CAS 365441-71-0

Poli(ossi-1,2-etanedile), α-[3-[(2,5-diosso-1-pirrolidinil)ossi]-3-ossopropil]-ω-[2-[[5-[(3aS,4S,6aR)-esaidro-2-osso-1H-tieno[3,4-d]imidazol-4-il]-1-ossopentil]amino]etossi]-

Descrizione:

Poli(ossi-1,2-etanedile), α-[3-[(2,5-diosso-1-pirrolidinil)ossi]-3-ossopropil]-ω-[2-[[5-[(3aS,4S,6aR)-esaidro-2-osso-1H-tieno[3,4-d]imidazol-4-il]-1-ossopentil]amino]etossi]- è un polimero sintetico complesso caratterizzato dalla sua struttura a polietere e dai gruppi funzionali che ne migliorano la solubilità e la reattività. Questa sostanza generalmente presenta proprietà come la biocompatibilità, rendendola adatta per applicazioni farmaceutiche, in particolare nei sistemi di somministrazione dei farmaci. La presenza di vari gruppi funzionali, inclusi i moieties pirrolidinici e tieno[3,4-d]imidazolo, suggerisce potenziali interazioni con sistemi biologici, che possono facilitare la somministrazione mirata o migliorare l'efficacia degli agenti terapeutici. Inoltre, la struttura del polimero può consentire modifiche che possono adattare le sue proprietà per applicazioni specifiche, come nello sviluppo di idrogeli o altri materiali avanzati. In generale, questo composto rappresenta una piattaforma versatile nella chimica medicinale e nella scienza dei materiali, con implicazioni per migliorare la solubilità e la biodisponibilità dei farmaci.

Formula: (C₂H₄O)nC₁₉H₂₈N₄O₇S

InChI: InChI=1S/C21H32N4O8S/c26-16(4-2-1-3-15-20-14(13-34-15)23-21(30)24-20)22-8-10-32-12-11-31-9-7-19(29)33-25-17(27)5-6-18(25)28/h14-15,20H,1-13H2,(H,22,26)(H2,23,24,30)

InChI key: InChIKey=UCJSJBIJPAZUGU-UHFFFAOYSA-N

SMILES: C(CCCC(NCCOCCOCCC(ON1C(=O)CCC1=O)=O)=O)C2C3C(CS2)NC(=O)N3

Sinonimi:

• (+)-Biotin-PEG12-CH2CH2COONHS Ester
• EZ-Link NHS-PEG12-Biotin
• alpha-[3-[(2,5-Dioxo-1-pyrrolidinyl)oxy]-3-oxopropyl]-omega-[2-[[5-[(3aS,4S,6aR)-hexahydro-2-oxo-1H-thieno[3,4-d]imidazol-4-yl]-1-oxopentyl]amino]ethoxy]-poly(oxy-1,2-ethanediyl)
• (+)-BIOTIN-PEG24-NHS ESTER
• Poly(oxy-1,2-ethanediyl), α-[3-[(2,5-dioxo-1-pyrrolidinyl)oxy]-3-oxopropyl]-ω-[2-[[5-[(3aS,4S,6aR)-hexahydro-2-oxo-1H-thieno[3,4-d]imidazol-4-yl]-1-oxopentyl]amino]ethoxy]-
• Biotin-PEG24-SPA
• NHS-PEO12-Biotin
• -NHS Ester
• Biotin-PEG12-NHS ester
• (+)-Biotin-PEG??-NHS Ester
• Biotin-PEG12-SPA
• Biotin-dPEG(24)-NHS
• Biotin-PEGn-NHS ester
• NHS-PEG12-Biotin
• NHS-dPEG???-biotin
• (+)-BIOTIN-PEG24-NHS ESTER;(+)-BIOTIN-PEG24-NHS ESTER
• 24
• (+)-Biotin-PEG

Biotin-PEG12-NHS ester

CAS: 365441-71-0

Formula: C₁₉H₂₈N₄O₇S

Purezza: 95%

Colore e forma: Solid

Peso molecolare: 456.5132

Ref: IN-DA00CILH

Biotin-PEG12-NHS

CAS: 365441-71-0

Biotin-PEG12-NHS is a PEG compound with two different functional groups (also known as heterobifunctional). Unlike homobifunctional PEG compounds (same functional group on both ends), this type of compounds are more versatile as have two different anchor points. Biotin-PEG12-NHS is used as a linker and spacer to add a PEG moiety, via pegylation (a bioconjugation technique) to proteins, peptides, oligonucleotides, small molecules and nanoparticles.

Formula: C₄₁H₇₂N₄O₁₈S

Purezza: Min. 95%

Colore e forma: White To Off-White Solid

Peso molecolare: 941.09 g/mol

Ref: 3D-FB72909

EZ-Link NHS-PEG12-Biotin

Prodotto controllato

CAS: 365441-71-0

Stability Moisture Sensitive
Applications EZ-Link NHS-PEG12-Biotin is a reactant in the preparation of biotin-CTT54 ligands and multivalent PSMA inhibitor-guided streptavidin conjugates for targeting prostate cancer cells.
References Liu, T., et. al.: Bioorg. Med. Chem. Lett., 22, 3931 (2012)

Formula: C₁₉H₂₈N₄O₇S

Colore e forma: Neat

Peso molecolare: 456.513

Ref: TR-N394010

NHS-dPEG®12 Biotin

CAS: 365441-71-0

NHS-dPEG®12 Biotin is a PEG compound with two different functional groups (also known as heterobifunctional). Unlike homobifunctional PEG compounds (same functional group on both ends), this type of compounds are more versatile as have two different anchor points. NHS-dPEG®12 Biotin is used as a linker and spacer to add a PEG moiety, via pegylation (a bioconjugation technique) to proteins, peptides, oligonucleotides, small molecules and nanoparticles.

Purezza: Min. 95%

Peso molecolare: 941.09 g/mol

Ref: 3D-DPG-5703

m-dPEG®4-Lipoamide

CAS: 365441-71-0

m-dPEG®4-Lipoamide is a PEG molecule conjugated with a lipid moiety. m-dPEG®4-Lipoamide, conjugated to this lipid constituent, is very important especially in drug delivery and vaccine development as it helps improve the stability and circulation time of lipid nanoparticles (LNPs) and liposomes.

Formula: C₄₁H₇₂N₄O₁₈S

Purezza: Min. 95%

Peso molecolare: 941.09 g/mol

Ref: 3D-DPG-6156