CAS 38916-34-6

somatostatina

Descrizione:

somatostatina è un ormone peptidico composto da 14 aminoacidi, noto principalmente per il suo ruolo nell'inibire la secrezione di altri ormoni, tra cui l'ormone della crescita e l'insulina. Viene prodotto in vari tessuti, in particolare nell'ipotalamo e nel tratto gastrointestinale. somatostatina funge da ormone regolatore, svolgendo un ruolo cruciale nel sistema endocrino modulando l'attività di altri ormoni e neurotrasmettitori. Il suo numero CAS, 38916-34-6, lo identifica in modo univoco nei database chimici. La sostanza è caratterizzata dalla sua vita media relativamente breve in circolazione, richiedendo un'attenta somministrazione in contesti terapeutici. Gli analoghi di somatostatina sono spesso utilizzati in contesti clinici per gestire condizioni come l'acromegalia, alcuni tipi di tumori e disturbi gastrointestinali. Il peptide mostra un alto grado di specificità nella sua azione, legandosi ai recettori di somatostatina, che sono distribuiti in tutto il corpo, influenzando vari processi fisiologici. In generale, somatostatina è un componente vitale della regolazione ormonale, con implicazioni significative sia per la salute che per la gestione delle malattie.

Formula: C₇₆H₁₀₄N₁₈O₁₉S₂

InChI: InChI=1/C76H104N18O19S2/c1-41(79)64(100)82-37-61(99)83-58-39-114-115-40-59(76(112)113)92-72(108)57(38-95)91-75(111)63(43(3)97)94-71(107)54(33-46-23-11-6-12-24-46)90-74(110)62(42(2)96)93-66(102)51(28-16-18-30-78)84-69(105)55(34-47-36-81-49-26-14-13-25-48(47)49)88-68(104)53(32-45-21-9-5-10-22-45)86-67(103)52(31-44-19-7-4-8-20-44)87-70(106)56(35-60(80)98)89-65(101)50(85-73(58)109)27-15-17-29-77/h4-14,19-26,36,41-43,50-59,62-63,81,95-97H,15-18,27-35,37-40,77-79H2,1-3H3,(H2,80,98)(H,82,100)(H,83,99)(H,84,105)(H,85,109)(H,86,103)(H,87,106)(H,88,104)(H,89,101)(H,90,110)(H,91,111)(H,92,108)(H,93,102)(H,94,107)(H,112,113)

Sinonimi:

• 1: PN: US20020156010 PAGE: 3 unclaimed protein
• 15: PN: WO2007081792 SEQID: 30 claimed protein
• 15-28-Somatostatin-28
• 243: PN: EP1170021 SEQID: 2 claimed protein
• 34: PN: WO2007058336 SEQID: 34 claimed protein
• Cyclic growth hormone release-inhibiting hormone
• Cyclic ovine somatostatin
• Cyclic somatostatin
• Cyclic somatostatin-14
• Cyclic somatotropin release-inhibitor factor
• Cyclic tetradecapeptide somatostatin
• Lampetra fluviatilis somatostatin-14
• Somatostatin
• Somatostatin (Amphiuma tridactylum)
• Somatostatin (Anguilla anguilla)
• Somatostatin (Gopherus agassizii)
• Somatostatin (human)
• Somatostatin (Lophius americanus)
• Somatostatin (Myxine glutinosa)
• Somatostatin (pigeon)
• Somatostatin (rat)
• Somatostatin (sheep reduced), cyclic (3→14)-disulfide
• Somatostatin I (Lophius americanus)
• Somatostatin SS-14
• Somatostatin-14 (Gopherus agassizii)
• Somatostatin-14 (sheep)
• Somatostatina
• Somatostatine
• Sr 9357
• Sst 14
• Stilamin
• Synthetic cyclic growth hormone release-inhibiting factor
• Synthetic cyclic growth hormone release-inhibiting hormone
• Synthetic growth hormone release-inhibiting hormone
• Synthetic somatostatin-14
• Somatostatin 14
• Somatostatin Acetate
• somatostatin gamma-irradiated*cell culture tested
• H-Ala-Gly-Cys-Lys-Asn-Phe-Phe-Trp-Lys-Thr-Phe-Thr-Ser-Cys-OH (Disulfide bond)
• alanyl-N-[19,34-bis(4-aminobutyl)-31-(2-amino-2-oxoethyl)-13,25,28-tribenzyl-4-carboxy-10,16-bis(1-hydroxyethyl)-7-(hydroxymethyl)-22-(1H-indol-3-ylmethyl)-6,9,12,15,18,21,24,27,30,33,36-undecaoxo-1,2-dithia-5,8,11,14,17,20,23,26,29,32,35-undecaazacyclooctatriacontan-37-yl]glycinamide

Somatostatin 14

CAS: 38916-34-6

For cellular and molecular biology applications

Formula: C₇₆H₁₀₄N₁₈O₁₉S₂

Peso molecolare: 1637.89

Ref: 02-J66168

Somatostatin-14

CAS: 38916-34-6

Somatostatin-14 (SRIF) was originally isolated from ovine hypothalamic extracts on the basis of its ability to inhibit the secretion of radioimmunoassayable growth hormone by primary cultures of enzymatically dispersed rat anterior pituitary cells. SRIF is a small cyclic neuropeptide hormone with broad inhibitory effects on endocrine secretions such as the production of GH, glucagon, and insulin.

Formula: C₇₆H₁₀₄N₁₈O₁₉S₂

Purezza: 99.7%

Colore e forma: White Powder

Peso molecolare: 1637.9

Ref: 01-4033009

SOMATOSTATIN CRS

CAS: 38916-34-6

SOMATOSTATIN CRS

Formula: C₇₆H₁₀₄N₁₈O₁₉S₂

Peso molecolare: 1637.878

Ref: 41-S0945000

Somatostatin acetate

CAS: 38916-34-6

Formula: C₇₆H₁₀₄N₁₈O₁₉S₂

Peso molecolare: 1637.89

Ref: 7W-GM7474

Somatostatin Diacetate

CAS: 38916-34-6

Formula: C₇₆H₁₀₄N₁₈O₁₉S₂·2C₂H₄O₂

Peso molecolare: 1637.90 2*60.05

Ref: 4Z-PS-219001

Somatostatin Acetate

CAS: 38916-34-6

Formula: C₇₆H₁₀₄N₁₈O₁₉S₂

Purezza: 95%~99%

Colore e forma: White to Off-white Powder

Peso molecolare: 1637.88

Ref: BP-BPPG058

Somatostatin Acetate

CAS: 38916-34-6

Applications Growth hormone-release inhibiting factor; treatment of severe, acute hemorrhage of gastroduodenal ulcers; experimental antidiabetic.
References Brazeau, P., et al.: Science, 179, 77 (1973), Siler, T.M., et al.: J. Clin. Endocrinol. Metab., 37, 632 (1973), Pradayrol, L., et al.: Biochem. Biophys. Res. Commun., 85, 701 (1978), Mandarino, L., et al.: Nature, 291, 76 (1981),

Formula: C₇₈H₁₀₈N₁₈O₂₁S₂

Colore e forma: Neat

Peso molecolare: 1697.93

Ref: TR-S676750

Cyclic somatostatin

CAS: 38916-34-6

Cyclic somatostatin (SRIF-14) is a cyclic tetradecapeptide regulating many endocrine and nervous system functions.

Formula: C₇₆H₁₀₄N₁₈O₁₉S₂

Purezza: 96.86%

Colore e forma: Powder

Peso molecolare: 1637.88

Ref: TM-TP1035

Somatostatin extrapure, 97%

CAS: 38916-34-6

Formula: C₇₆H₁₀₄N₁₈O₁₉S₂

Purezza: min. 97%

Colore e forma: White to off-white, Powder

Peso molecolare: 1637.88

Ref: SR-54281

Somatostatin (Human, Ovine, Porcine, Rat, Mouse)

CAS: 38916-34-6

Somatostatin is a peptide hormone that has been found to inhibit pituitary growth hormone release as well as endocrine, pancreatic and GI secretions. It is widely expressed throughout the body for example in the gastrointestinal (GI) tract, hypothalamus, pancreas and the central nervous system. In the central nervous system somatostatin plays a role in neurotransmission modification and it has also demonstrated to be effective against a number of cancers such as squamous carcinoma. This product contains disulfide bonds between Cys3-Cys14 and is available as a 0.5mg vial.

Formula: C₇₆H₁₀N₁₈O₁₉S₂

Purezza: Min. 95%

Peso molecolare: 1,637.9 g/mol

Ref: 3D-PSI-4023-V

Somatostatin

CAS: 38916-34-6

Somatostatin is a peptide hormone that is produced by the hypothalamus and inhibits the release of growth hormones, stimulates the release of insulin from the pancreas, and inhibits the release of glucagon from the pancreas. Somatostatin also has biological properties that inhibit neuronal death in combination therapy groups. It has been shown to have cell factor activity which may contribute to its antitumor activity. Somatostatin also has pro-apoptotic properties in vitro assays at physiological levels, making it an excellent target for cancer therapy.

Formula: C₇₆H₁₀₄N₁₈O₁₉S₂

Purezza: Min. 95%

Peso molecolare: 1,637.9 g/mol

Ref: 3D-HOR-299

Somatostatin

CAS: 38916-34-6

Somatostatin is a polypeptide hormone that is produced by the body to inhibit the release of other hormones in the body. It has also been used to treat diseases such as carcinoid syndrome, intestinal disorders, and diabetes mellitus type I. Somatostatin binds to somatostatin receptors on cells, which leads to inhibition of cell growth and secretion of hormones. Somatostatin has been shown to block basic protein synthesis and energy metabolism in rat liver cells. Its receptor activity is mediated by binding with signal peptide sequences and response elements.

Formula: C₇₆H₁₀₄N₁₈O₁₉S₂

Purezza: Min. 95%

Colore e forma: Powder

Peso molecolare: 1,637.88 g/mol

Ref: 3D-FS27855

Cyclic Somatostatin

CAS: 38916-34-6

Formula: C₇₆H₁₀₄N₁₈O₁₉S₂

Purezza: 97%

Colore e forma: Liquid

Peso molecolare: 1637.8781599999995

Ref: IN-DA00IMLT