CAS 379-79-3

tartrato di ergotamina

Descrizione:

tartrato di ergotamina è un composto farmaceutico derivato dagli alcaloidi dell'ergot, utilizzato principalmente nel trattamento delle emicranie. È un derivato semisintetico dell'ergotamina, che si ottiene dal fungo Claviceps purpurea. Questo composto è caratterizzato dalla sua capacità di costringere i vasi sanguigni, alleviando così i sintomi dell'emicrania. tartrato di ergotamina viene tipicamente somministrato sotto forma di compresse o formulazioni sublinguali, consentendo un rapido assorbimento e un inizio d'azione. La sostanza è nota per i suoi potenziali effetti collaterali, tra cui nausea, vomito e complicazioni cardiovascolari, in particolare quando usata in modo inappropriato o in dosi eccessive. Agisce principalmente come un agonista selettivo per i recettori della serotonina, in particolare i sottotipi 5-HT1B e 5-HT1D, che svolgono un ruolo cruciale nella regolazione del tono vascolare e nel rilascio di neurotrasmettitori. A causa delle sue proprietà farmacologiche, tartrato di ergotamina è classificato come sostanza controllata in alcune giurisdizioni, richiedendo un attento monitoraggio e prescrizione da parte di professionisti sanitari.

Formula: C₃₃H₃₅N₅O₅C₄H₆O₆

InChI: InChI=1S/C33H35N5O5.C4H6O6/c1-32(35-29(39)21-15-23-22-10-6-11-24-28(22)20(17-34-24)16-25(23)36(2)18-21)31(41)38-26(14-19-8-4-3-5-9-19)30(40)37-13-7-12-27(37)33(38,42)43-32;5-1(3(7)8)2(6)4(9)10/h3-6,8-11,15,17,21,25-27,34,42H,7,12-14,16,18H2,1-2H3,(H,35,39);1-2,5-6H,(H,7,8)(H,9,10)/t21-,25-,26+,27+,32-,33+;1-,2-/m11/s1

InChI key: InChIKey=NMTWKEWYQXZGCI-LYOWLMOVSA-N

SMILES: O[C@@]12N([C@@H](CC3=CC=CC=C3)C(=O)N4[C@]1(CCC4)[H])C(=O)[C@@](NC(=O)[C@@H]5C=C6C=7C=8C(C[C@]6(N(C)C5)[H])=CNC8C=CC7)(C)O2.[C@@H]([C@H](C(O)=O)O)(C(O)=O)O

Sinonimi:

• (5'Alpha)-5'-Benzyl-12'-Hydroxy-2'-Methyl-3',6',18-Trioxoergotaman 2,3-Dihydroxybutanedioate (1:1)
• (5'alpha)-12'-hydroxy-2'-methyl-5'-(phenylmethyl)-Ergotaman-3',6',18-trione, [R-(R*,R*)]-2,3-dihydroxybutanediate (2:1) (salt)
• Ergam
• Ergate
• Ergomar
• Ergostat
• Ergotaman-3',6',18-trione, 12'-hydroxy-2'-methyl-5'-(phenylmethyl)-, (5'alpha)-, [R-(R*,R*)]-2,3-dihydroxybutanedioate (2:1) (salt)
• Ergotaman-3′,6′,18-trione, 12′-hydroxy-2′-methyl-5′-(phenylmethyl)-, (5α)-, (2R,3R)-2,3-dihydroxybutanedioate (2:1)
• Ergotaman-3′,6′,18-trione, 12′-hydroxy-2′-methyl-5′-(phenylmethyl)-, (5′α)-, (2R,3R)-2,3-dihydroxybutanedioate (2:1) (salt)
• Ergotaman-3′,6′,18-trione, 12′-hydroxy-2′-methyl-5′-(phenylmethyl)-, (5′α)-, [R-(R*,R*)]-2,3-dihydroxybutanedioate (2:1) (salt)
• Ergotamine Bitartrate
• Ergotamine, tartrate (2:1) (salt)
• Ergotartrat
• Etin
• Exmigra
• Femergin
• Gotamine
• Gotamine tartrate
• Gynergen
• Gynergin
• Lingraine
• Lingran
• Medihaler-ergotamine
• NSC 41869
• Neo-Ergotin
• Rigetamin
• Secagyn
• Secupan
• Ergotamine tartrate
• ergotaminebitartrate
• ergotartrate
• 6’,18-trione,12’-hydroxy-2’-methyl-5’-(phenylmethyl)-ergotaman-3(5’alpha)
• -,[theta-(theta,theta)]-2,3-dihydroxybutanedioate(2:1)(salt)

Ergotamine Tartrate

Prodotto controllato

CAS: 379-79-3

Peso molecolare: 656.70

Ref: 3U-X8164

Ergotamine Tartrate

Prodotto controllato

CAS: 379-79-3

Colore e forma: Neat

Ref: 86-MM0097.00

Ergotamine D-Tartrate

Prodotto controllato

CAS: 379-79-3

Colore e forma: Neat

Ref: LP-ERG-803-TA-10

Ergotamine D-tartrate

Prodotto controllato

CAS: 379-79-3

Ergotamine D-tartrate is a drug that belongs to the group of nonsteroidal anti-inflammatory drugs. It is used in the treatment of migraine and other headaches. Ergotamine D-tartrate inhibits the production of nitric oxide, which has been shown to be involved in the process of angiogenesis. This drug also has long-term efficacy for headaches and migraines, as well as an anti-migraine effect. Ergotamine D-tartrate binds to specific receptors on neurons called alpha2 adrenergic receptors, which are located on blood vessels in the brain and have been implicated in migraine pathophysiology. These receptors are not present on vessels elsewhere in the body, which makes ergotamine a more selective drug for migraine than other nonsteroidal anti-inflammatory drugs.

Formula: (C₃₃H₃₅N₅O₅)₂•C₄H₆O₆

Purezza: Min. 95%

Peso molecolare: 1,313.44 g/mol

Ref: 3D-FE30656

ERGOTAMINE TARTRATE CRS - * DRUG PRECURSOR

Prodotto controllato

CAS: 379-79-3

ERGOTAMINE TARTRATE CRS - * DRUG PRECURSOR

Formula: C₇₀H₇₆N₁₀O₁₆

Colore e forma: Powder

Peso molecolare: 1313.41

Ref: 41-E1200000

ERGOTAMINE FOR SYSTEM SUITABILITY CRS - * DRUG PRECURSOR (ERGOTAMINE TARTRATE)

Prodotto controllato

CAS: 379-79-3

ERGOTAMINE FOR SYSTEM SUITABILITY CRS - * DRUG PRECURSOR (ERGOTAMINE TARTRATE)

Formula: C₇₀H₇₆N₁₀O₁₆

Colore e forma: Powder

Peso molecolare: 1313.41

Ref: 41-Y0001851

ERGOTAMINE TARTRATE RS - * DRUG PRECURSOR

Prodotto controllato

CAS: 379-79-3

ERGOTAMINE TARTRATE RS - * DRUG PRECURSOR

Formula: C₇₀H₇₆N₁₀O₁₆

Colore e forma: Powder

Peso molecolare: 1313.41

Ref: 41-ICRS0297

Ergotamine Tartrate

Prodotto controllato

CAS: 379-79-3

Ergotamine and its salts

Formula: (C₃₃H₃₅N₅O₅)₂·C₄H₆O₆

Colore e forma: White Yellow Powder

Peso molecolare: 1162.52764

Ref: 45-1241506

Ergotamine tartrate

Prodotto controllato

CAS: 379-79-3

Ergotamine tartrate

Colore e forma: White

Ref: 47-141