CAS 38092-89-6

N-Metildesloratadina

Descrizione:

N-Metildesloratadina è un composto chimico che funge da metabolita attivo della desloratadina, un antistaminico utilizzato principalmente per il trattamento dei sintomi allergici. È caratterizzato dalla sua capacità di antagonizzare selettivamente i recettori H1 dell'istamina periferica, alleviando così sintomi come starnuti, naso che cola e occhi pruriginosi associati alla rinite allergica. Il composto è noto per le sue basse proprietà sedative, rendendolo adatto per l'uso in formulazioni non sonnolente. N-Metildesloratadina è tipicamente somministrato per via orale e presenta un profilo farmacocinetico favorevole, inclusa una buona biodisponibilità e una vita media relativamente lunga, che consente una somministrazione una volta al giorno. La sua struttura chimica include un anello di piperidina e un gruppo metile, contribuendo alla sua attività farmacologica. Inoltre, è generalmente ben tollerato, con una bassa incidenza di effetti collaterali rispetto agli antistaminici di prima generazione. Come per qualsiasi farmaco, è importante considerare le potenziali interazioni e controindicazioni quando si prescrive o si utilizza N-Metildesloratadina.

Formula: C₂₀H₂₁ClN₂

InChI: InChI=1/C20H21ClN2/c1-23-11-8-14(9-12-23)19-18-7-6-17(21)13-16(18)5-4-15-3-2-10-22-20(15)19/h2-3,6-7,10,13H,4-5,8-9,11-12H2,1H3

InChI key: InChIKey=VLXSCTINYKDTKR-UHFFFAOYSA-N

SMILES: ClC=1C=C2C(C(C=3C(CC2)=CC=CN3)=C4CCN(C)CC4)=CC1

Sinonimi:

• 5H-benzo[5,6]cyclohepta[1,2-b]pyridine, 8-chloro-6,11-dihydro-11-(1-methyl-4-piperidinylidene)-
• 8-Chloro-11-(1-methyl-4-piperidinylidene)-6,11-dihydro-5H-benzo[5,6]cyclohepta[1,2-b]pyridine
• 8-Chloro-11-(1-methylpiperidin-4-ylidene)-6,11-dihydro-5H-benzo[5,6]cyclohepta[1,2-b]pyridine
• Methyl loratadine
• N-Methyldesloratadine
• 8-Chloro-6,11-dihydro-11-(1-methyl-4-piperidinylidene)-5H-benzo[5,6]cyclohepta[1,2-b]pyridine
• 6,11ihydro-5H-Benzo-5,6Cyclohepta-L,2-BPyridine,Loratadine
• 8-Chloro-11-(1-Methyl-4-Piperidinylidene)-6, 11-dihydro 5H-Benzo [5,6] cyclohepta (1,2-b) Pyridine
• 8-CHLORO-11-(1-METHYL-4-PIPERIDINYLIDENE-6,11-DIHYDRO-5H-BNZO[5.6])CYCLOHEPTA[1,2-B]PYRIDINE
• 8-chloro-11-(1-methyl-4-piperidylidenel-5,11)-dihydro-5H-benzo5,6-cyclohepta
• 8-CHLORO-11-(L-METHYL-4-PIPERIDINYLIDENE-6,11-DIHYDRO-5H-BENZO[5.6])CYCLOHEPTA[L,2-B]PYRIDINE
• 8-CHLORO-6,11-DIHYDRO-11-(1-METHYL-4-PIPERIDINYLIDENE)-5H-BENZO[5,6] CYCLOHEPTA [1,2-B]PYRIDINE =99%
• 8-CHLORO AZATADINE
• 8-CHLORO-5,6-DIHYDRO-11H-BENZO[5,6]CYCLOHEPTO[1,2-B]PYRIDINE-11-ONE
• 8-CHLORO-11-(1-METHYL-4-PIPERIDYLIDENE)-6,11-DIHYDRO-5H-BENZO(5,6)CYCLOHEPTAL[1,2-B]PYRIDINE
• 8-chloro-11-(1-methyl-4-piperidylidenel-5,11)-dihydro-5H-benzo〔5,6〕-cyclohepta〔1,2-b〕pyridine
• 8-Chloro-11-(1-Methyl-4-Piperidylidene-5,11)-Dihydro-5h-Benzo(5,6)Cycloheptal[1,2-B]Pyridine
• 8-Chloro-11-(1-Methyl-4-Piperidylidene-5,11)-Dihydro-5h-Benzo(5,6)Cyclohepta[1,2-B]Pyridine
• 6,11 –Dihydro-5H-Benzo-5,6Cyclohepta-L,2-B Pyridine, Loratadine,

Loratadine Related Compound B (8-Chloro-5,6-dihydro-11-(N-methylpiperidin-4-ylidene)-11H-benzo[5,6]cyclohepta[1,2-b]pyridine)

CAS: 38092-89-6

Compounds containing an unfused pyridine ring in the structure, nesoi

Formula: C₂₀H₂₁ClN₂

Colore e forma: White Crystalline Powder

Peso molecolare: 324.13933

Ref: 45-1370291

8-chloro-11-(1-methylpiperidin-4-ylidene)-5,6-dihydrobenzo[1,2]cyclohepta[2,4-b]pyridine

CAS: 38092-89-6

Formula: C₂₀H₂₁ClN₂

Purezza: 97%

Colore e forma: Solid

Peso molecolare: 324.8471

Ref: IN-DA00I7I7

Loratadine EP Impurity G (Loratadine USP Related Compound B, Methyl Loratadine)

CAS: 38092-89-6

Formula: C₂₀H₂₁ClN₂

Colore e forma: Off-White Solid

Peso molecolare: 324.85

Ref: 4Z-L-1028

8-Chloro-11-[(n-methyl)-4-piperidylidene]-6,11-dihydro-5h-benzo [5,6] cyclohepta[1,2b]pyridine

CAS: 38092-89-6

8-Chloro-11-[(n-methyl)-4-piperidylidene]-6,11-dihydro-5h-benzo [5,6] cyclohepta[1,2b]pyridine

Formula: C₂₀H₂₁ClN₂

Purezza: 97%

Colore e forma: white powder

Peso molecolare: 324.85g/mol

Ref: 54-OR345568

8-Chloro-11-(1-methylpiperidin-4-ylidene)-6,11-dihydro-5H-benzo[5,6]cyclohepta[1,2-b]pyridine

Prodotto controllato

CAS: 38092-89-6

Formula: C₂₀H₂₁ClN₂

Colore e forma: Neat

Peso molecolare: 324.85

Ref: 86-MM0257.05

N-Methyl Desloratadine

Prodotto controllato

CAS: 38092-89-6

Formula: C₂₀H₂₁ClN₂

Colore e forma: Off-White

Peso molecolare: 324.85

Ref: TR-M316500

Loratadine EP Impurity G

CAS: 38092-89-6

Formula: C₂₀H₂₁ClN₂

Peso molecolare: 324.85

Ref: ST-EA-CP-L5007

N-Methyl Desloratadine

CAS: 38092-89-6

Formula: C₂₀H₂₁ClN₂

Peso molecolare: 324.85

Ref: ST-EA-CP-D15005

N-Methyl desloratadine

CAS: 38092-89-6

N-Methyl desloratadine is a molecule that is used as a template molecule for the preparation of samples. It is often used to measure the efficiency of extraction methods, such as high-performance liquid chromatography (HPLC) and gas chromatography (GC). The sample preparation process can be completed in less than one hour and requires only small amounts of reagents. N-Methyl desloratadine has been shown to be useful in detecting environmental pollution, such as diode, systematically. It also has been used to measure plasma levels of sodium citrate in human blood.

Formula: C₂₀H₂₁ClN₂

Purezza: Min. 95%

Peso molecolare: 324.85 g/mol

Ref: 3D-FM25484

N-Methyl Desloratadine

CAS: 38092-89-6

N-Methyl Desloratadine is a useful organic compound for research related to life sciences. The catalog number is T65952 and the CAS number is 38092-89-6.

Formula: C₂₀H₂₁ClN₂

Colore e forma: Solid

Peso molecolare: 324.85

Ref: TM-T65952