CAS 3556-56-7

Ester 4-nitrofenilico di N-[(fenilmetossi)carbonil]-L-tirosina

Descrizione:

Ester 4-nitrofenilico di N-[(fenilmetossi)carbonil]-L-tirosina, con numero CAS 3556-56-7, è un composto chimico che appartiene alla classe dei derivati degli aminoacidi. Presenta una struttura di backbone della tirosina, che è un aminoacido aromatico noto per il suo ruolo nella sintesi proteica e come precursore dei neurotrasmettitori. Il composto è caratterizzato dalla presenza di un gruppo protettivo fenilmetossicarbonile (Pmc), comunemente usato nella sintesi di peptidi per proteggere il gruppo amminico dell'aminoacido. Inoltre, il gruppo estere del 4-nitrofenile contribuisce alla sua reattività, rendendolo utile in varie reazioni chimiche, in particolare nella sintesi di peptidi e altre molecole organiche complesse. Il composto è tipicamente un solido a temperatura ambiente e può mostrare solubilità in solventi organici. Le sue proprietà, come il punto di fusione, la solubilità e la reattività, possono variare in base alle condizioni specifiche e alla purezza del campione. In generale, questo composto è significativo nella sintesi organica e nella biochimica, in particolare nello sviluppo di farmaci e bioconjugati.

Formula: C₂₃H₂₀N₂O₇

InChI: InChI=1S/C23H20N2O7/c26-19-10-6-16(7-11-19)14-21(24-23(28)31-15-17-4-2-1-3-5-17)22(27)32-20-12-8-18(9-13-20)25(29)30/h1-13,21,26H,14-15H2,(H,24,28)/t21-/m0/s1

InChI key: InChIKey=WUHIFOXZYIQZFP-NRFANRHFSA-N

SMILES: [C@H](CC1=CC=C(O)C=C1)(C(OC2=CC=C(N(=O)=O)C=C2)=O)NC(OCC3=CC=CC=C3)=O

Sinonimi:

• 4-nitrophenyl N-[(benzyloxy)carbonyl]tyrosinate
• <span class="text-smallcaps">L</span>-Tyrosine, N-[(phenylmethoxy)carbonyl]-, 4-nitrophenyl ester
• N-(Benzyloxycarbonyl)-<span class="text-smallcaps">L</span>-tyrosine p-nitrophenyl ester
• N-CBZ-L-Tyrosine-p-nitrophenyl ester N-Carbobenzyloxy-L-tyrosine-p-nitrophenyl ester
• N-Carbobenzoxy-<span class="text-smallcaps">L</span>-tyrosine p-nitrophenyl ester
• N-[(Phenylmethoxy)carbonyl]-<span class="text-smallcaps">L</span>-tyrosine 4-nitrophenyl ester
• N-α-Carbobenzoxy-<span class="text-smallcaps">L</span>-tyrosine p-nitrophenyl ester
• NSC 88489
• Tyrosine, N-carboxy-, N-benzyl p-nitrophenyl ester, <span class="text-smallcaps">L</span>-
• Z-Tyr-ONp
• p-Nitrophenyl N-benzyloxycarbonyl-<span class="text-smallcaps">L</span>-tyrosine
• α-N-Benzyloxycarbonyl-<span class="text-smallcaps">L</span>-tyrosine p-nitrophenyl ester
• Tyrosine, N-carboxy-, N-benzyl p-nitrophenyl ester, L-
• N-α-Carbobenzoxy-L-tyrosine p-nitrophenyl ester
• N-[(Phenylmethoxy)carbonyl]-L-tyrosine 4-nitrophenyl ester
• N-(Benzyloxycarbonyl)-L-tyrosine p-nitrophenyl ester

Z-Tyr-Onp

CAS: 3556-56-7

Formula: C₂₃H₂₀N₂O₇

Purezza: 98%

Colore e forma: Solid

Peso molecolare: 436.4141

Ref: IN-DA00BYAK

Z-Tyr-Onp

CAS: 3556-56-7

Z-Tyr-Onp

Purezza: 98%

Peso molecolare: 436.41g/mol

Ref: 54-OR1015469

Z-L-tyrosine 4-nitrophenyl ester

CAS: 3556-56-7

Z-L-tyrosine 4-nitrophenyl ester is a synthetic, inactivated amide that binds to the active site of enzyme, preventing its enzymatic activity. It prevents the formation of clots by cleaving the clotting factors and is used in blood transfusions. Z-L-tyrosine 4-nitrophenyl ester has been shown to inhibit the synthesis of surfactant and is used as an antiseptic. This drug can be prepared by reacting L-tyrosine with nitrophenol (NO2) in the presence of a base such as sodium hydroxide or potassium carbonate, followed by purification on sephadex g-100 columns. The product is then treated with hydrostatic pressure to remove any unreacted starting materials. This drug also has a sedimentation rate of about 1.5 x 10^6 cm/s.

Formula: C₂₃H₂₀N₂O₇

Purezza: Min. 95%

Colore e forma: White/Off-White Solid

Peso molecolare: 436.41 g/mol

Ref: 3D-FT47319

Z-Tyr-ONp

CAS: 3556-56-7

Z-Tyr-ONp is a synthetic, water soluble, non-toxic fibrinogen activator. It has been shown to be effective at low concentrations in the activation of fibrinogen and in the prevention of clotting. Z-Tyr-ONp hydrolyzes fibrinogen to form fibrin clots, which are needed for blood coagulation. This process is mediated by the enzyme alpha-thrombin and is dependent on calcium ions. Z-Tyr-ONp also exhibits surfactant properties that allow it to stabilize micelles that contain lipase enzymes and bile salts, which are required for digestion of dietary fats. The presence of lipase enzymes can enhance the proteolytic activity of Z-Tyr-ONp and increase its ability to dissolve clots.

Formula: C₂₃H₂₀N₂O₇

Purezza: Min. 95%

Peso molecolare: 436.41 g/mol

Ref: 3D-SYN-3016