CAS 34604-60-9

Acido 5-idrossipirazina-2-carbossilico

Descrizione:

Acido 5-idrossipirazina-2-carbossilico, con il numero CAS 34604-60-9, è un composto organico caratterizzato dalla sua struttura ad anello di pirazina, che è un anello aromatico a sei membri contenente due atomi di azoto. Questo composto presenta un gruppo idrossile (-OH) e un gruppo acido carbossilico (-COOH) attaccati all'anello di pirazina, contribuendo alla sua natura polare e al potenziale per legami idrogeno. È tipicamente un solido cristallino bianco a bianco sporco, solubile in acqua e vari solventi organici, il che ne aumenta l'utilità nelle reazioni chimiche e nelle formulazioni. La presenza di entrambi i gruppi funzionali consente una reattività diversificata, rendendolo un intermediario prezioso nella sintesi organica, in particolare nello sviluppo di farmaci e agrochimici. Inoltre, la sua attività biologica può includere proprietà antiossidanti, sebbene le applicazioni specifiche possano variare. Come per molti composti organici, la manipolazione deve essere effettuata con cautela, seguendo i protocolli di sicurezza appropriati per mitigare eventuali pericoli potenziali associati al suo uso.

Formula: C₅H₄N₂O₃

InChI: InChI=1S/C5H4N2O3/c8-4-2-6-3(1-7-4)5(9)10/h1-2H,(H,7,8)(H,9,10)

InChI key: InChIKey=CGQFCIHUUCMACC-UHFFFAOYSA-N

SMILES: C(O)(=O)C1=CNC(=O)C=N1

Sinonimi:

• 2-Pyrazinecarboxylic acid, 4,5-dihydro-5-oxo-
• 4,5-Dihydro-5-oxo-2-pyrazinecarboxylic acid
• 5-Hydropyrazine-2-Carboxylic Acid
• 5-Hydroxy-2-Pyrazinecarboxylic Acid
• 5-Hydroxy-Pyrazine-2-Carboxylic Acid
• 5-Hydroxypyrazine-2-Carboxylic Acid
• 5-Hydroxypyrazinoic Acid
• 5-Oxo-4,5-dihydropyrazine-2-carboxylic acid
• Pyrazinecarboxylic Acid, 4,5-Dihydro-5-Oxo-
• Pyrazinecarboxylic acid, 5-hydroxy-

5-Hydroxypyrazine-2-Carboxylic Acid

CAS: 34604-60-9

Formula: C₅H₄N₂O₃

Purezza: 98%

Colore e forma: Solid

Peso molecolare: 140.0969

Ref: IN-DA00BZJ0

5-Hydroxypyrazine-2-Carboxylic Acid

CAS: 34604-60-9

5-Hydroxypyrazine-2-Carboxylic Acid is a metabolite of anti-tuberculosis drug pyrazinamide.

Formula: C₅H₄N₂O₃

Colore e forma: Brownish Powder

Peso molecolare: 140.1

Ref: TM-T10171

5-Hydroxy-2-Pyrazinecarboxylic Acid

CAS: 34604-60-9

Formula: C₅H₄N₂O₃

Peso molecolare: 140.10

Ref: 4Z-P-240003

5-Hydroxypyrazine-2-carboxylic acid

CAS: 34604-60-9

5-Hydroxypyrazine-2-carboxylic acid

Formula: C₅H₄N₂O₃

Purezza: 97%

Colore e forma: dark brown solid

Peso molecolare: 140.10g/mol

Ref: 54-OR40051

5-Hydroxypyrazine-2-carboxylic Acid

CAS: 34604-60-9

Applications A versatile building block for the synthesis of new antituberculous agents. A metabolite of Pyrazinamide (P840600).
References Wieser, M. et al.: Appl. Microbiol. Biotech., 48, 174 (1997); Lacroix, C. et al.: Eur. J. Clin. Pharmacol., 36, 395 (1989);

Formula: C₅H₄N₂O₃

Colore e forma: Light Yellow

Peso molecolare: 140.10

Ref: TR-H952675

5-Hydroxypyrazine-2-carboxylic acid

CAS: 34604-60-9

Formula: C₅H₄N₂O₃

Purezza: 97%

Colore e forma: Solid

Peso molecolare: 140.098

Ref: 10-F037360

5-Hydroxypyrazine-2-carboxylic acid

CAS: 34604-60-9

5-Hydroxypyrazine-2-carboxylic acid is a drug that inhibits the activation of proteins involved in cell signaling pathways. It has been shown to have an inhibitory effect on the activation of protein kinase C, which plays a key role in the proliferation and differentiation of cells. 5-Hydroxypyrazine-2-carboxylic acid also inhibits sorafenib, a drug used for the treatment of cancer. Sorafenib is metabolized in rats by cytochrome P450 (CYP) enzymes, which are found in human liver tissue as well. The metabolism rate of sorafenib can be reduced by coadministration with caffeine or other substances that induce CYP activity. 5-Hydroxypyrazine-2-carboxylic acid is not active against pyrazinoic acid and pyrazine-2 carboxylate, which are metabolites produced by CYP enzymes.

Formula: C₅H₄N₂O₃

Purezza: Min. 98 Area-%

Colore e forma: Brown Powder

Peso molecolare: 140.1 g/mol

Ref: 3D-FH24492

5-Hydroxy-2-Pyrazinecarboxylic Acid-13C3

CAS: 34604-60-9

Formula: C₅H₄N₂O₃

Peso molecolare: 143.07

Ref: 4Z-P-240004