CAS 39178-35-3

Cloruro di isonicotinile cloridrato

Descrizione:

Cloruro di isonicotinile cloridrato è un composto chimico che appartiene alla classe dei cloruri acilici, specificamente derivato dall'acido isonicotinico. È caratterizzato dalla sua reattività dovuta alla presenza del gruppo funzionale cloruro acilico, che lo rende un intermedio utile nella sintesi organica, in particolare nella preparazione di vari farmaci e agrochimici. Il composto appare tipicamente come un solido bianco a bianco sporco ed è solubile in solventi organici polari. È importante maneggiare Cloruro di isonicotinile cloridrato con cura, poiché può essere corrosivo e può rilasciare acido cloridrico durante l'idrolisi. Il composto è spesso utilizzato nella sintesi di derivati isonicotinoyl, che hanno applicazioni in chimica medicinale, in particolare nello sviluppo di agenti anti-tubercolosi e altri composti terapeutici. Devono essere osservate precauzioni di sicurezza quando si lavora con questa sostanza, incluso l'uso di adeguati dispositivi di protezione individuale e lavorare in un'area ben ventilata o in una cappa.

Formula: C₆H₄ClNO·ClH

InChI: InChI=1S/C6H4ClNO.ClH/c7-6(9)5-1-3-8-4-2-5;/h1-4H;1H

InChI key: InChIKey=BNTRVUUJBGBGLZ-UHFFFAOYSA-N

SMILES: C(Cl)(=O)C=1C=CN=CC1.Cl

Sinonimi:

• (Chlorocarbonyl)-4-(pyridinyl) monohydrochloride
• 4-(Chloroformyl)pyridinium hydrochloride
• 4-Nicotinoyl chloride hydrochloride
• 4-Pyridinecarbonyl chloride, hydrochloride
• 4-Pyridinecarbonyl chloride, hydrochloride (1:1)
• 4-Pyridinecarboxylic acid chloride hydrochloride
• 4-Pyridinoyl Chloride Hydrochloride
• Isonicotinic acid chloride hydrochloride
• Isonicotinoyl Chloride Hydrochloride
• Isonicotinoyl Chloride Hydrochloride, 95 %
• Isonicotinoyl Chloride Hydrochloride,Pyridine-4-Carbonyl Chloride
• IsonicotinoylchlorideHCl
• Isonicotinyl Chloride Hydrochloride
• Pyridine-4-Carbonyl Chloride Hydrochloride
• Pyridine-4-Carbonyl Chloride Hydrochloride (1:1)
• Pyridine-4-carbonylchlorideHCl
• Timtec-Bb Sbb003768

Isonicotinoyl chloride hydrochloride, 97%

CAS: 39178-35-3

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Sci

Formula: C₆H₅Cl₂NO

Purezza: 97%

Colore e forma: White to cream to pale brown or pale yellow, Crystalline powder

Peso molecolare: 178.01

Ref: 02-A10863

Isonicotinoyl chloride hydrochloride

CAS: 39178-35-3

Formula: C₆H₅Cl₂NO

Purezza: 95%

Colore e forma: Solid

Peso molecolare: 178.0160

Ref: IN-DA003R41

Isonicotinoyl Chloride Hydrochloride

CAS: 39178-35-3

Formula: C₆H₄ClNO·HCl

Purezza: >95.0%(T)

Colore e forma: White to Almost white powder to crystal

Peso molecolare: 178.01

Ref: 3B-I0144

Isonicotinoyl chloride hydrochloride

CAS: 39178-35-3

Isonicotinoyl chloride hydrochloride

Formula: C₆H₄ClNO·ClH

Purezza: 95%

Colore e forma: white powder

Peso molecolare: 178.02g/mol

Ref: 54-OR23065

Isonicotinoyl chloride hydrochloride

CAS: 39178-35-3

Isonicotinoyl chloride HCl is a macrocyclic inhibitor of the nuclear hormone receptor (NR) that belongs to the class of organic compounds. It is used in the treatment of inflammatory diseases and infectious diseases. Isonicotinoyl chloride HCl has been shown to inhibit nitric oxide synthase, which leads to an inhibition of inflammatory reactions in various tissues. This compound also inhibits p. aeruginosa and alkylthio group, which may be due to its coordination geometry or aromatic hydrocarbon. Isonicotinoyl chloride HCl binds to mineralocorticoid receptors on cells and blocks their transcriptional activity, thereby inhibiting inflammation and oxidative stress.

Formula: C₆H₄ClNO•HCl

Purezza: Min. 95%

Colore e forma: White To Beige Solid

Peso molecolare: 178.02 g/mol

Ref: 3D-FI29482

Isonicotinoyl chloride hydrochloride

CAS: 39178-35-3

Formula: C₆H₅Cl₂NO

Purezza: 95%

Colore e forma: Solid, White to almost white powder

Peso molecolare: 178.01

Ref: 10-F066672

Isonicotinyl Chloride Hydrochloride

Prodotto controllato

CAS: 39178-35-3

Stability Sensitive to moisture
Applications Isonicotinyl Chloride Hydrochloride, is a heterocyclic building block used for the synthesis of various pharmaceutical and biologically active compounds. It can be used for the preparation of Tetrahydropyrroloquinolinone type dual inhibitors of Aromatase/Aldosterone Synthase, as a novel stagey for breast cancer patients with the risk of cardiovascular diseases.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Yin, L., et al.: J. Med. Chem., 56 (2), 460 (2013);

Formula: C₆H₅Cl₂NO

Colore e forma: Neat

Peso molecolare: 178.02

Ref: TR-I821755