 756S
• Resomer RG 858
• dl-Lactic acid-glycolic acid copolymer
• dl-Lactic acid-glycolic acid polymer

PLGA 75:25 DLLAGA 2A (Poly(DL-lactic acid-co-glycolic acid) acid terminated (75:25))

CAS: 34346-01-5

Polyesters, saturated, in primary forms, nesoi

Formula: HC₃H₄O₂nC₂H₂O₂mOH

Colore e forma: White Powder

Peso molecolare: 4.000-15.000 Da

Ref: 45-1800101

PLGA

CAS: 34346-01-5

PLGA (poly(lactic-co-glycolic acid)) is be used to fabricate devices for drug delivery and tissue engineering applications.

Formula: (C₃H₆O₃·C₂H₄O₃)x

Purezza: 50:50 - 50:50

Colore e forma: Solid

Peso molecolare: 166.129

Ref: TM-T19521

PLGA

CAS: 34346-01-5

PLGA is a biocompatible polymer that is used in the manufacture of implantable medical devices. It is also used as an injection solution and has significant cytotoxicity. PLGA has been shown to be effective in vivo in animal models with breast cancer, hypoglycemia, and bone-disease implants. In vitro studies have confirmed its efficacy as a delivery vehicle for growth factor-β1. Furthermore, PLGA nanoparticles are being investigated as a drug-delivery system for radiation therapy.

Formula: (C₃H₆O₃)n•(C₂H₄O₃)n

Purezza: Min 98%

Colore e forma: Powder

Ref: 3D-FP166703

PLGA(50:50)

CAS: 34346-01-5

Please enquire for more information about PLGA(50:50) including the price, delivery time and more detailed product information at the technical inquiry form on this page

Formula: (C₃H₆O₃•C₂H₄O₃)x

Ref: 3D-FP184493