CAS 38243-03-7

R-Ginsenoside Rg3

Descrizione:

R-Ginsenoside Rg3 è un composto naturale derivato dal ginseng, specificamente un tipo di ginsenoside, che sono saponine steroidee conosciute per le loro varie proprietà farmacologiche. È caratterizzato dalla sua formula molecolare, che riflette la sua struttura complessa, presentando tipicamente uno scheletro steroideo con moieties di zucchero. Rg3 esiste in due forme stereoisomeriche, con la forma R biologicamente attiva. Questo composto è riconosciuto per i suoi potenziali benefici per la salute, inclusi effetti antitumorali, anti-infiammatori e neuroprotettivi. Rg3 è stato studiato per la sua capacità di modulare vari percorsi biologici, inclusi apoptosi e proliferazione cellulare, rendendolo di interesse sia nella medicina tradizionale che nella farmacologia moderna. Inoltre, è spesso esplorato nel contesto del miglioramento della funzione immunitaria e del miglioramento della vitalità generale. La sua solubilità e stabilità possono variare in base alla formulazione e alle condizioni, che sono considerazioni importanti per la sua applicazione in integratori alimentari e agenti terapeutici. In generale, R-Ginsenoside Rg3 rappresenta un'area significativa di ricerca nella chimica dei prodotti naturali e nelle applicazioni medicinali.

Formula: C₄₂H₇₂O₁₃

InChI: InChI=1S/C42H72O13/c1-21(2)10-9-14-42(8,51)22-11-16-41(7)29(22)23(45)18-27-39(5)15-13-28(38(3,4)26(39)12-17-40(27,41)6)54-37-35(33(49)31(47)25(20-44)53-37)55-36-34(50)32(48)30(46)24(19-43)52-36/h10,22-37,43-51H,9,11-20H2,1-8H3/t22-,23+,24+,25+,26-,27+,28-,29-,30+,31+,32-,33-,34+,35+,36-,37-,39-,40+,41+,42+/m0/s1

InChI key: InChIKey=RWXIFXNRCLMQCD-CZIWJLDFSA-N

SMILES: C[C@]12[C@@]3(C)[C@@]([C@@]([C@](CCC=C(C)C)(C)O)(CC3)[H])([C@H](O)C[C@@]1([C@]4(C)[C@@](CC2)(C(C)(C)[C@@H](O[C@H]5[C@H](O[C@@H]6O[C@H](CO)[C@@H](O)[C@H](O)[C@H]6O)[C@@H](O)[C@H](O)[C@@H](CO)O5)CC4)[H])[H])[H]

Sinonimi:

• (20S)-Propanaxadiol
• (2S,3R,4S,5S,6R)-2-[(2R,3R,4S,5S,6R)-4,5-dihydroxy-2-[[(10R,12S,13R,14R,17S)-12-hydroxy-17-[(2R)-2-hydroxy-6-methylhept-5-en-2-yl]-4,4,10,13,14-pentamethyl-2,3,5,6,7,8,9,11,12,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthren-3-yl]oxy]-6-(hydroxymethyl)oxa
• (3Beta,12Beta)-12,20-Dihydroxydammar-24-En-3-Yl 2-O-Beta-D-Glucopyranosyl-Beta-D-Glucopyranoside
• (3β,12β,20R)-12,20-Dihydroxydammar-24-en-3-yl 2-O-β-<span class="text-smallcaps">D</smallcap>-glucopyranosyl-β-<smallcap>D</span>-glucopyranoside
• (3β,12β,20R)-12,20-Dihydroxydammar-24-en-3-yl O-β-<span class="text-smallcaps">D</smallcap>-glucopyranosyl-(1→2)-β-<smallcap>D</span>-glucopyranoside
• (5xi,8xi,9xi,12alpha,14beta,20R)-12,20-dihydroxylanost-24-en-3-yl 2-O-beta-D-glucopyranosyl-beta-D-glucopyranoside
• (8xi,9xi,12alpha,14beta,17alpha)-12-hydroxy-17-[(2S)-2-hydroxy-6-methylhept-5-en-2-yl]-4,4,10,14-tetramethylgonan-3-yl 2-O-[3-deoxy-3-(hydroxymethyl)-beta-D-glucopyranosyl]-beta-D-glucopyranoside
• 20(R)-Ginsenoside Rg₃
• 20(R)-Propanaxadiol
• 20(S)-Ginsenoside-Rg3
• 20R-Ginsenoside Rg3
• Beta-D-Glucopyranoside,(3-Beta,12-Beta)-12,20-Dihydroxydammar-24-En-3-Yl2-O-B
• Dammar-24-Ene-12-Beta,20-Diol,3-Beta-((2-O-Beta-D-Glucopyranosyl-Beta-D-Gluc
• Dammar-24-ene-12β,20-diol, 3β-[(2-O-β-D-
• Eta-D-Glucopyranosyl-
• Ginsenoside rg3(R)
• Opyransoyl)Oxy)-
• R-Ginsenoside Rg₃
• beta-D-Glucopyranoside,(3beta,12beta)-12,20-dihydroxydammar-24-en-3-yl 2-O-beta-D-glucopyranosyl
• β-<span class="text-smallcaps">D</smallcap>-Glucopyranoside, (3β,12β,20R)-12,20-dihydroxydammar-24-en-3-yl 2-O-β-<smallcap>D</span>-glucopyranosyl-
• (3β,12β,20R)-12,20-Dihydroxydammar-24-en-3-yl 2-O-β-D-glucopyranosyl-β-D-glucopyranoside
• 20(R)-Ginsenoside Rg3
• (3β,12β,20R)-12,20-Dihydroxydammar-24-en-3-yl O-β-D-glucopyranosyl-(1→2)-β-D-glucopyranoside

20(R)-Propanaxadiol

CAS: 38243-03-7

Ref: 7W-GC5327

(20R)-Ginsenoside Rg3

CAS: 38243-03-7

(20R)-Ginsenoside Rg3

Purezza: ≥95%

Peso molecolare: 785.01g/mol

Ref: 54-BUP00028

20(R)-Ginsenoside Rg3

CAS: 38243-03-7

20(R)-Ginsenoside Rg3 has shown multiple pharmacological activities and been considered as one of the most promising approaches for fatigue treatment, however, 20(R)-Ginsenoside Rg3 has a low bioavailability after oral administration in human, so, 20(R)-Rg3 can be by intranasal administration, the mechanism was related to the increase of the storage of hepatic glycogen, and the decrease of the accumulation of metabolite such as lactic acid and serum urea nitrogen.

Formula: C₄₂H₇₂O₁₃

Purezza: 95%~99%

Colore e forma: White powder

Peso molecolare: 785.025

Ref: BP-BP0040

20(R)-Ginsenoside Rg3

CAS: 38243-03-7

Formula: C₄₂H₇₂O₁₃

Purezza: >97.0%(HPLC)

Colore e forma: White to Light yellow powder to crystal

Peso molecolare: 785.03

Ref: 3B-G0536

(20R)-Ginsenoside Rg3

CAS: 38243-03-7

(20R)-Ginsenoside Rg3 (20(R)-Propanaxadiol) is a compound with anti-aging and antifatigue activities.

Formula: C₄₂H₇₂O₁₃

Purezza: 97.03% - 99.67%

Colore e forma: Solid

Peso molecolare: 785.01

Ref: TM-T3812

20(R)-Ginsenoside Rg3

Prodotto controllato

CAS: 38243-03-7

Applications 20(R)-Ginsenoside Rg3 causes an inhibition of phosphatidylinositol 3-kinase/Akt activation that, in turn, results in modulations in Bcl-2 family proteins in such a way that the apoptosis of U87 cells are regulated. Elicits a significant inhibition of in vitro cell adhesion and invasion of U87 cells. in vitro stereoselective inhibition of ginsenosides toward UDP-glucuronosyltransferase isoforms and in vivo inhibition of tumor angiogenesis of lung cancer.
References Liu, Y., et al.: Chengdu Yixueyuan Xuebao, 9, 4 (2014); Liu, Y., et al.: Linchuang Junyi Zazhi, 42, 1138 (2014), Kim, D., et al.: Toxicol. Lett., 259, 1 92016); Geng, L., et al.: Zhonghua Zhongyiyao Zazhi, 29, 601 (2014)

Formula: C₄₂H₇₂O₁₃

Colore e forma: Neat

Peso molecolare: 785.01

Ref: TR-G387625

(20R)-Ginsenoside Rg3

CAS: 38243-03-7

(20R)-Ginsenoside Rg3 is a triterpenoid saponin, which is a bioactive compound isolated from the root of Panax ginseng. This product is an integral part of traditional medicine and is now being extensively studied in modern pharmacological research. As a ginsenoside, Rg3 exerts its effects primarily by modulating cellular pathways, inhibiting angiogenesis, and inducing apoptosis in cancer cells.

Formula: C₄₂H₇₂O₁₃

Purezza: Min. 95%

Colore e forma: Powder

Peso molecolare: 785.01 g/mol

Ref: 3D-OG15964

20(R)-Ginsenoside Rg3-d6

Prodotto controllato

CAS: 38243-03-7

Formula: C₄₂D₆H₆₆O₁₃

Colore e forma: Neat

Peso molecolare: 791.05

Ref: TR-G410288

20(R)-Propanaxadiol

CAS: 38243-03-7

Formula: C₄₂H₇₂O₁₃

Colore e forma: Solid

Peso molecolare: 785.0133

Ref: IN-DA00BXSG