CAS 3810-74-0

Solfato di streptomicina

Descrizione:

Solfato di streptomicina è un antibiotico aminoglicosidico derivato dal batterio Streptomyces griseus. È utilizzato principalmente per trattare varie infezioni batteriche, in particolare quelle causate da Mycobacterium tuberculosis, rendendolo significativo nella terapia della tubercolosi. Il composto è caratterizzato dalla sua capacità di inibire la sintesi proteica batterica legandosi alla subunità ribosomiale 30S, interrompendo così il processo di traduzione. Solfato di streptomicina è una polvere cristallina bianca o leggermente gialla che è solubile in acqua, il che facilita la sua somministrazione per iniezione. Ha una formula molecolare che riflette la sua struttura complessa, inclusi più gruppi amminici e idrossilici. La forma solfato ne migliora la solubilità e la stabilità. Gli effetti collaterali comuni includono ototossicità e nefrotossicità, richiedendo un attento monitoraggio durante il trattamento. Solfato di streptomicina è anche notevole per il suo ruolo nello sviluppo della resistenza agli antibiotici, sottolineando l'importanza di un uso giudizioso in contesti clinici. Nel complesso, rimane un agente critico nell'arsenale contro alcune infezioni batteriche, in particolare nel contesto di ceppi multiresistenti.

Formula: C₂₁H₃₉N₇O₁₂H₂O₄S

InChI: InChI=1S/C21H39N7O12.H2O4S/c1-5-21(36,4-30)16(40-17-9(26-2)13(34)10(31)6(3-29)38-17)18(37-5)39-15-8(28-20(24)25)11(32)7(27-19(22)23)12(33)14(15)35;1-5(2,3)4/h4-18,26,29,31-36H,3H2,1-2H3,(H4,22,23,27)(H4,24,25,28);(H2,1,2,3,4)/t5-,6-,7+,8-,9-,10-,11+,12-,13-,14+,15+,16-,17-,18-,21+;/m0./s1

InChI key: InChIKey=CFCMMYICHMLDCC-RMIBZTJPSA-N

SMILES: S(=O)(=O)(O)O.O([C@H]1[C@H](O[C@@H]2[C@@H](NC(=N)N)[C@H](O)[C@@H](NC(=N)N)[C@H](O)[C@H]2O)O[C@@H](C)[C@@]1(C=O)O)[C@H]3[C@@H](NC)[C@H](O)[C@@H](O)[C@H](CO)O3

Sinonimi:

• 1,1'-[(1R,2R,3S,4R,5R,6S)-4-({5-deoxy-2-O-[2-deoxy-2-(methylamino)-alpha-L-glucopyranosyl]-3-C-formyl-alpha-L-lyxofuranosyl}oxy)-2,5,6-trihydroxycyclohexane-1,3-diyl]diguanidine sulfate (1:1)
• 2,2'-[(1R,2R,3S,4R,5R,6S)-4-({5-deoxy-2-O-[2-deoxy-2-(methylamino)-alpha-L-glucopyranosyl]-3-C-formyl-alpha-L-lyxofuranosyl}oxy)-2,5,6-trihydroxycyclohexane-1,3-diyl]diguanidine sulfate (2:3)
• <span class="text-smallcaps">D</smallcap>-Streptamine, O-2-deoxy-2-(methylamino)-α-<smallcap>L</smallcap>-glucopyranosyl-(1→2)-O-5-deoxy-3-C-formyl-α-<smallcap>L</span>-lyxofuranosyl-(1→4)-N,N′-bis(aminoiminomethyl)-, sulfate (2:3) (salt)
• <span class="text-smallcaps">D</smallcap>-Streptamine, O-2-deoxy-2-(methylamino)-α-<smallcap>L</smallcap>-glucopyranosyl-(1→2)-O-5-deoxy-3-C-formyl-α-<smallcap>L</span>-lyxofuranosyl-(1→4)-N¹,N³-bis(aminoiminomethyl)-, sulfate (2:3)
• Ag Streptomycin
• Agri-Strep
• Agrimycin 17
• Agrimycin sulfate
• Ambistryn
• Ambistryn S
• D-Streptamine, O-2-deoxy-2-(methylamino)-α-L-glucopyranosyl-(1→2)-O-5-deoxy-3-C-formyl-α-L-lyxofuranosyl-(1→4)-N,N'-bis(aminoiminomethyl)-, sulfate (2:3) (salt)
• D-Streptamine, O-2-deoxy-2-(methylamino)-α-L-glucopyranosyl-(1→2)-O-5-deoxy-3-C-formyl-α-L-lyxofuranosyl-(1→4)-N1,N3-bis(aminoiminomethyl)-, sulfate (2:3)
• FireWall (pesticide)
• Flare 72SP
• Hortocyna
• KeyStrepto
• N'',N'''''-[(1R,2R,3S,4R,5R,6S)-4-({(2xi)-5-deoxy-2-O-[2-deoxy-2-(methylamino)-alpha-L-glucopyranosyl]-3-C-formyl-alpha-L-threo-pentofuranosyl}oxy)-2,5,6-trihydroxycyclohexane-1,3-diyl]diguanidine sulfate (salt)
• N'',N'''''-[(1S,2S,3R,4S,5S,6R)-4-({5-deoxy-2-O-[2-deoxy-2-(methylamino)-α-L-glucopyranosyl]-3-C-formyl-α-L-lyxofuranosyl}oxy)-2,5,6-trihydroxycyclohexane-1,3-diyl]diguanidine sulfate (2:3) (salt)
• O-2-Deoxy-2-(Methylamino)-Alpha-L-Glucopyranosyl-(1->2)-O-5-Deoxy-3-C-Formyl-Alpha-L-Lyxofuranosyl-(1->4)-N,N'-Bis(Aminoiminomethyl)-Streptamine Sulfate (2:3)
• O-2-Deoxy-2-(methylamino)-α-L-glucopyranosyl-(1→2)-O-5-deoxy-3-c-formyl-α-L-lyxofuranosyl-(1→4)-N,N'-bis(aminoiminomethyl)-D-streptamine sulfate (2:3)
• Plantomycin
• Strepto
• Streptobrettin
• Streptomycin A sulfate
• Streptomycin Sesquisulfate
• Streptomycin Sulfate Sterile
• Streptomycin sesquisulphate
• Streptomycin sulphate
• Streptomycin, sulfate (2:3) (salt)
• Streptomycinsulfat
• Streptonex
• Strycin
• Sulfate de streptomycine
• Sulfato De Estreptomicina
• Vetstrep

Streptomycin sulfate, Antibiotic for Culture Media Use Only

CAS: 3810-74-0

Streptomycin sulfate is an antibiotic that inhibits the growth of bacteria by binding to the ribosomal subunit and interfering with protein synthesis. It is used in culture media for the production of human antibodies as well as in drug therapy for methicillin-resistant staphylococcus. Streptomycin sulfate has a high specific activity and low sensitivity, but it also has a low solubility in water. The active form of streptomycin sulfate is streptomycin A, which is produced by the addition of a phenyl ring to neomycin sulfate. In plant roots, streptomycin sulfate inhibits cyanogenic glycosides from being hydrolyzed into hydrogen cyanide (HCN) and benzaldehyde.

Formula: C₄₂H₈₄N₁₄O₃₆S₃

Peso molecolare: 1,457.40 g/mol

Ref: 3D-S-8500

Streptomycin sulfate

CAS: 3810-74-0

Inhibitor of protein synthesis; aminoglycoside

Formula: (C₂₁H₃₉N₇O₁₂)₂•(H₂SO₄)₃

Purezza: Min. 720 Iu/Mg

Colore e forma: White Off-White Powder

Peso molecolare: 1,457.39 g/mol

Ref: 3D-AS01530

Streptomycin Sulphate (STM)

CAS: 3810-74-0

Formula: (C₂₁H₃₉N₇O₁₂)₂·3H₂SO₄

Colore e forma: White to off - white, Crystalline powder, Clear, Pale yellow

Peso molecolare: 1457.38

Ref: SR-91014

Streptomycin Sulphate for tissue culture

CAS: 3810-74-0

Formula: (C₂₁H₃₉N₇O₁₂)₂·3H₂SO₄

Colore e forma: White to off - white, Crystalline powder, Clear, Pale yellow

Peso molecolare: 1457.38

Ref: SR-62463