CAS 356068-99-0

Sunitinib N-Oxide ((Z)-N,N-diethyl-2-(5-((5-fluoro-2-oxoindolin-3-ylidene)methyl)-2,4-dimethyl-1H-pyrrole-3-carboxamido)ethan-1-amine oxide)

CAS: 356068-99-0

Lactams, nesoi

Formula: C₂₂H₂₇FN₄O₃

Colore e forma: Yellow Orange Solid

Peso molecolare: 414.20672

Ref: 45-1A05050

Sunitinib N-Oxide

CAS: 356068-99-0

Formula: C₂₂H₂₇FN₄O₃

Colore e forma: Orange Solid

Peso molecolare: 414.48

Ref: 4Z-S-415

Sunitinib N-Oxide

CAS: 356068-99-0

Colore e forma: Neat

Ref: 86-MM3568.05

Sunitinib N-Oxide

CAS: 356068-99-0

Formula: C₂₂H₂₇FN₄O₃

Peso molecolare: 414.48

Ref: ST-EA-CP-S42009

Sunitinib N-Oxide

CAS: 356068-99-0

Stability Hygroscopic
Applications Sunitinib N-Oxide, is a derivative of Sunitinib (S820000), a multi-kinase inhibitor targeting several receptor tyrosine kinases (RTK), used for the treatment of renal cell carcinoma (RCC) and imatinib-resistant gastrointestinal stromal tumor. It is a COVID19-related research product.
References Sun, L., et al.: J. Med. Chem., 46, 1116 (2003), Mendel, D.B., et al.: Clin. Cancer Res., 9, 327 (2003), Sistla, A., et al.: Drug Dev. Ind. Pharm., 30, 19 (2004), Sakamoto, K.M., et al.: Curr. Opin. Invest. Drugs, 5. 1329 (2004),

Formula: C₂₂H₂₇FN₄O₃

Colore e forma: Neat

Peso molecolare: 414.47

Ref: TR-S820005

Sunitinib N-Oxide-d10

Prodotto controllato

CAS: 356068-99-0

Formula: C₂₂D₁₀H₁₇FN₄O₃

Colore e forma: Neat

Peso molecolare: 424.535

Ref: TR-S820007

Sunitinib N-oxide

CAS: 356068-99-0

Sunitinib N-oxide is the active form of sunitinib, a drug that is used to treat cancer. Sunitinib N-oxide is a photolabile n-oxide and can be converted to sunitinib by exposure to light. This conversion process can be used as an analytical technique for determining the concentration of the drug in blood or tissue samples. Sunitinib N-oxide has been shown to reduce tumor growth in mouse models and also inhibits angiogenesis and tumor metastasis. The drug has also been shown to have anti-inflammatory effects, which may be due to its inhibition of prostaglandin synthesis.

Formula: C₂₂H₂₇FN₄O₃

Purezza: Min. 95%

Colore e forma: White Powder

Peso molecolare: 414.47 g/mol

Ref: 3D-FS146111