CAS 353229-59-1

LY 487379 Hydrochloride

Prodotto controllato

CAS: 353229-59-1

Applications LY 487379 Hydrochloride is a group II mGlu receptors activator with anti-hyperthermic effects. Allosteric potentiators of metabotropic glutamate receptor 2 (mGlu2).
References Wieronska, J. et al.: Neuropharmacol., 62, 322 (2012); Pinkerton, A. et al.: Bioorg. Med. Chem. Lett., 14, 5867 (2004)

Formula: C₂₁H₁₉F₃N₂O₄S·ClH

Colore e forma: Neat

Peso molecolare: 488.908

Ref: TR-L486790

LY 487379-d3 Hydrochloride

Prodotto controllato

CAS: 353229-59-1

Formula: C₂₁D₃H₁₆F₃N₂O₄S·HCl

Colore e forma: Neat

Peso molecolare: 491.926

Ref: TR-L486792

LY 487379-d3 Hydrochloride

CAS: 353229-59-1

LY 487379-d3 Hydrochloride is an experimental drug that belongs to the class of nucleoside analogues. It is an anti-HIV agent that is designed to inhibit deoxycytidine kinase, an enzyme involved in the conversion of deoxythymidine monophosphate (dTMP) to dTTP. LY 487379-d3 Hydrochloride has been shown to be a potent inhibitor of HIV replication in vitro and also inhibits the growth of HIV strains resistant to other nucleoside analogues. Clinical trials are currently underway for this experimental drug.

Formula: C₂₁H₁₇D₃ClF₃N₂O₄S

Purezza: Min. 95%

Peso molecolare: 491.93 g/mol

Ref: 3D-DPA22959

LY487379 hydrochloride

CAS: 353229-59-1

Positive allosteric modulator of mGlu2 receptors

Formula: C₂₁H₂₀ClF₃N₂O₄S

Purezza: 98%

Colore e forma: Solid

Peso molecolare: 488.91

Ref: TM-T22955