CAS 356068-93-4

5-((Z)-(5-Fluoro-2-ossoindolin-3-ilidene)metil)-2,4-dimetil-1H-pirrolo-3-carbossilico acido

Descrizione:

5-((Z)-(5-Fluoro-2-ossoindolin-3-ilidene)metil)-2,4-dimetil-1H-pirrolo-3-carbossilico acido, con numero CAS 356068-93-4, è un composto organico sintetico caratterizzato dalla sua struttura complessa, che include un anello di pirrolo, un gruppo funzionale acido carbossilico e una moiety di indolinone. La presenza dell'atomo di fluoro suggerisce un potenziale per un'attività biologica migliorata o proprietà fisico-chimiche alterate. Questo composto può presentare proprietà interessanti come solubilità in solventi organici, stabilità moderata in condizioni standard e reattività potenziale a causa del gruppo acido carbossilico. La sua struttura unica può conferire attività biologiche specifiche, rendendolo un candidato per la ricerca farmaceutica, in particolare nello sviluppo di nuovi agenti terapeutici. La sintesi e la caratterizzazione del composto comporterebbero normalmente tecniche come la spettroscopia NMR, la spettrometria di massa e possibilmente la cristallografia a raggi X per confermare la sua struttura molecolare e purezza. In generale, questo composto rappresenta una classe di composti eterociclici di grande interesse nella chimica medicinale e nello sviluppo di farmaci.

Formula: C₁₆H₁₃FN₂O₃

InChI: InChI=1/C16H13FN2O3/c1-7-13(18-8(2)14(7)16(21)22)6-11-10-5-9(17)3-4-12(10)19-15(11)20/h3-6,18H,1-2H3,(H,19,20)(H,21,22)/b11-6-

SMILES: Cc1c(/C=C\2/c3cc(ccc3N=C2O)F)[nH]c(C)c1C(=O)O

Sinonimi:

• 1H-pyrrole-3-carboxylic acid, 5-[(Z)-(5-fluoro-1,2-dihydro-2-oxo-3H-indol-3-ylidene)methyl]-2,4-dimethyl-
• 5-[(Z)-(5-Fluoro-2-oxo-1,2-dihydro-3H-indol-3-ylidene)methyl]-2,4-dimethyl-1H-pyrrole-3-carboxylic acid
• (Z)-5-[(5-Fluoro-2-oxoindolin-3-ylidene)methyl]-2,4-dimethylpyrrole-3-carboxylic Acid
• 5-((Z)-(5-Fluoro-2-oxoindolin-3-ylidene)methyl)-2,4-dimethyl...
• (3Z)-3-[(3,5-Dimethyl-4-carboxy-1H-pyrrol-2-yl)methylidene]-5-fluoro-1,3-dihydro-2H-indol-2-on
• Des-N-(2-Diethylaminoethyl)amide Sunitinib Acid
• (Z)-5-((5-fluoro-2-oxoindolin-3-ylidene)Methyl)-2,4-diMethyl-1H-pyrrole-3-carboxylic acid
• (3Z)-3-[(3,5-DiMethyl-4-carboxy-1H-pyrrol-2-yl)Methylidene]-5-fluoro-1,3-dihydro-2H-indol-2-one
• 5-((Z)-(5-Fluoro-2-oxoindolin-3-ylidene)methyl)-2,4-dimethyl-1H-pyrrole-3-carboxylic acid

(Z)-5-((5-Fluoro-2-oxoindolin-3-ylidene)methyl)-2,4-dimethyl-1H-pyrrole-3-carboxylic acid

CAS: 356068-93-4

Purezza: 95.0%

Colore e forma: Solid

Peso molecolare: 300.28900146484375

Ref: 10-F238886

5-((Z)-(5-Fluoro-2-oxoindolin-3-ylidene)methyl)-2,4-dimethyl-1H-pyrrole-3-carboxylic acid

CAS: 356068-93-4

Formula: C₁₆H₁₃FN₂O₃

Purezza: 98%

Colore e forma: Solid

Peso molecolare: 300.2844

Ref: IN-DA0037KR

5-((Z)-(5-Fluoro-2-oxoindolin-3-ylidene)methyl)-2,4-dimethyl-1H-pyrrole-3-carboxylic acid

CAS: 356068-93-4

Ref: 7W-GX6190

(Z)-5-((5-fluoro-2-oxoindolin-3-ylidene)methyl)-2,4-dimethyl-1H-pyrrole-3-carboxylic acid

CAS: 356068-93-4

(Z)-5-((5-fluoro-2-oxoindolin-3-ylidene)methyl)-2,4-dimethyl-1H-pyrrole-3-carboxylic acid

Purezza: 98%

Peso molecolare: 300.289g/mol

Ref: 54-PC99839

5-[(Z)-(5-Fluoro-2-oxo-indolin-3-ylidene)methyl]-2,4-dimethyl-1H-pyrrole-3-carboxylic Acid

Prodotto controllato

CAS: 356068-93-4

Formula: C₁₆H₁₃FN₂O₃

Colore e forma: Neat

Peso molecolare: 300.28

Ref: 86-MM3568.04

Sunitinib Impurity 13

CAS: 356068-93-4

Formula: C₁₆H₁₃FN₂O₃

Peso molecolare: 300.3

Ref: ST-EA-CP-S42036

5-((Z)-(5-fluoro-2-oxoindolin-3-ylidene)methyl)-2,4-dimethyl-1H-pyrrole-3-carboxylic acid

CAS: 356068-93-4

5-((Z)-(5-fluoro-2-oxoindolin-3-ylidene)methyl)-2,4-dimethyl is an inhibitor of protein kinase. It inhibits the activity of protein kinase C (PKC) and also has immunosuppressive properties. 5-(2,4-Dimethylphenyl)-5-[(5-fluoroindolinylidene)methyl]pyrrole is a white to off white crystalline powder that belongs to the class of pyrroles. It has been shown to be a vasotropic agent by binding to the alpha 1 beta 1 integrin receptor on vascular smooth muscle cells. This drug binds to aminophospholipids in plasma and can cause osteopathic lesions when injected into bone tissue. 5-(2,4-Dimethylphenyl)-5-[(5-fluoroindolinylidene)methyl]pyrrole has been shown to have antiinflammatory effects

Formula: C₁₆H₁₃FN₂O₃

Purezza: Min. 95%

Peso molecolare: 300.28 g/mol

Ref: 3D-FF106180

Des-N-(2-Diethylaminoethyl)amide Sunitinib Acid

Prodotto controllato

CAS: 356068-93-4

Applications Des-N-(2-Diethylaminoethyl)amide Sunitinib Acid is an impurity of Sunitinib (S819995), a multi-kinase inhibitor targeting several receptor tyrosine kinases (RTK). Antineoplastic.
References Sun, L., et al.: J. Med. Chem., 46, 1116 (2003); Mendel, D.B., et al.: Clin. Cancer Res., 9, 327 (2003); Sistla, A., et al.: Drug Dev. Ind. Pharm., 30, 19 (2004); Sakamoto, K.M., et al.: Curr. Opin. Invest. Drugs, 5. 1329 (2004)

Formula: C₁₆H₁₃FN₂O₃

Colore e forma: Neat

Peso molecolare: 300.28

Ref: TR-D367070

(Z)-5-((5-Fluoro-2-oxoindolin-3-ylidene)methyl)-2,4-dimethyl-1H-pyrrole-3-carboxylic acid

CAS: 356068-93-4

(Z)-5-((5-Fluoro-2-oxoindolin-3-ylidene)methyl)-2,4-dimethyl-1H-pyrrole-3-carboxylic acid is a useful organic compound for research related to life sciences. The catalog number is T65586 and the CAS number is 356068-93-4.

Formula: C₁₆H₁₃FN₂O₃

Colore e forma: Solid

Peso molecolare: 300.289

Ref: TM-T65586