CAS 36951-72-1

5,10,15,20-Tetrakis(1-metil-4-piridinio)porfirina tetra(p-toluenosulfonato)

Descrizione:

5,10,15,20-Tetrakis(1-metil-4-piridinio)porfirina tetra(p-toluenosulfonato) è un composto di porfirina cationica caratterizzato dalla sua struttura complessa, che include un nucleo di porfirina sostituito con quattro gruppi 1-metil-4-piridinio. Questa sostituzione conferisce una solubilità significativa in solventi polari, rendendolo utile in varie applicazioni, tra cui la terapia fotodinamica e come colorante negli studi biologici. Il componente tetra(p-toluenosulfonato) migliora la sua solubilità e stabilità in ambienti acquosi. Il composto mostra una forte assorbimento nella regione visibile dello spettro elettromagnetico, in particolare nelle bande Soret e Q, che è tipico delle porfirine, permettendo il suo utilizzo in processi di raccolta della luce e fotochimici. Inoltre, la sua natura cationica può facilitare interazioni con molecole biologiche cariche negativamente, aumentando il suo potenziale per applicazioni terapeutiche. In generale, questo composto è notevole per le sue caratteristiche strutturali uniche e le sue applicazioni versatili sia nella ricerca che in contesti clinici.

Formula: C₄₄H₃₈N₈·4C₇H₇O₃S

InChI: InChI=1S/C44H37N8.C7H8O3S/c1-49-21-13-29(14-22-49)41-33-5-7-35(45-33)42(30-15-23-50(2)24-16-30)37-9-11-39(47-37)44(32-19-27-52(4)28-20-32)40-12-10-38(48-40)43(36-8-6-34(41)46-36)31-17-25-51(3)26-18-31;1-6-2-4-7(5-3-6)11(8,9)10/h5-28H,1-4H3,(H,45,46,47,48);2-5H,1H3,(H,8,9,10)/q+3;/b41-33-,41-34?,42-35-,42-37?,43-36-,43-38?,44-39-,44-40?;

InChI key: InChIKey=LZWDWCBCNUIVSC-JJUIXLEHSA-N

SMILES: C[N+]=1C=CC(C=2C=3NC(=CC3)C(=C4N=C(C=C4)C(=C5NC(=C(C6=NC2C=C6)C=7C=C[N+](C)=CC7)C=C5)C=8C=C[N+](C)=CC8)C=9C=C[N+](C)=CC9)=CC1.S(=O)(=O)([O-])C1=CC=C(C)C=C1

Sinonimi:

• 4,4',4'',4'''-Porphyrin-5,10,15,20-Tetrayltetrakis(1-Methylpyridinium)
• 5,10,15,20-Tetrakis(1-methyl-4-pyridinio)porphyrin tetra(p-toluenesulfonate)
• 5,10,15,20-Tetrakis(1-methyl-4-pyridyl)-21H,23H-porphine tetra-p-tosylate
• 5,10,15,20-Tetrakis(1-methylpyridinium-4-yl)porphyrin tetra(p-toluenesulfonate)
• 5,10,15,20-Tetrakis(1-methylpyridinium-4-yl)porphyrin tetratosylate
• 5,10,15,20-Tetrakis(N-methylpyridinium-4-yl)-21H,23H-porphine tetrakis(p-toluenesulfonate)
• 5,10,15,20-Tetrakis(N-methylpyridinium-4-yl)-21H,23H-porphyrin tetrakis(p-toluenesulfonate)
• 5,10,15,20-tetrakis(1-methyl-4-pyridyl)-21H,23H-P
• Pyridinium, 4,4′,4′′,4′′′-(21H,23H-porphine-5,10,15,20-tetrayl)tetrakis[1-methyl-, 4-methylbenzenesulfonate (1:4)
• Pyridinium, 4,4′,4′′,4′′′-(21H,23H-porphine-5,10,15,20-tetrayl)tetrakis[1-methyl-, salt with 4-methylbenzenesulfonic acid (1:4)
• TMPyP 4 4-methylbenzenesulfonate
• TMPyP 4 tosylate
• TMPyP [=alpha,,gamma,delta-Tetrakis(1-methylpiridinium-4-yl)porphine p-toluenesulfonate]
• TMPyP4 tetra(p-toluene sulfonate)
• Tetrakismethylpiridiniumylporphine
• Tmp 1363
• Tppt 4
• meso-Tetra(N-methyl-4-pyridinium)porphyrin tetratoluene-p-sulfonate
• meso-Tetrakis(1-methyl-4-pyridyl)porphyrin tetra(p-tosylate)
• meso-Tetrakis(1-methylpyridinium-4-yl)porphine p-toluenesulfonate
• meso-Tetrakis(N-methylpyridinium-4-yl)porphine tetratosylate

TMPyP [Ultra-high sensitive spectrophotometric reagent for Cu, Mg] [For the simultaneous determination of metals by HPLC]

CAS: 36951-72-1

Formula: C₇₂H₆₆N₈O₁₂S₄

Purezza: >98.0%(N)

Colore e forma: Dark red to Dark purple to Dark blue powder to crystal

Peso molecolare: 1,363.60

Ref: 3B-A5014

Tmpyp

CAS: 36951-72-1

Formula: C₇₂H₇₄N₈O₁₂S₄

Purezza: 97%

Colore e forma: Solid

Peso molecolare: 1371.6644

Ref: IN-DA003M8G

TMPyP4 tosylate

CAS: 36951-72-1

TMPyP4 tosylate

Purezza: ≥98%

Peso molecolare: 1363.6g/mol

Ref: 54-BUP11370

5,10,15,20-Tetrakis(1-Methyl-4-Pyridinio)Porphyrin Tetra(P-Toluenesulfonate)

CAS: 36951-72-1

5,10,15,20-Tetrakis(1-Methyl-4-Pyridinio)Porphyrin Tetra(P-Toluenesulfonate)

Purezza: 98%

Peso molecolare: 1,363.60g/mol

Ref: 54-OR1011741

meso-Tetra (N-methyl-4-pyridyl) porphine tetra tosylate

CAS: 36951-72-1

Formula: C₇₂H₆₆N₈O₁₂S₄

Purezza: >90%

Peso molecolare: 1363.61

Ref: FT-TMP-1363

TMPyP4 tosylate

CAS: 36951-72-1

TMPyP4 tosylate (TMP 1363) is a quadruplex-specific ligand and is a telomerase inhibitor with antitumor effects in osteosarcoma cell lines.

Formula: C₇₂H₆₆N₈O₁₂S₄

Purezza: 98.61% - 99.85%

Colore e forma: Solid

Peso molecolare: 1363.6

Ref: TM-T13174

TMPyP4

Prodotto controllato

CAS: 36951-72-1

Stability Hygroscopic, Light Sensitive
Applications TMPyP4 is a potent inhibitor of telomerase activity.
References Calvo, E. P., et al.: Mol. Biochem. Parasitol., 207, 33 (2016)

Formula: C₇₂H₆₆N₈O₁₂S₄

Colore e forma: Neat

Peso molecolare: 1363.6

Ref: TR-T460010

TMPyP4 tosylate

CAS: 36951-72-1

TMPyP4 tosylate is a chemical compound that is used in the treatment of bacterial infections. It is an active substance that can be used to prepare stable complexes with amines, which are then activated by intestinal enzymes. TMPyP4 tosylate has been shown to have binding activities towards telomeric DNA and gram-negative bacteria. This drug has been found to inhibit the growth of typhimurium, a gram-negative bacterium, by interacting with its ribosomal RNA and inhibiting protein synthesis.

Formula: C₇₂H₆₆N₈O₁₂S₄

Purezza: Min. 95%

Peso molecolare: 1,363.6 g/mol

Ref: 3D-LBA95172