CAS 3562-84-3

benzbromarone

Descrizione:

benzbromarone è un composto organico sintetico utilizzato principalmente come agente uricosurico nel trattamento della gotta e dell'iperuricemia. Funziona inibendo il riassorbimento dell'acido urico nei reni, promuovendo così la sua escrezione. Il composto è caratterizzato dalla sua formula molecolare, che include un gruppo bromobenzene, contribuendo alle sue proprietà farmacologiche. benzbromarone è tipicamente somministrato per via orale ed è noto per la sua relativamente alta biodisponibilità. Presenta una solubilità moderata ad alta nei solventi organici, ma è meno solubile in acqua. Il composto ha una lunga emivita, consentendo una somministrazione una volta al giorno in contesti clinici. Gli effetti collaterali possono includere disturbi gastrointestinali e, in rari casi, tossicità epatica, richiedendo il monitoraggio della funzione epatica durante il trattamento. Il meccanismo d'azione e l'efficacia di benzbromarone lo rendono un'opzione preziosa nella gestione delle condizioni associate a livelli elevati di acido urico, sebbene il suo uso possa essere limitato da potenziali effetti avversi e controindicazioni in alcune popolazioni di pazienti.

Formula: C₁₇H₁₂Br₂O₃

InChI: InChI=1/C17H12Br2O3/c1-2-13-15(10-5-3-4-6-14(10)22-13)16(20)9-7-11(18)17(21)12(19)8-9/h3-8,21H,2H2,1H3

InChI key: InChIKey=WHQCHUCQKNIQEC-UHFFFAOYSA-N

SMILES: C(=O)(C=1C=2C(OC1CC)=CC=CC2)C3=CC(Br)=C(O)C(Br)=C3

Sinonimi:

• (3,5-Dibromo-4-hydroxyphenyl)(2-ethyl-3-benzofuranyl)methanone
• (3,5-Dibromo-4-hydroxyphenyl)(2-ethylbenzofuran-3-yl)methanone
• (3,5-Dibromo-4-hydroxyphenyl)-(2-ethyl-1-benzofuran-3-yl)methanone
• 2-Ethyl-3-(3,5-dibromo-4-hydroxybenzoyl)benzofuran
• 3,5-Dibromo-4-Hydroxyphenyl-2-Ethylbenzo[B]Furan-3-Yl Ketone
• 3,5-Dibromo-4-hydroxyphenyl 2-ethyl-3-benzofuranyl ketone
• Azubromaron
• Benzbromaron
• Besuric
• Desuric
• Ketone, 3,5-dibromo-4-hydroxyphenyl 2-ethyl-3-benzofuranyl
• L 2214
• L 2214-Labaz
• Max-Uric
• Methanone, (3,5-dibromo-4-hydroxyphenyl)(2-ethyl-3-benzofuranyl)-
• Minuric
• Mj 10061
• NSC 85433
• Narcaricin
• Normurat
• Uricovac
• Urinorm
• Benzbromarone
• mj10061
• BENZBROMARONE, MM(CRM STANDARD)
• l2214-labaz
• exurate
• l2214
• (3,5-dibromo-4-hydroxyphenyl)(2-ethyl-3-benzofuranyl)-methanon
• 3-(3,5-dibromo-4-hydroxybenzoyl)-2-ethyl-benzofura
• (3,5-Dibromo-4-hydroxyphenyl)(2-ethylbenzofuran-3-yl)ketone
• LABOTEST-BB LT00134669
• 3,5-dibromo-4-hydroxyphenyl2-ethyl-3-benzofuranylketone
• 3-[3,5-DIBROMO-4-HYDROXYBENZOYL]-2-ETHYLBENZOFURAN
• ketone,3,5-dibromo-4-hydroxyphenyl2-ethyl-3-benzofuranyl

BENZBROMARONE CRS

CAS: 3562-84-3

BENZBROMARONE CRS

Formula: C₁₇H₁₂Br₂O₃

Colore e forma: Added Modified

Peso molecolare: 424.0834

Ref: 41-Y0000775

Benzbromarone

CAS: 3562-84-3

Formula: C₁₇H₁₂Br₂O₃

Purezza: 95%

Colore e forma: Solid

Peso molecolare: 424.0834

Ref: IN-DA003AX3

Benzbromarone

CAS: 3562-84-3

Benzbromarone (Desuric) is a CYP2C9 inhibitor with Ki value of 19.3 nM.

Formula: C₁₇H₁₂Br₂O₃

Purezza: 99.37% - 99.73%

Colore e forma: Solid

Peso molecolare: 424.08

Ref: TM-T1274

Benzbromarone

CAS: 3562-84-3

Benzbromarone

Purezza: ≥98%

Peso molecolare: 424.08g/mol

Ref: 54-BUP17025

Benzbromarone

CAS: 3562-84-3

Benzbromarone

Purezza: 98%

Peso molecolare: 424.08g/mol

Ref: 54-OR1012321

Benzbromarone-d5

CAS: 3562-84-3

Formula: C₁₇H₇D₅Br₂O₃

Peso molecolare: 429.12

Ref: 4Z-B-079013

Benzbromarone

CAS: 3562-84-3

Formula: C₁₇H₁₂Br₂O₃

Peso molecolare: 424.09

Ref: 4Z-B-079003

Benzbromarone

CAS: 3562-84-3

Formula: C₁₇H₁₂Br₂O₃

Purezza: (GC) ≥ 98.0%

Colore e forma: White to pale yellow powder or crystals

Peso molecolare: 424.08

Ref: 7W-GP8819

Benzbromarone

CAS: 3562-84-3

Formula: C₁₇H₁₂Br₂O₃

Purezza: >98.0%(GC)(T)

Colore e forma: White to Light yellow powder to crystal

Peso molecolare: 424.09

Ref: 3B-B4099

Benzbromarone

Prodotto controllato

CAS: 3562-84-3

Formula: C₁₇H₁₂Br₂O₃

Colore e forma: Neat

Peso molecolare: 424.08

Ref: 86-MM0456.00

Benzbromarone

Prodotto controllato

CAS: 3562-84-3

Formula: C₁₇H₁₂Br₂O₃

Colore e forma: Neat

Peso molecolare: 424.08

Ref: 04-C10534000

Benzbromarone-d4

CAS: 3562-84-3

Formula: C₁₇H₈D₄Br₂O₃

Peso molecolare: 428.11

Ref: 4Z-B-079011

Benzbromarone

Prodotto controllato

CAS: 3562-84-3

Applications Benzbromarone is a uricosuric agent used in the treatment of gout and hyperuricemia. Studies show that use of Benzbromarone results in less complications than other uricosuric agent such as Allopurinol.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Heel, R.C. et al.: Drugs, 14, 349 (1977); Perez-Ruiz, F. et al.: Ann. Rheum. Dis., 57, 545 (1998);

Formula: C₁₇H₁₂Br₂O₃

Colore e forma: Off-White

Peso molecolare: 424.08

Ref: TR-B185200

Benzbromarone-D5

Prodotto controllato

CAS: 3562-84-3

Formula: C₁₇D₅H₇Br₂O₃

Colore e forma: Neat

Peso molecolare: 429.114

Ref: TR-B185202

(3,5-Dibromo-4-hydroxyphenyl)(2-ethyl-3-benzofuranyl)methanone

CAS: 3562-84-3

3,5-Dibromo-4-hydroxyphenyl-(2-ethyl-3-benzofuranyl)methanone (DBF) is a synthetic molecule that has been shown to be effective against obesity by reducing the size of fat cells. DBF was originally developed as an anti-inflammatory drug for psoriasis and arthritis. It has also been shown to have antioxidant and anti-cancer properties. DBF binds to toll-like receptor 4 (TLR4), which is involved in the inflammatory response, and inhibits its activation. This inhibition leads to a decrease in proinflammatory cytokines such as tumor necrosis factor alpha (TNFα). DBF also reduces the mitochondrial membrane potential, which may be due to its ability to inhibit ATP production by mitochondria and/or block mitochondrial protein synthesis.

Formula: C₁₇H₁₂Br₂O₃

Purezza: Min. 95%

Colore e forma: Powder

Peso molecolare: 424.08 g/mol

Ref: 3D-FD18180

BENZBROMARONE

CAS: 3562-84-3

Purezza: 95%

Peso molecolare: 424.0880127

Ref: 10-F811899

Benzbromarone

CAS: 3562-84-3

Formula: C₁₇H₁₂Br₂O₃

Peso molecolare: 424.08

Ref: ST-EA-CP-B46000

Benzbromarone

CAS: 3562-84-3

Colore e forma: Neat

Ref: 61-FOR0456.00

Benzbromarone 1.0 mg/ml in Methanol

CAS: 3562-84-3

Colore e forma: Single Solution

Ref: 61-AMP0456.00-01