CAS 37921-38-3

Cimifugina

Descrizione:

Cimifugina è un composto naturale classificato come flavonoide, derivato principalmente dalle radici della pianta *Saposhnikovia divaricata*, comunemente utilizzato nella medicina tradizionale. È noto per le sue potenziali proprietà anti-infiammatorie, analgesiche e immunomodulatrici. La struttura chimica di Cimifugina presenta uno scheletro di cromone, caratteristico di molti flavonoidi, contribuendo alla sua attività biologica. Questo composto ha suscitato interesse nella ricerca farmacologica grazie alla sua capacità di modulare vari percorsi di segnalazione, offrendo potenzialmente benefici terapeutici in condizioni come l'artrite e altre malattie infiammatorie. Inoltre, Cimifugina mostra proprietà antiossidanti, che possono aiutare a proteggere le cellule dallo stress ossidativo. Il suo profilo di sicurezza e efficacia è oggetto di studi in corso, mentre i ricercatori esplorano le sue potenziali applicazioni nella medicina moderna. In generale, Cimifugina rappresenta un'area promettente di studio nel campo dei prodotti naturali e dei loro usi terapeutici.

Formula: C₁₆H₁₈O₆

InChI: InChI=1/C16H18O6/c1-16(2,19)13-5-9-11(22-13)6-12-14(15(9)20-3)10(18)4-8(7-17)21-12/h4,6,13,17,19H,5,7H2,1-3H3

InChI key: InChIKey=ATDBDSBKYKMRGZ-ZDUSSCGKSA-N

SMILES: O(C)C=1C2=C(C=C3C1C[C@@H](C(C)(C)O)O3)OC(CO)=CC2=O

Sinonimi:

• (2S)-2,3-Dihydro-7-(hydroxymethyl)-2-(1-hydroxy-1-methylethyl)-4-methoxy-5H-furo[3,2-g][1]benzopyran-5-one
• (2S)-7-(Hydroxymethyl)-2-(2-hydroxypropan-2-yl)-4-methoxy-2,3-dihydrofuro[3,2-g]chromen-5-one
• (2S)-7-(hydroxymethyl)-2-(2-hydroxypropan-2-yl)-4-methoxy-2,3-dihydro-5H-furo[3,2-g]chromen-5-one
• 2,3-Dihydro-7-hydroxymethyl-2-(1-hydroxy-1-methylethyl)-4-methoxy-5H-furo-[3,2-g]-[1]-benzopyran-5-one
• 5H-Furo[3,2-g][1]benzopyran-5-one, 2,3-dihydro-7-(hydroxymethyl)-2-(1-hydroxy-1-methylethyl)-4-methoxy-, (2S)-
• 5H-Furo[3,2-g][1]benzopyran-5-one, 2,3-dihydro-7-(hydroxymethyl)-2-(1-hydroxy-1-methylethyl)-4-methoxy-, (S)-
• 7-(hydroxymethyl)-2-(1-hydroxy-1-methylethyl)-4-methoxy-2,3-dihydro-5H-furo[3,2-g]chromen-5-one
• Cimitin
• Cimifugin
• Cimifugin, 98%, from Saposhnikovia divaricata (Turcz.) Schischk.
• CIMIFUGIN(P)
• (S)-2,3-Dihydro-7-(hydroxymethyl)-2-(1-hydroxy-1-methylethyl)-4-methoxy-5H-furo[3,2-g][1]benzopyran-5-one
• Cimifugin, 99.5%
• Cimifugin USP/EP/BP

Cimifugin

CAS: 37921-38-3

Aromatic heterocyclic compounds with oxygen hetero-atom(s) only, nesoi

Formula: C₁₆H₁₈O₆

Colore e forma: Light Yellow Off-White Powder

Peso molecolare: 306.11034

Ref: 45-1133828

CIMIFUGIN

CAS: 37921-38-3

Formula: C₁₆H₁₈O₆

Purezza: 98%

Colore e forma: Solid

Peso molecolare: 306.3105

Ref: IN-DA00BYG5

Cimifugin

CAS: 37921-38-3

Cimifugin

Purezza: ≥98%

Peso molecolare: 306.31g/mol

Ref: 54-BUP00157

Cimifugin

CAS: 37921-38-3

Formula: C₁₆H₁₈O₆

Peso molecolare: 306.31

Ref: 7W-GY1123

Cimifugin

CAS: 37921-38-3

Cimifugin, isolated from Peucedanum schottii, displays low to moderate inhibition towards AChE and BChE (3.12 and 21.63%, respectively) at 200 μg mL-1.

Formula: C₁₆H₁₈O₆

Purezza: 95%~99%

Colore e forma: Powder

Peso molecolare: 306.314

Ref: BP-BP0356

Cimifugin

CAS: 37921-38-3

Formula: C₁₆H₁₈O₆

Peso molecolare: 306.31

Ref: 4Z-C-500001

Cimifugin

CAS: 37921-38-3

Cimifugin blocks NO in LPS-stimulated RAW 264.7 cells and scavenges DPPH radicals.

Formula: C₁₆H₁₈O₆

Purezza: 99.62% - 99.87%

Colore e forma: Solid

Peso molecolare: 306.31

Ref: TM-T3383

Cimifugin

CAS: 37921-38-3

Oxygen-heterocyclic compound

Formula: C₁₆H₁₈O₆

Purezza: ≥ 98.0 % (HPLC)

Colore e forma: Powder

Peso molecolare: 306.32

Ref: 5G-89387

Cimifugin

CAS: 37921-38-3

Cimifugin is a compound extracted from the roots of Angelica Dahurica and Cimicifuga Foetida. It has been shown to have anti-inflammatory effects in rats, and may be useful in the treatment of arthritis. A pharmacokinetics study was conducted in mice, which showed that cimifugin is quickly metabolized into its active form, cimifuginol, after oral administration. The concentration–time curve for cimifugin shows that it has a short half-life (1 hour) and reaches its peak plasma concentration at 2 hours. Cimifugin also has an effect on platelet aggregation, with a potency similar to aspirin. It can be used as a medicine to treat pain and swelling caused by inflammation.

Formula: C₁₆H₁₈O₆

Purezza: Min. 95%

Colore e forma: White Powder

Peso molecolare: 306.31 g/mol

Ref: 3D-FC42575