CAS 3847-29-8

Lattobionato di eritromicina

Descrizione:

Lattobionato di eritromicina è un antibiotico macrolide derivato dal batterio Saccharopolyspora erythraea. È utilizzato principalmente per trattare varie infezioni batteriche, in particolare quelle causate da batteri Gram-positivi e alcuni organismi Gram-negativi. La sostanza è caratterizzata dalla sua forma di sale lattobionato, che ne migliora la solubilità in acqua, rendendola adatta per somministrazione endovenosa. Lattobionato di eritromicina mostra un ampio spettro di attività contro le infezioni delle vie respiratorie, le infezioni della pelle e alcune malattie sessualmente trasmissibili. Il suo meccanismo d'azione implica l'inibizione della sintesi proteica batterica legandosi alla subunità ribosomiale 50S, impedendo così la crescita e la riproduzione dei batteri. Il composto è generalmente ben tollerato, sebbene possa causare effetti collaterali gastrointestinali e abbia potenziali interazioni con altri farmaci a causa del suo effetto sugli enzimi epatici. Come per tutti gli antibiotici, un uso appropriato è cruciale per prevenire lo sviluppo di resistenza agli antibiotici.

Formula: C₃₇H₆₇NO₁₃·C₁₂H₂₂O₁₂

InChI: InChI=1S/C37H67NO13.C12H22O12/c1-14-25-37(10,45)30(41)20(4)27(39)18(2)16-35(8,44)32(51-34-28(40)24(38(11)12)15-19(3)47-34)21(5)29(22(6)33(43)49-25)50-26-17-36(9,46-13)31(42)23(7)48-26;13-1-3(15)10(7(18)8(19)11(21)22)24-12-9(20)6(17)5(16)4(2-14)23-12/h18-26,28-32,34,40-42,44-45H,14-17H2,1-13H3;3-10,12-20H,1-2H2,(H,21,22)/t18-,19-,20+,21+,22-,23+,24+,25-,26+,28-,29+,30-,31+,32-,34+,35-,36-,37-;3-,4-,5+,6+,7-,8-,9-,10-,12+/m11/s1

InChI key: InChIKey=NNRXCKZMQLFUPL-WBMZRJHASA-N

SMILES: O([C@@H]1[C@@H](C)[C@H](O[C@H]2C[C@](OC)(C)[C@@H](O)[C@H](C)O2)[C@@H](C)C(=O)O[C@H](CC)[C@@](C)(O)[C@H](O)[C@@H](C)C(=O)[C@H](C)C[C@@]1(C)O)[C@H]3[C@H](O)[C@@H](N(C)C)C[C@@H](C)O3.[C@H](O[C@@H]1O[C@H](CO)[C@H](O)[C@H](O)[C@H]1O)([C@@H]([C@H](C(O)=O)O)O)[C@@H](CO)O

Sinonimi:

• (2R,3R,4R,5R)-2,3,5,6-tetrahydroxy-4-{[(2S,3R,4S,5R,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl]oxy}hexanoic acid - (3R,4S,5S,6R,7R,9R,11R,12R,13S,14R)-6-{[(2S,3R,4S,6R)-4-(dimethylamino)-3-hydroxy-6-methyltetrahydro-2H-pyran-2-yl]oxy}-14-ethyl-7,12,13-trihydroxy-4-{[(2R,4R,5S,6S)-5-hydroxy-4-methoxy-4,6-dimethyltetrahydro-2H-pyran-2-yl]oxy}-3,5,7,9,11,13-hexamethyloxacyclotetradecane-2,10-dione (1:1) (non-preferred name)
• 4-O-beta-D-Galactopyranosyl-D-gluconic acid compd. with erythromycin
• <span class="text-smallcaps">D</smallcap>-Gluconic acid, 4-O-β-<smallcap>D</span>-galactopyranosyl-, compd. with erythromycin (1:1)
• D-Gluconic acid, 4-O-beta-D-galactopyranosyl-, compd. with erythromycin (1:1) (9CI)
• Erythrocin Lactobionate IV
• Erythrocin lactobionate
• Erythromycin lactobionate (1:1) (salt)
• Erythromycin mono(4-O-beta-D-galactopyranosyl-D-gluconate) (salt)
• Erythromycin, 4-O-beta-D-galactopyranosyl-D-gluconate (salt)
• Erythromycin, 4-O-β-<span class="text-smallcaps">D</smallcap>-galactopyranosyl-<smallcap>D</span>-gluconate (1:1)
• Erythromycin, 4-O-β-<span class="text-smallcaps">D</smallcap>-galactopyranosyl-<smallcap>D</span>-gluconate (salt)
• Erythromycin. compd. with lactobionic acid
• Lactobionic acid, compd. with erythromycin (1:1)
• Oxacyclotetradecane, erythromycin deriv.
• Erythromycin, 4-O-β-D-galactopyranosyl-D-gluconate (1:1)

ERYTHROMYCIN LACTOBIONATE CRS

CAS: 3847-29-8

ERYTHROMYCIN LACTOBIONATE CRS

Formula: C₄₉H₈₉NO₂₅

Peso molecolare: 1092.223

Ref: 41-Y0001848

Erythromycin Lactobionate

CAS: 3847-29-8

Erythromycin and its derivatives; salts thereof

Formula: C₃₇H₆₇NO₁₃·C₁₂H₂₂O₁₂

Colore e forma: White Off-White Powder

Peso molecolare: 1091.57237

Ref: 45-1247003

Erythromycin Lactobionate

CAS: 3847-29-8

Formula: C₄₉H₈₉NO₂₅

Purezza: 98%

Colore e forma: Solid

Peso molecolare: 1092.2227

Ref: IN-DA0079PQ

Erythromycin lactobionate

CAS: 3847-29-8

Erythromycin, a macrolide antibiotic, inhibits bacterial protein synthesis, effective against Streptococcus and Staphylococcus, and affects CYP3A4 metabolism.

Formula: C₄₉H₈₉NO₂₅

Colore e forma: Solid

Peso molecolare: 1092.233

Ref: TM-T37433

Erythromycin Lactobionate

Prodotto controllato

CAS: 3847-29-8

Applications Erythromycin Lactobionate is an antibiotic used to reduce the prevalence of drug resistant bacteria as well as keeping constant the efficacy of other antibacterial drugs.
References Kiso, S. et al.: Anticanc. Res., 20, 2827 (2000); Broad, J. et al.: Brit. J. Pharm., 168,1859 (2013); Itoh, Z., et al.: Antimicrob. Agents Chemother., 26, 863(1984)

Formula: C₃₇H₆₇NO₁₃·C₁₂H₂₂O₁₂

Colore e forma: Neat

Peso molecolare: 1092.22

Ref: TR-E650040

Erythromycin iactobionate

CAS: 3847-29-8

Erythromycin lactobionate is a macrolide antibiotic, which is derived from the bacterium *Saccharopolyspora erythraea*. Its mode of action involves binding to the 50S subunit of the bacterial ribosome, thereby inhibiting protein synthesis and leading to the suppression of bacterial growth. This mechanism effectively targets gram-positive bacteria and some gram-negative bacteria, making it a crucial agent in the fight against various bacterial infections.

Formula: C₄₉H₈₇NO₂₄

Purezza: Min. 95%

Colore e forma: White To Off-White Solid

Peso molecolare: 1,074.21 g/mol

Ref: 3D-AE37145

Erythromycin lactobioate A

CAS: 3847-29-8

Formula: C₃₇H₆₇NO₁₃C₁₂H₂₂O₁₂

Peso molecolare: 733.94 : 358.3

Ref: ST-EA-CP-E18027