CAS 352518-77-5

c24:1 Ceramide (d17:1/24:1(15Z))

CAS: 352518-77-5

Ceramides are a type of lipid that is important for maintaining the barrier function of skin. Ceramide 24:1 (C24:1) is a putatively pro-inflammatory, anti-proliferative, and immunomodulatory lipid that has been implicated in cancer. C24:1 levels are reduced in the serum of patients with cancer and C24:1 levels are increased in the blood of patients with cancer. Additionally, there is evidence that this lipid plays an important role in metastasis (the spread of cancer to other parts of the body). It has been shown to be associated with poor prognosis and high grade tumours.
Ceramides can be measured as part of a metabolomics analysis to identify metabolic pathways associated with cancer. The validation study will help determine if measurements from this technique can be used as an indicator for cancer risk or diagnosis. The biosynthesis pathway for C24:1 has not yet been determined but there are several strategies being pursued to

Formula: C₄₁H₇₉NO₃

Purezza: Min. 95%

Peso molecolare: 634.07 g/mol

Ref: 3D-CPA51877