CAS 355806-00-7

1,1-Dimetiletil (3R,5S,6E)-7-[4-(4-fluorofenil)-6-(1-metiletil)-2-[metil(metilsulfonil)amino]-5-pirimidinil]-3,5-diidrossi-6-eptenoato

Descrizione:

1,1-Dimetiletil (3R,5S,6E)-7-[4-(4-fluorofenil)-6-(1-metiletil)-2-[metil(metilsulfonil)amino]-5-pirimidinil]-3,5-diidrossi-6-eptenoato, con numero CAS 355806-00-7, è un composto organico complesso caratterizzato dalla sua intricatissima struttura molecolare, che include più gruppi funzionali come idrossile, moieties di pirimidina e sulfonamide. Questo composto è notevole per la sua stereochimica, presentando centri chirali specifici che contribuiscono alla sua attività biologica. La presenza di un gruppo fluorofenile suggerisce interazioni potenziali con bersagli biologici, rendendolo di interesse nella chimica medicinale. La sua struttura di backbone di eptenoato indica che potrebbe presentare insaturazione, il che può influenzare la sua reattività e stabilità. La solubilità del composto, il punto di fusione e altre proprietà fisiche dipenderebbero dalle sue interazioni molecolari e dalla presenza di sostituenti. In generale, questa sostanza sarà probabilmente studiata per le sue proprietà farmacologiche, in particolare nel contesto dello sviluppo di farmaci e applicazioni terapeutiche.

Formula: C₂₆H₃₆FN₃O₆S

InChI: InChI=1S/C26H36FN3O6S/c1-16(2)23-21(13-12-19(31)14-20(32)15-22(33)36-26(3,4)5)24(17-8-10-18(27)11-9-17)29-25(28-23)30(6)37(7,34)35/h8-13,16,19-20,31-32H,14-15H2,1-7H3/b13-12+/t19-,20-/m1/s1

InChI key: InChIKey=IJHZGLLGELSZAF-OKLSWEBGSA-N

SMILES: C(=C/[C@H](C[C@H](CC(OC(C)(C)C)=O)O)O)\C=1C(=NC(N(S(C)(=O)=O)C)=NC1C(C)C)C2=CC=C(F)C=C2

Sinonimi:

• (+)-(3r, 5s)-7-[4-(4-Fluorophenyl)-6-Isopropyl-2-(N-Methyl-N-Methanesulfonylamino)Pyrimidin-5-Yl]-(3, 5)-Dihydroxy-6(E)-Heptenoate
• (3R,5S,6E)-7-[4-(4-Fluorophenyl)-6-isopropyl-2-[(methanesulfonyl)methylamino]pyrimidin-5-yl]-3,5-dihydroxyhept-6-enoic acid tert-butyl ester
• (3R,5S,6E)-7-[4-(4-fluorophenyl)-6-isopropyl-2-(N-methyl-N-methylsulfonyl amino)pyrinidine-5-yl]-3,5-dihydrosy-6-heptane acid,dimethylethyl ester
• 1,1-Dimethylethyl (3R,5S,6E)-7-[4-(4-fluorophenyl)-6-(1-methylethyl)-2-[methyl(methylsulfonyl)amino]-5-pyrimidinyl]-3,5-dihydroxy-6-heptenoate
• 6-Heptenoic acid, 7-[4-(4-fluorophenyl)-6-(1-methylethyl)-2-[methyl(methylsulfonyl)amino]-5-pyrimidinyl]-3,5-dihydroxy-, 1,1-dimethylethyl ester, (3R,5S,6E)-
• Rosuvastatin calcium intermediate R-3
• Rosuvastatin tert-Butyl Ester
• tert-Butyl rosuvastatin
• tert-Butyl(6E)-7-[4-(4-fluorophenyl)-6-isopropyl-2-[methyl(methylsulfonyl)amino]pyrimidin-5-yl]-(3R,5S)-3,5-dihydroxyhept-6-enoate
• tert-butyl (3R,5S,6E)-7-{4-(4-fluorophenyl)-6-(1-methylethyl)-2-[methyl(methylsulfonyl)amino]pyrimidin-5-yl}-3,5-dihydroxyhept-6-enoate

6-Heptenoic acid,7-[4-(4-fluorophenyl)-6-(1-methylethyl)-2-[methyl(methylsulfonyl)amino]-5-pyrimidinyl]-3,5-dihydroxy-, 1,1-dimethylethyl ester, (3R,5S,6E)-

CAS: 355806-00-7

Formula: C₂₆H₃₆FN₃O₆S

Purezza: 98%

Colore e forma: Solid

Peso molecolare: 537.6439

Ref: IN-DA00I726

Rosuvastatin tert-butyl ester

CAS: 355806-00-7

Rosuvastatin tert-butyl ester

Purezza: 98%

Peso molecolare: 537.64g/mol

Ref: 54-PC111420

Rosuvastatin tert-Butyl Ester

CAS: 355806-00-7

Formula: C₂₆H₃₆FN₃O₆S

Colore e forma: White To Off-White Solid

Peso molecolare: 537.65

Ref: 4Z-R-099

Rosuvastatin Impurity 37

CAS: 355806-00-7

Formula: C₂₆H₃₇N₃O₆S

Colore e forma: White To Off-White Solid

Peso molecolare: 519.66

Ref: 4Z-R-0995

Rosuvastatin tert-Butyl Ester

Prodotto controllato

CAS: 355806-00-7

Stability Hygroscopic
Applications Rosuvastatin tert-Butyl Ester, is a metabolite of Rosuvastatin (R700500) a selective, competitive HMG-CoA reductase inhibitor.
References Watanabe, M., et al.: Bioorg. Med. Chem., 5, 437 (1997), Lee, E., et al.: Clin. Pharmacol. Ther., 78, 330 (2005), Ferdinand, K.C., et al.: Am. J. Cardiol., 97, 229 (2006),

Formula: C₂₆H₃₆FN₃O₆S

Colore e forma: Neat

Peso molecolare: 537.64

Ref: TR-R700540

(3R,5S,6E)-7-[4-(4-FLUOROPHENYL)-6-ISOPROPYL-2-[(METHANESULFONYL) METHYLAMINO]PYRIMIDIN-5-YL]-3,5-DIHYDROXYHEPT-6-ENOIC ACID TERT-BUTYL ESTER

CAS: 355806-00-7

Purezza: 98%

Peso molecolare: 537.6500244

Ref: 10-F835716

Rosuvastatin Acid t-Butyl Ester

CAS: 355806-00-7

Formula: C₂₆H₃₆FN₃O₆S

Peso molecolare: 537.65

Ref: ST-EA-CP-R1080

Tert-Butyl Rosuvastatin

CAS: 355806-00-7

Tert-Butyl Rosuvastatin is a synthetic statin. It has a high melting point, which can be used to separate the optical isomers. The tert-butyl group of the rosuvastatin molecule makes it soluble in organic solvents such as tetrahydrofuran, while the ester side chain makes it hydrolysis resistant. Tert-Butyl Rosuvastatin was found to be free of impurities and had a purity of at least 99% by liquid chromatography analysis. Analysis by mass spectrometry confirmed that no other alkali metal ions were present at greater than 0.1%.

Formula: C₂₆H₃₆FN₃O₆S

Purezza: Min. 95%

Peso molecolare: 537.65 g/mol

Ref: 3D-FT35382