CAS 382-67-2

Desossimetasone

Descrizione:

Desossimetasone è un corticosteroide sintetico utilizzato principalmente per le sue proprietà anti-infiammatorie e immunosoppressive nelle applicazioni dermatologiche. È caratterizzato dalla sua capacità di ridurre l'infiammazione, il prurito e il rossore associati a varie condizioni della pelle, come eczema e psoriasi. Il composto presenta un'alta potenza rispetto ad altri corticosteroidi topici, rendendolo efficace nel trattamento di disturbi cutanei da moderati a gravi. Desossimetasone è tipicamente formulato in preparazioni topiche, comprese creme e unguenti, consentendo un trattamento localizzato con un'assorbimento sistemico minimo. Il suo meccanismo d'azione implica l'inibizione dei mediatori infiammatori e la modulazione delle risposte immunitarie. La sostanza è generalmente ben tollerata, sebbene gli effetti collaterali potenziali possano includere irritazione della pelle, atrofia o effetti sistemici con uso prolungato. Come con tutti i corticosteroidi, è importante utilizzare Desossimetasone sotto supervisione medica per minimizzare i rischi e garantire risultati terapeutici appropriati.

Formula: C₂₂H₂₉FO₄

InChI: InChI=1S/C22H29FO4/c1-12-8-16-15-5-4-13-9-14(25)6-7-21(13,3)22(15,23)18(27)10-20(16,2)19(12)17(26)11-24/h6-7,9,12,15-16,18-19,24,27H,4-5,8,10-11H2,1-3H3/t12-,15+,16+,18+,19-,20+,21+,22+/m1/s1

InChI key: InChIKey=VWVSBHGCDBMOOT-IIEHVVJPSA-N

SMILES: F[C@@]12[C@]([C@]3([C@](C)(C[C@@H]1O)[C@@H](C(CO)=O)[C@H](C)C3)[H])(CCC=4[C@]2(C)C=CC(=O)C4)[H]

Sinonimi:

• (11Beta,16Alpha)-9-Fluoro-11,21-Dihydroxy-16-Methylpregna-1,4-Diene-3,20-Dione
• (11β,16α)-9-Fluoro-11,21-dihydroxy-16-methylpregna-1,4-diene-3,20-dione
• (16Alpha)-9-Fluoro-11,21-Dihydroxy-16-Methylpregna-1,4-Diene-3,20-Dione
• (8Xi,10Xi,13Xi,14Xi,16Alpha,17Xi)-9-Fluoro-11,21-Dihydroxy-16-Methylpregna-1,4-Diene-3,20-Dione
• 17-Deoxydexamethasone
• 17-Deoxymethansone
• 17-Deoxymethasone
• 17-Desoximethasone
• 9-Fluoro-11-beta,21-dihydroxy-16-alpha-methylpregna-1,4-diene-3,20-dione
• 9-Fluoro-11beta,21-dihydroxy-16alpha-methylpregna-1,4-diene-3,20-dione
• 9-Fluoro-16α-methyl-Δ1-corticosterone
• 9-Fluoro-16α-methyl-Δ¹-corticosterone
• 9α-Fluoro-11β,21-dihydroxy-16α-methylpregna-1,4-diene-3,20-dione
• A 41-304
• A 41304
• Brn 2228097
• Deoxymethasone
• Desossimetasone
• Desossimetasone [DCIT]
• Desoximetason
• Desoximetasona
• Desoximetasona [INN-Spanish]
• Desoximetasone [USAN:INN]
• Desoximetasonum
• Desoximetasonum [INN-Latin]
• Desoximethasone
• Desoxymetasone
• Desoxymethasone
• Esperson
• Flubason
• Hoe 304
• Ibaril
• Pregna-1,4-diene-3,20-dione, 9-fluoro-11,21-dihydroxy-16-methyl-, (11beta,16alpha)-
• Pregna-1,4-diene-3,20-dione, 9-fluoro-11,21-dihydroxy-16-methyl-, (11β,16α)-
• Pregna-1,4-diene-3,20-dione, 9-fluoro-11β,21-dihydroxy-16α-methyl-
• R 2113
• Stidex
• Stiedex
• Topicort
• Topicort LP
• Topicorte
• Topisolon

Desoximetasone

CAS: 382-67-2

Formula: C₂₂H₂₉FO₄

Purezza: >97.0%(HPLC)

Colore e forma: White to Almost white powder to crystal

Peso molecolare: 376.47

Ref: 3B-D5515

Desoximetasone

CAS: 382-67-2

Halogenated derivatives of adrenal cortical hormones

Formula: C₂₂H₂₉FO₄

Colore e forma: White Powder

Peso molecolare: 376.20499

Ref: 45-1173508

Desoximetasone (Dexamethasone EP Impurity F)

CAS: 382-67-2

Formula: C₂₂H₂₉FO₄

Colore e forma: White To Off-White Solid

Peso molecolare: 376.47

Ref: 4Z-D-113001

Desoximetasone

CAS: 382-67-2

Formula: C₂₂H₂₉FO₄

Purezza: ≥ 97.0%

Colore e forma: White to off-white crystalline powder

Peso molecolare: 376.46

Ref: 7W-GX4795

Desoximetasone-d3 (Dexamethasone EP Impurity F-d3)

CAS: 382-67-2

Formula: C₂₂H₂₆D₃FO₄

Colore e forma: White To Off-White Solid

Peso molecolare: 379.49

Ref: 4Z-D-113002

Desoximetasone

CAS: 382-67-2

Desoximetasone

Purezza: ≥98%

Peso molecolare: 376.46g/mol

Ref: 54-BUP13711

Desoximetasone

CAS: 382-67-2

Purezza: 98%

Peso molecolare: 376.4679870605469

Ref: 10-F787595

Desoxymetasone

CAS: 382-67-2

Formula: C₂₂H₂₉FO₄

Colore e forma: Neat

Peso molecolare: 376.46

Ref: 04-C12170160

9-Fluoro-11β,21-dihydroxy-16α-methylpregna-1,4-diene-3,20-dione

Prodotto controllato

CAS: 382-67-2

Formula: C₂₂H₂₉FO₄

Colore e forma: White To Off-White

Peso molecolare: 376.46

Ref: 86-MM0213.06

Desoximetasone

CAS: 382-67-2

Desoximetasone (Topicort) is a topical corticosteroid for treating skin conditions like rashes.

Formula: C₂₂H₂₉FO₄

Purezza: 99.06% - 99.89%

Colore e forma: Solid

Peso molecolare: 376.46

Ref: TM-T4572

Desoxymetasone

CAS: 382-67-2

Applications Glucocorticoid anti-inflammatory. It is also found as an impurity in Dexamethasone (D298800).
References Schriks, M., et al.: Environ. Sci. Technol., 44, 4766 (2010), Baeck, M., et al.: Eur. J. Dermatol., 20, 102 (2010), Lee, P., et al.: Bioorg. Med. Chem. Lett., 20, 69 (2010),

Formula: C₂₂H₂₉FO₄

Colore e forma: White To Off-White

Peso molecolare: 376.46

Ref: TR-D296970

Dexamethasone EP Impurity F

CAS: 382-67-2

Formula: C₂₂H₂₉FO₄

Peso molecolare: 376.47

Ref: ST-EA-CP-D17006

Desoxymetasone-D5 (Major)

Prodotto controllato

CAS: 382-67-2

Applications Desoxymetasone-D5 is a labelled analogue of Desoxymetasone (D296970). Desoxymetasone is a fluorinated corticosteroid that is structurally related to Dexamethasone (D298800), and is used as a topical cream to treat eczema.
References Heel, R., et al.: Drugs, 16, 302 (1978); Henry, M., et al.: Curr. Med. Res. Opin., 6, 502 (1980); Sehgal, Int. J. Derm., 15, 770 (1976)

Formula: C₂₂D₅H₂₄FO₄

Colore e forma: Neat

Peso molecolare: 381.49

Ref: TR-D296972

Desoximetasone Carboxylic Acid

Prodotto controllato

CAS: 382-67-2

Formula: C₂₂H₂₇FO₅

Colore e forma: Neat

Peso molecolare: 390.445

Ref: TR-D397730

Desfluoro Chloro Desoximetasone

Prodotto controllato

CAS: 382-67-2

Applications Desfluoro Chloro Desoximetasone is an impurity of Desoxymetasone (D296970) which is anti-inflammatory.
References Schriks, M., et al.: Environ. Sci. Technol., 44, 4766 (2010), Baeck, M., et al.: Eur. J. Dermatol., 20, 102 (2010), Lee, P., et al.: Bioorg. Med. Chem. Lett., 20, 69 (2010),

Formula: C₂₂H₂₉ClO₄

Colore e forma: Neat

Peso molecolare: 392.916

Ref: TR-D118899

9-Fluoro-11b,21-dihydroxy-16a-methylpregna-1,4-diene-3,20-dione

Prodotto controllato

CAS: 382-67-2

9-Fluoro-11b,21-dihydroxy-16a-methylpregna-1,4-diene-3,20-dione is a potent antiandrogen that is used to treat alopecia areata and other skin disorders. 9-Fluoro-11b,21-dihydroxy-16a-methylpregna-1,4-diene-3,20-dione has been shown to have an inhibitory effect on the growth of skin tumors in mice. This drug also has a protective effect against chemical stability. It binds to fatty acids and epidermal growth factor (EGF), which may be related to its ability to regulate transcriptional processes and inflammatory skin diseases.

Formula: C₂₂H₂₉FO₄

Purezza: Min. 95%

Peso molecolare: 376.46 g/mol

Ref: 3D-FF21375