CAS 39562-70-4

Nitrendipina

Descrizione:

Nitrendipina è un bloccante dei canali del calcio utilizzato principalmente nel trattamento dell'ipertensione e dell'angina pectoris. Appartiene alla classe dei composti diidropiridinici, caratterizzati dalla loro capacità di inibire selettivamente l'afflusso di calcio attraverso i canali del calcio di tipo L nel muscolo liscio vascolare e nel tessuto cardiaco. Questa azione porta a vasodilatazione e a una successiva diminuzione della pressione sanguigna. Nitrendipina è noto per la sua elevata lipofilia, che ne migliora l'assorbimento e la distribuzione nel corpo. Il composto presenta generalmente una lunga emivita, consentendo una somministrazione una volta al giorno in contesti clinici. La sua struttura chimica include un gruppo nitro, che contribuisce alle sue proprietà farmacologiche. Nitrendipina è generalmente ben tollerato, ma come altri bloccanti dei canali del calcio, può causare effetti collaterali come mal di testa, arrossamento o edema periferico. Come per qualsiasi farmaco, è importante considerare le controindicazioni e le potenziali interazioni con altri farmaci. In generale, Nitrendipina è un agente efficace nella gestione delle condizioni cardiovascolari, contribuendo a migliorare i risultati per i pazienti.

Formula: C₁₈H₂₀N₂O₆

InChI: InChI=1/C18H20N2O6/c1-5-26-18(22)15-11(3)19-10(2)14(17(21)25-4)16(15)12-7-6-8-13(9-12)20(23)24/h6-9,15-16H,5H2,1-4H3/t15?,16-/m1/s1

InChI key: InChIKey=PVHUJELLJLJGLN-UHFFFAOYSA-N

SMILES: C(OCC)(=O)C=1C(C(C(OC)=O)=C(C)NC1C)C2=CC(N(=O)=O)=CC=C2

Sinonimi:

• (.+-.)-Bay E 5009
• (.+-.)-Nitrendipine
• 3,5-Pyridinedicarboxylic acid, 1,4-dihydro-2,6-dimethyl-4-(3-nitrophenyl)-, 3-ethyl 5-methyl ester
• Baylotensin
• Bayotensin
• Baypress
• Bylotensin
• Cardif
• Deiten
• Nidrel
• Nitrendipin
• Nitrendipino
• Nitrepin
• 3,5-Pyridinedicarboxylic acid, 1,4-dihydro-2,6-dimethyl-4-(3-nitrophenyl)-, ethyl methyl ester
• 3-ethyl 5-methyl (4S)-2,6-dimethyl-4-(3-nitrophenyl)-3,4-dihydropyridine-3,5-dicarboxylate
• 1,4-dihydro-2,6-dimethyl-4-(3-nitrophenyl)-3,5-pyridinedicarboxylic acid ethyl methyl ester
• 3-ethyl 5-methyl (4R)-2,6-dimethyl-4-(3-nitrophenyl)-3,4-dihydropyridine-3,5-dicarboxylate
• ethyl methyl 1,4-dihydro-2,6-dimethyl-4-(meta-nitrophenyl)-3,5-pyridinedicarboxylate
• NITRENDIPINE IMPURITY AETHYL METHYL-2,6-DIMETHYL-4-(3-NITROPHENYL) PYRIDINE-3,5-DICARBOXYLATE
• ylmethylester
• NITRENDIPINE EPN(CRM STANDARD)
• (NITROPHENYLPYRIDINE ANALOGUE) EPN(CRM STANDARD)
• 3,5-Pyridinedicarboxylic acid, 1,4-dihydro-2,6-dimethyl-4-(3-nitrophenyl)-, ethyl methyl ester (9CI)
• NITRENDIPINE >95% CA2+ CHANNEL BLOCKER,
• ethylmethyl1,4-dihydro-2,6-dimethyl-4-(m-nitrophenyl)-3,5-pyridinedicarboxy
• 1,4-dihydro-2,6-dimethyl-4-(3-nitrophenyl)-3,5-pyridinedicarboxylicacidethy
• NITRENDIPINE MM(CRM STANDARD)
• baye5009

Nitrendipine

CAS: 39562-70-4

Formula: C₁₈H₂₀N₂O₆

Purezza: >98.0%(HPLC)(N)

Colore e forma: White to Yellow to Green powder to crystal

Peso molecolare: 360.37

Ref: 3B-N1186

Nitrendipine

CAS: 39562-70-4

L-type calcium channel blocker

Formula: C₁₈H₂₀N₂O₆

Colore e forma: Powder

Peso molecolare: 360.37

Ref: 02-J60841

Nitrendipine

CAS: 39562-70-4

Colore e forma: Neat

Ref: 61-FOR0092.00

NITRENDIPINE FOR PEAK IDENTIFICATION CRS

CAS: 39562-70-4

NITRENDIPINE FOR PEAK IDENTIFICATION CRS

Formula: C₁₈H₂₀N₂O₆

Peso molecolare: 360.3612

Ref: 41-Y0001456

NITRENDIPINE CRS

CAS: 39562-70-4

NITRENDIPINE CRS

Formula: C₁₈H₂₀N₂O₆

Peso molecolare: 360.3612

Ref: 41-N0905000

Nitrendipine

CAS: 39562-70-4

Formula: C₁₈H₂₀N₂O₆

Purezza: 98%

Colore e forma: Solid

Peso molecolare: 360.3612

Ref: IN-DA003T4X

Nitrendipine

CAS: 39562-70-4

Nitrendipine is a vasodilating calcium channel blocker and antihypertensive that preserves kidney function and promotes sodium excretion.

Formula: C₁₈H₂₀N₂O₆

Purezza: 99% - 99.55%

Colore e forma: Solid

Peso molecolare: 360.36

Ref: TM-T0119

Nitrendipine

CAS: 39562-70-4

Nitrendipine

Purezza: ≥98%

Peso molecolare: 360.36g/mol

Ref: 54-BUP15672

Lercanidipine EP Impurity B

CAS: 39562-70-4

Formula: C₁₈H₂₀N₂O₆

Colore e forma: Yellow Solid

Peso molecolare: 360.37

Ref: 4Z-L-1714

Nitrendipine

CAS: 39562-70-4

Nitrendipine

Purezza: 98%

Peso molecolare: 360.36g/mol

Ref: 54-OR1030253

Nitrendipine

CAS: 39562-70-4

Formula: C₁₈H₂₀N₂O₆

Peso molecolare: 360.37

Ref: 4Z-N-060002

Nitrendipine

CAS: 39562-70-4

Formula: C₁₈H₂₀N₂O₆

Purezza: ≥ 97.0%

Colore e forma: Pale yellow to yellow or green powder

Peso molecolare: 360.36

Ref: 7W-GP6940

NITRENDIPINE

CAS: 39562-70-4

Purezza: 95+%

Peso molecolare: 360.3659973

Ref: 10-F813117

Nitrendipine 100 µg/mL in Acetonitrile

CAS: 39562-70-4

Formula: C₁₈H₂₀N₂O₆

Colore e forma: Single Solution

Peso molecolare: 360.36

Ref: 04-A15529500AL-100

Nitrendipine

Prodotto controllato

CAS: 39562-70-4

Formula: C₁₈H₂₀N₂O₆

Colore e forma: Neat

Peso molecolare: 360.36

Ref: 04-C15529500

Nitrendipine

Prodotto controllato

CAS: 39562-70-4

Formula: C₁₈H₂₀N₂O₆

Colore e forma: Neat

Peso molecolare: 360.36

Ref: 86-MM0092.00

Nitrendipine

Prodotto controllato

CAS: 39562-70-4

Applications Nitrendipine is a dihydropyridine calcium channel blocker. Nitrendipine is used in the treatment of primary (essential) hypertension to decrease blood pressure. Antihypertensive.
References Ventura, H.O., et al.: Am. J. Cardiol., 51, 783 (1983); Kann, J. et al.: Brit. J. Clin. Pharmacol., 33, 51 (1992);

Formula: C₁₈H₂₀N₂O₆

Colore e forma: Neat

Peso molecolare: 360.36

Ref: TR-N490150

Nitrendipine-d5

Prodotto controllato

CAS: 39562-70-4

Applications Nitrendipine-d5 is the isotope labelled analogue of Nitrendipine (N490150), a dihydropyridine calcium channel blocker. Nitrendipine is used in the treatment of primary (essential) hypertension to decrease blood pressure. Antihypertensive.
References Ventura, H.O., et al.: Am. J. Cardiol., 51, 783 (1983),

Formula: C₁₈H₁₅D₅N₂O₆

Colore e forma: Neat

Peso molecolare: 365.39

Ref: TR-N490152

(RS)-Methyl ethyl 1,4-dihydro-2,6-dimethyl-4-(3-nitrophenyl)pyridine-3,5-dicarboxylate

CAS: 39562-70-4

Methyl ethyl 1,4-dihydro-2,6-dimethyl-4-(3-nitrophenyl)pyridine-3,5-dicarboxylate is a propranolol hydrochloride derivative that has vasodilatory effects. It is used as a nitrovasodilator to treat angina pectoris and high blood pressure. Methyl ethyl 1,4-dihydro-2,6-dimethyl-4-(3-nitrophenyl)pyridine-3,5-dicarboxylate binds to the alpha1 adrenergic receptors in the heart and causes vasodilation by inhibiting the release of norepinephrine from sympathetic nerves. This drug also inhibits the binding of norepinephrine to cardiac beta receptors which decreases the heart rate and contractility of cardiac muscle. Methyl ethyl 1,4-dihydro-2,6

Formula: C₁₈H₂₀N₂O₆

Purezza: Min. 95%

Colore e forma: Yellow Powder

Peso molecolare: 360.36 g/mol

Ref: 3D-IM57947

(RS)-Methyl ethyl 1,4-dihydro-2,6-dimethyl-4-(3-nitrophenyl)pyridine-3,5-dicarboxylate - EP Grade

CAS: 39562-70-4

Propranolol hydrochloride is a non-selective beta-adrenergic blocker that blocks the effects of epinephrine, norepinephrine and dopamine. Propranolol hydrochloride has been shown to inhibit the activity of proximal tubules in the kidney, which may be due to its inhibition of chemical ionization. This drug also has antihypertensive activity and can be used for the treatment of cardiac disorders such as hypertension. Propranolol hydrochloride is a monoclonal antibody that is activated by nitro groups and binds with high affinity to multiple-reaction monitoring (MRM) transitions for protonated molecular ions at m/z 289, 296, 305, 313, 320, 328, 336 and 344. Propranolol hydrochloride also has vasodilatory effects on the papillary muscle which aids in regulating blood pressure by maintaining vascular resistance.

Formula: C₁₈H₂₀N₂O₆

Purezza: Min. 95%

Peso molecolare: 360.36 g/mol

Ref: 3D-IM175687