CAS 36791-04-5

Ribavirina

Descrizione:

Ribavirina è un farmaco antivirale utilizzato principalmente per trattare infezioni virali, in particolare l'epatite C e il virus respiratorio sinciziale (VRS). È classificato come un analogo dei nucleosidi, il che significa che imita i mattoni costitutivi dell'RNA e del DNA, interferendo così con la replicazione virale. La formula chimica di Ribavirina è C₁₁H₁₅N₄O₅P, e presenta una struttura simile alla guanosina che gli consente di inibire la sintesi dell'RNA virale. Ribavirina viene spesso somministrato in combinazione con altri agenti antivirali per aumentarne l'efficacia. La sostanza è tipicamente presentata come una polvere cristallina bianca o bianco sporco, solubile in acqua e leggermente solubile in alcol. Il suo meccanismo d'azione implica l'inibizione della RNA polimerasi virale e l'induzione di mutagenesi nei genomi virali, portando alla produzione di particelle virali difettose. Sebbene sia efficace, Ribavirina può avere effetti collaterali, tra cui anemia emolitica ed effetti teratogeni, richiedendo un attento monitoraggio durante il trattamento. A causa della sua azione specifica contro i virus a RNA, Ribavirina rimane un componente critico nella gestione di alcune infezioni virali.

Formula: C₈H₁₂N₄O₅

InChI: InChI=1S/C8H12N4O5/c9-6(16)7-10-2-12(11-7)8-5(15)4(14)3(1-13)17-8/h2-5,8,13-15H,1H2,(H2,9,16)/t3-,4-,5-,8-/m1/s1

InChI key: InChIKey=IWUCXVSUMQZMFG-AFCXAGJDSA-N

SMILES: O[C@H]1[C@@H](O[C@H](CO)[C@H]1O)N2N=C(C(N)=O)N=C2

Sinonimi:

• 1-Beta-D-Ribofuranosyl-1,2,4-Triazole-3-Carboxamide
• 1-[(2R,3R,4S,5R)-3,4-Dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-1H-1,2,4-triazole-3-carboxamide
• 1-pentofuranosyl-1H-1,2,4-triazole-3-carboxamide
• 1-β-<span class="text-smallcaps">D</span>-Ribofuranosyl-1,2,4-triazol-3-carboxyamide
• 1-β-<span class="text-smallcaps">D</span>-Ribofuranosyl-1,2,4-triazole-3-carboxamide
• 1-β-<span class="text-smallcaps">D</span>-Ribofuranosyl-1H-1,2,4-triazole-3-carboxamide
• 1-β-D-Ribofuranosyl-1,2,4-triazol-3-carboxyamide
• 1-β-D-ribofuranosyl-1,2,4-triazole-3-carboxamide
• 1H-1,2,4-Triazole-3-carboxamide, 1-β-<span class="text-smallcaps">D</span>-ribofuranosyl-
• 1H-1,2,4-Triazole-3-carboxamide, 1-β-D-ribofuranosyl-
• Biopolymers
• Copegus
• Cotronak
• Ebp 954
• Icn 1229
• Meduna
• MegaRibavirin
• Nsc 163039
• Ravanex
• Rebetol
• Ribamide
• Ribamidil
• Ribasphere
• Ribavarin
• Rtca
• Tribavirin
• Vilona
• Viramid
• Virazid
• Virazole
• Virin
• Virizadole

Ribavirin

CAS: 36791-04-5

Formula: C₈H₁₂N₄O₅

Purezza: >98.0%(HPLC)(N)

Colore e forma: White to Almost white powder to crystal

Peso molecolare: 244.21

Ref: 3B-R0077

Ribavirin

CAS: 36791-04-5

Ribavirin

Formula: C₈H₁₂N₄O₅

Purezza: 99.9%

Colore e forma: White Solid

Peso molecolare: 244.08077

Ref: 47-593

Ribavirin impurity standard

CAS: 36791-04-5, 39925-19-4

Ribavirin impurity standard

Colore e forma: White

Ref: 47-592

RIBAVIRIN CRS

CAS: 36791-04-5

RIBAVIRIN CRS

Formula: C₈H₁₂N₄O₅

Peso molecolare: 244.2047

Ref: 41-Y0000377

Ribavirin

CAS: 36791-04-5

Nucleic acids and their salts, whether or not chemically defined; other heterocyclic compounds, nesoi

Formula: C₈H₁₂N₄O₅

Colore e forma: White Crystalline Powder

Peso molecolare: 244.21 g/mol

Ref: 45-1602706

Ribavirin

CAS: 36791-04-5

Ribavirin (Tribavirin) is a synthetic nucleoside analog of ribofuranose with activity against hepatitis C virus and other RNA viruses.

Formula: C₈H₁₂N₄O₅

Purezza: 99.09% - 99.83%

Colore e forma: Less Solid Colourless Solid

Peso molecolare: 244.20

Ref: TM-T0684

1-β-D-Ribofuranosyl-1H-1,2,4-triazole-3-carboxamide

CAS: 36791-04-5

Formula: C₈H₁₂N₄O₅

Purezza: 98%

Colore e forma: Solid

Peso molecolare: 244.2047

Ref: IN-DA0039L3

Ribavirin

CAS: 36791-04-5

Formula: C₈H₁₂N₄O₅

Purezza: ≥ 98.0% (dried basis)

Colore e forma: White to off-white powder

Peso molecolare: 244.20

Ref: 7W-GA5462

Ribavirin

CAS: 36791-04-5

Ribavirin

Formula: C₈H₁₂N₄O₅

Purezza: 99.97% (Typical Value in Batch COA)

Colore e forma: white solid

Peso molecolare: 244.20g/mol

Ref: 54-BIB6306

Ribavirin

CAS: 36791-04-5

Ribavirin

Purezza: ≥98%

Peso molecolare: 244.2g/mol

Ref: 54-BUP17844

Ribavirin

CAS: 36791-04-5

Formula: C₈H₁₂N₄O₅

Colore e forma: Neat

Peso molecolare: 244.20

Ref: 04-C16813570

Ribavirin

Prodotto controllato

CAS: 36791-04-5

Formula: C₈H₁₂N₄O₅

Colore e forma: Neat

Peso molecolare: 244.20

Ref: 86-MM0542.00

Ribavirin 100 µg/mL in Acetonitrile:Methanol

Prodotto controllato

CAS: 36791-04-5

Formula: C₈H₁₂N₄O₅

Colore e forma: Single Solution

Peso molecolare: 244.20

Ref: 04-A16813570MC-100

Ribavirin-13C2

CAS: 36791-04-5

Formula: C₈H₁₂N₄O₅

Peso molecolare: 246.19

Ref: 4Z-R-041

Ribavirin RS

CAS: 36791-04-5

Colore e forma: White Solid Crystalline Powder

Ref: 2K-1181700021

Ribavirin

Prodotto controllato

CAS: 36791-04-5

Applications Purine nucleoside analog; inhibits inosine monophosphate dehydrogenase (IMPDH). Used as an antiviral agent.This compound is suitable for pyruvate dehydrogenase (PDH) related research.
References Fernandez, H., et al.: Eur. J. Epidemiol., 2, 1 (1986), Liao, H.J. and Stollar, V.: Antiviral Res., 22, 285 (1993), Honda, Y., et al.: Antimicrob. Agents Chemother., 38, 653 (1994), Reichard, O., et al.: Lancet, 351, 83 (1998)

Formula: C₈H₁₂N₄O₅

Colore e forma: White

Peso molecolare: 244.20

Ref: TR-R414475

Ribavirin

Prodotto controllato

CAS: 36791-04-5

Ribavirin is a guanosine nucleoside analog with broad-spectrum antiviral properties. Ribavirin gets phosphorylated to ribavirin triphosphate in cells and competes with natural nucleotides for incorporation in a nascent RNA chain, thus interfering with RNA synthesis by inhibiting viral RNA polymerases. Ribavirin is also an inhibitor of inosinate dehydrogenase (IMP), which is involved in the biosynthesis of GTP.

Formula: C₈H₁₂N₄O₅

Purezza: Min. 95%

Colore e forma: White Powder

Peso molecolare: 244.2 g/mol

Ref: 3D-NR02712

Ribavirin, Antibiotic for Culture Media Use Only

Prodotto controllato

CAS: 36791-04-5

Ribavirin is an antiviral agent used for the treatment of hepatitis C, respiratory syncytial virus infection and influenza. It is a monocarboxylic acid derived from vitamin B2. Ribavirin inhibits viral replication by interfering with the function of RNA polymerase. Ribavirin also has immunosuppressive properties that can be useful in treating autoimmune disorders such as systemic lupus erythematosus and it has been approved by the FDA for treatment of chronic hepatitis C virus (HCV) genotype 1 infection with compensated liver disease or decompensated liver disease with or without HCV genotype 3 infection. The antiviral activity of ribavirin against other viruses, including HIV-1, herpes simplex virus type 2, varicella zoster virus, cytomegalovirus, respiratory syncytial virus, influenza A and B viruses has been reported but not largely studied.

Formula: C₈H₁₂N₄O₅

Purezza: Min. 97.0 Area-%

Peso molecolare: 244.20 g/mol

Ref: 3D-Q-201670

Ribavirin

CAS: 36791-04-5

Formula: C₈H₁₂N₄O₅

Purezza: 98%

Colore e forma: Solid, White powder

Peso molecolare: 244.207

Ref: 10-F079125

Ribavirin

CAS: 36791-04-5

Colore e forma: Neat

Ref: 61-FOR0542.00