CAS 392711-19-2

Rapamycin-d3 (Sirolimus-d3)

CAS: 392711-19-2

Formula: C₅₁H₇₆D₃NO₁₃

Colore e forma: White To Off-White Solid

Peso molecolare: 917.21

Ref: 4Z-R-181

Rapamycin-d3

CAS: 392711-19-2

Rapamycin-d3 is the deuterium labeled Rapamycin. Rapamycin is a potent and specific inhibitor of mTOR(IC50 of 0.1 nM in HEK293 cells).

Formula: C₅₁H₇₉NO₁₃

Purezza: 98%

Colore e forma: Solid

Peso molecolare: 917.19

Ref: TM-T12691

Rapamycin-d3 (contains d0) Technical Grade

Prodotto controllato

CAS: 392711-19-2

Stability Moisture Sensitive
Applications Labelled Rapamycin. A triene macrolide antibiotic isolated from Streptomyces hygroscopicus. Name derived from the native word for Easter Island, Rapa’Nui. Used as an immunosuppressant; antirestenotic.This compound contains aproximately 2% d0.
References Martel, P.R., et al.: Can. J. Physiol. Pharmacol., 55, 48 (1977), Carlson, R.P., et al.: J. Pharmacol. Exp. Ther., 266, 1125 (1993), Kahan, B.D., et al.: Lancet, 356, 194 (2000), Holmes, D.R., et al.: Circulation, 109, 634 (2004),

Formula: C₅₁₂H₃H₇₆NO₁₃

Colore e forma: White

Peso molecolare: 917.19

Ref: TR-R124002

Rapamycin-d3

CAS: 392711-19-2

Rapamycin-d3 is a drug used to suppress the immune system. It is an immunosuppressant that binds to proteins in the cell and prevents them from functioning. Rapamycin-d3 has been shown to be effective in preventing rejection of transplanted organs as well as treating autoimmune disorders, such as inflammatory bowel disease (IBD). The analysis of this compound can be done using LC-MS/MS methods. In order to optimize the assay, it was necessary to perform a series of validation studies. This included determining crossreactivity with other drugs, developing a method for patient samples, and determining if there was any correlation between treatment response and patient age or sex.

Formula: C₅₁H₇₉NO₁₃

Purezza: Min. 95%

Peso molecolare: 917.2 g/mol

Ref: 3D-SQA71119

Rapamycin-d3 (contains d0) Technical Grade

CAS: 392711-19-2

Formula: C₅₁H₇₆D₃NO₁₃

Purezza: ≥98% deuterated forms (d1-d3)，1mg/ml in ethanol

Colore e forma: Solid

Peso molecolare: 917.1903

Ref: IN-DA00C811