CAS 364-98-7

Diazossido

Descrizione:

Diazossido è un composto farmaceutico utilizzato principalmente come agente antipertensivo e nella gestione dell'ipoglicemia. È classificato come un derivato delle tiazidi e funziona rilassando il muscolo liscio vascolare, portando a vasodilatazione e a una successiva diminuzione della pressione sanguigna. La struttura chimica di Diazossido include un anello di diazina, che contribuisce alle sue proprietà farmacologiche. Viene generalmente somministrato per via orale e ha una emivita relativamente lunga, consentendo effetti sostenuti. Diazossido è anche noto per la sua capacità di inibire la secrezione di insulina dal pancreas, rendendolo utile in specifici scenari clinici, come nei pazienti con insulinoma o altre condizioni associate a una produzione eccessiva di insulina. Il composto è generalmente ben tollerato, ma può causare effetti collaterali come ritenzione di liquidi, tachicardia e iperglicemia. A causa dei suoi potenti effetti, Diazossido è solitamente prescritto sotto attenta supervisione medica, in particolare nei pazienti con problemi cardiovascolari. Il suo numero CAS, 364-98-7, è utilizzato per l'identificazione in database chimici e contesti normativi.

Formula: C₈H₇ClN₂O₂S

InChI: InChI=1/C8H7ClN2O2S/c1-5-10-7-3-2-6(9)4-8(7)14(12,13)11-5/h2-4H,1H3,(H,10,11,12,13)

InChI key: InChIKey=GDLBFKVLRPITMI-UHFFFAOYSA-N

SMILES: O=S1(=O)C=2C(NC(C)=N1)=CC=C(Cl)C2

Sinonimi:

• 2H-1,2,4-Benzothiadiazine, 7-chloro-3-methyl-, 1,1-dioxide
• 3-Methyl-7-chloro-1,2,4-benzothiadiazine 1,1-dioxide
• 4H-1,2,4-Benzothiadiazine, 7-chloro-3-methyl-, 1,1-dioxide
• 7-Chloro-3-Methyl-1Lambda~4~,2,4-Benzothiadiazin-1-Ol 1-Oxide
• 7-Chloro-3-methyl-2H-benzo[1,2,4]thiadiazine 1,1-dioxide
• 7-Chloro-3-methyl-4H-benzo[1,2,4]thiadiazine 1,1-dioxide
• 7-chloro-3-methyl-2H-1,2,4-benzothiadiazine 1,1-dioxide
• 7-chloro-3-methyl-4H-1,2,4-benzothiadiazine 1,1-dioxide
• Diazoxid
• Diazoxido
• Dizoxide
• Eudemine injection
• Hyperstat
• Hypertonalum
• Mutabase
• Nsc 64198
• Nsc 76130
• Proglicem
• Proglycem
• Sch 6783
• Srg 95213
• Diazoxide
• DIAZOXIDE 364-98-7 kf-wang(at)kf-chem.com
• DIAZOXIDE ACTIVATOR OF ATP-DEPE
• 7-chloro-3-methyl-4H-benzo[e][1,2,4]thiadiazine 1,1-dioxide
• Diazoxide Benzothiadiazinone Analog
• 7-cloro-3-metil-2h-1,2,4-benzotiodiazina-1,1-diossido
• Diazoxide (200 mg)
• Desipramine Impurity 7
• 7-Chloro-3-methyl-2H-1,2,4-benzothiadiazine1
• Diazoxide-13CD3
• Diazoxide API
• Diazoxide,7-Chloro-3-methyl-2H-1,2,4-benzothiadiazine 1,1-dioxide
• Diazoxide impurity-4 (7-chloro-3-methyl-2H-1,2,4-benzothiadiazine 1,1-dioxide)
• Diazoxide CRS
• DIAZOXIDE,USP
• 7-chloro-3-methyl-4H-1λ,2,4-benzothiadiazine-1,1-dione
• Diazoxided
• DIAZOXIDE USP/EP/BP
• srg95213
• Eudemine
• Diazoxide (1186000)
• 7-chloro-3-methyl-4h-1λ6,2,4-benzothiadiazine 1,1-dioxide

Diazoxide

CAS: 364-98-7

Colore e forma: Neat

Ref: 61-FOR3038.00

DIAZOXIDE CRS

CAS: 364-98-7

DIAZOXIDE CRS

Formula: C₈H₇ClN₂O₂S

Colore e forma: Crystalline Powder. White. Whitish. Powder.

Peso molecolare: 230.6714

Ref: 41-D0950000

Diazoxide

CAS: 364-98-7

Nucleic acids and their salts, whether or not chemically defined; other heterocyclic compounds, nesoi

Formula: C₈H₇ClN₂O₂S

Colore e forma: White Off-White Crystalline Powder

Peso molecolare: 229.99168

Ref: 45-1186000

DIAZOXIDE

CAS: 364-98-7

Formula: C₈H₇ClN₂O₂S

Purezza: 98%

Colore e forma: Solid

Peso molecolare: 230.6714

Ref: IN-DA0039DY

Diazoxide

CAS: 364-98-7

Diazoxide (Proglycem) is a benzothiadiazine derivative that is a peripheral vasodilator used for hypertensive emergencies.

Formula: C₈H₇ClN₂O₂S

Purezza: 99% - 99.83%

Colore e forma: Solid

Peso molecolare: 230.67

Ref: TM-T0126

Diazoxide

CAS: 364-98-7

Formula: C₈H₇ClN₂O₂S

Purezza: ≥ 98.0%

Colore e forma: White to off-white powder

Peso molecolare: 230.67

Ref: 7W-GP7721

Diazoxide

CAS: 364-98-7

Diazoxide

Purezza: ≥98%

Peso molecolare: 230.67g/mol

Ref: 54-BUP16547

Diazoxide

CAS: 364-98-7

Diazoxide

Purezza: 98%

Peso molecolare: 230.67g/mol

Ref: 54-OR1012812

Diazoxide

CAS: 364-98-7

Formula: C₈H₇ClN₂O₂S

Peso molecolare: 230.67

Ref: 4Z-D-431

Diazoxide

CAS: 364-98-7

Formula: C₈H₇ClN₂O₂S

Purezza: >98.0%(T)(HPLC)

Colore e forma: White to Light yellow powder to crystal

Peso molecolare: 230.67

Ref: 3B-D5402

Diazoxide

CAS: 364-98-7

Formula: C₈H₇ClN₂O₂S

Colore e forma: Neat

Peso molecolare: 230.67

Ref: 86-MM3038.00

Diazoxide-d6

CAS: 364-98-7

Formula: C₈HD₆ClN₂O₂S

Peso molecolare: 236.70

Ref: 4Z-D-435

Diazoxide

Prodotto controllato

CAS: 364-98-7

Applications Diazoxide reduces status epilepticus neuron damage in diabetes. A potassium channel opener
References Baba, A., et al.: J. Neurosci., 23, 7737 (2003), Bancila, V., et al.: J. Neurochem., 90, 1243 (2004), Bancila, V., et al.: J. Biol. Chem., 280, 8793 (2005),

Formula: C₈H₇ClN₂O₂S

Colore e forma: Neat

Peso molecolare: 230.67

Ref: TR-D417305

Diazoxide

CAS: 364-98-7

Formula: C₈H₇ClN₂O₂S

Purezza: 95%

Colore e forma: Solid

Peso molecolare: 230.67

Ref: 10-F047209

Diazoxide

CAS: 364-98-7

Formula: C₈H₇ClN₂O₂S

Peso molecolare: 230.67

Ref: ST-EA-CP-D213000

Diazoxide

CAS: 364-98-7

Diazoxide is a drug that belongs to the class of pharmacological agents. It is used as a primary pulmonary hypertension treatment. Diazoxide is an uncoupler of oxidative phosphorylation and it also acts on mitochondria in the cells. Diazoxide has been shown to decrease insulin levels in maternal blood, which may be due to its ability to inhibit insulin release from pancreatic beta cells. This drug also has antioxidant properties, which may be due to its ability to reduce lipid peroxidation and protein oxidation. Diazoxide has been shown to have beneficial effects for bowel diseases such as ulcerative colitis and Crohn's disease, due to its antioxidant properties and its ability to inhibit oxidative injury in the gut wall. Diazoxide inhibits channels that are involved in neuronal death, which is associated with stroke-induced brain damage.

Formula: C₈H₇ClN₂O₂S

Purezza: Min. 97 Area-%

Colore e forma: White To Off-White To Grey Solid

Peso molecolare: 230.67 g/mol

Ref: 3D-FD21519