CAS 39831-55-5

Solfato di amikacina

Descrizione:

Solfato di amikacina è un antibiotico aminoglicosidico utilizzato principalmente per trattare infezioni gravi causate da batteri Gram-negativi, in particolare nei casi in cui altri antibiotici possono essere inefficaci. È un derivato semisintetico della kanamicina e presenta un ampio spettro di attività antibatterica. La struttura chimica di Solfato di amikacina include un gruppo amminico che ne migliora l'efficacia contro ceppi resistenti. Viene tipicamente somministrato per iniezione ed è noto per la sua tossicità relativamente bassa rispetto ad altri aminoglicosidi, sebbene possa comunque causare nefrotossicità e ototossicità. La sostanza è solubile in acqua, il che facilita il suo utilizzo in contesti clinici. Solfato di amikacina è spesso usato in combinazione con altri antibiotici per migliorare i risultati terapeutici, specialmente in infezioni gravi come quelle causate da Pseudomonas aeruginosa. La sua farmacocinetica prevede l'escrezione renale, richiedendo aggiustamenti del dosaggio nei pazienti con funzione renale compromessa. In generale, Solfato di amikacina rimane un'opzione critica nell'arsenale degli antibiotici, particolarmente per infezioni multiresistenti.

Formula: C₂₂H₄₇N₅O₂₁S₂

InChI: InChI=1/C22H43N5O13.H2O4S/c23-2-1-8(29)20(36)27-7-3-6(25)18(39-22-16(34)15(33)13(31)9(4-24)37-22)17(35)19(7)40-21-14(32)11(26)12(30)10(5-28)38-21;1-5(2,3)4/h6-19,21-22,28-35H,1-5,23-26H2,(H,27,36);(H2,1,2,3,4)/t6-,7+,8-,9+,10+,11-,12+,13+,14+,15-,16+,17-,18+,19-,21+,22+;/m0./s1

InChI key: InChIKey=HIBICIOPDUTNRR-XTHCGPPUSA-N

SMILES: O([C@H]1[C@H](NC([C@H](CCN)O)=O)C[C@H](N)[C@@H](O[C@H]2O[C@H](CN)[C@@H](O)[C@H](O)[C@H]2O)[C@@H]1O)[C@H]3O[C@H](CO)[C@@H](O)[C@H](N)[C@H]3O.S(=O)(=O)(O)O

Sinonimi:

• (2R)-4-amino-N-{(1R,2S,3S,4R,5S)-5-amino-2-[(3-amino-3-deoxy-α-D-glucopyranosyl)oxy]-4-[(6-amino-6-deoxy-α-D-glucopyranosyl)oxy]-3-hydroxycyclohexyl}-2-hydroxybutanamide sulfate (salt)
• (2S)-4-amino-N-{(1R,2S,3S,4R,5S)-5-amino-2-[(3-amino-3-deoxy-alpha-D-glucopyranosyl)oxy]-4-[(6-amino-6-deoxy-alpha-D-glucopyranosyl)oxy]-3-hydroxycyclohexyl}-2-hydroxybutanamide sulfate (1:2)
• (2S)-4-amino-N-{(1R,2S,3S,4R,5S)-5-amino-2-[(3-amino-3-deoxy-alpha-D-glucopyranosyl)oxy]-4-[(6-amino-6-deoxy-alpha-D-glucopyranosyl)oxy]-3-hydroxycyclohexyl}-2-hydroxybutanamide sulfate (salt)
• 4-Amino-N-[5-Amino-2-[4-Amino-3,5-Dihydroxy-6-(Hydroxymethyl)Tetrahydropyran-2-Yl]Oxy-4-[6-(Aminomethyl)-3,4,5-Trihydroxy-Tetrahydropyran-2-Yl]Oxy-3-Hydroxy-Cyclohexyl]-2-Hydroxy-Butanamide Disulfate Salt
• 8-chloro-1,3-dimethyl-3,7-dihydro-1H-purine-2,6-dione - 2-(diphenylmethoxy)-N,N-dimethylethanamine (1:1)
• <span class="text-smallcaps">D</smallcap>-Streptamine, O-3-amino-3-deoxy-α-<smallcap>D</smallcap>-glucopyranosyl-(1→6)-O-[6-amino-6-deoxy-α-<smallcap>D</span>-glucopyranosyl-(1→4)]-N¹-(4-amino-2-hydroxy-1-oxobutyl)-2-deoxy-, (S)-, sulfate (1:2) (salt)
• <span class="text-smallcaps">D</smallcap>-Streptamine, O-3-amino-3-deoxy-α-<smallcap>D</smallcap>-glucopyranosyl-(1→6)-O-[6-amino-6-deoxy-α-<smallcap>D</span>-glucopyranosyl-(1→4)]-N¹-[(2S)-4-amino-2-hydroxy-1-oxobutyl]-2-deoxy-, sulfate (1:2)
• <span class="text-smallcaps">D</smallcap>-Streptamine, O-3-amino-3-deoxy-α-<smallcap>D</smallcap>-glucopyranosyl-(1→6)-O-[6-amino-6-deoxy-α-<smallcap>D</span>-glucopyranosyl-(1→4)]-N¹-[(2S)-4-amino-2-hydroxy-1-oxobutyl]-2-deoxy-, sulfate (1:2) (salt)
• Amiglyde V
• Amika
• Amikacin Disulfate Salt
• Amikacin Sulfate
• Amikacin Sulfate 1:1.8
• Amikacin Sulfate Salt
• Amikacin disulfate
• Amikavet
• Amikin
• Amiklin
• Antibiotic BB-K 8 sulfate
• Arikayce liposomal
• Biklin
• Biodacyn
• Biodacyna
• Fabianol
• Grasil
• Kaminax
• Mikavir
• Novamin
• Pierami
• Selemycin
• D-Streptamine, O-3-amino-3-deoxy-α-D-glucopyranosyl-(1→6)-O-[6-amino-6-deoxy-α-D-glucopyranosyl-(1→4)]-N1-(4-amino-2-hydroxy-1-oxobutyl)-2-deoxy-, (S)-, sulfate (1:2) (salt)
• D-Streptamine, O-3-amino-3-deoxy-α-D-glucopyranosyl-(1→6)-O-[6-amino-6-deoxy-α-D-glucopyranosyl-(1→4)]-N1-[(2S)-4-amino-2-hydroxy-1-oxobutyl]-2-deoxy-, sulfate (1:2) (salt)
• D-Streptamine, O-3-amino-3-deoxy-α-D-glucopyranosyl-(1→6)-O-[6-amino-6-deoxy-α-D-glucopyranosyl-(1→4)]-N1-[(2S)-4-amino-2-hydroxy-1-oxobutyl]-2-deoxy-, sulfate (1:2)
• antibioticbb-k8sulfate
• (s)-ysulfate(1:2)(salt)
• AMIKACIN SULFATE, PHARMA
• AmikacinSulphateNon-Sterial
• AMIKACINSULFATE,USP
• AMIKACIN SULFATE 1:2
• AMIKACIN SULFATE USP JP
• Amikacin Sulfate(Sterile)
• Amikacin Sulfate(Non-Sterile)
• Sterile
• AMIKACIN SULPHATE
• y-alpha-d-glucopyranosyl-(1-4))-n(sup1)-(4-amino-2-hydroxy-1-oxobutyl)-2-deox
• amikacin bis(sulphate)

Amikacin Sulfate

CAS: 39831-55-5

Formula: C₂₂H₄₃N₅O₁₃·2H₂SO₄

Purezza: >98.0%(HPLC)

Colore e forma: White to Light yellow powder to crystal

Peso molecolare: 781.75

Ref: 3B-A2281

Amikacin disulfate

CAS: 39831-55-5

An aminoglycoside antibiotic derived from Kanamycin A

Formula: C₂₂H₄₃N₅O₁₃•2H₂SO₄

Peso molecolare: 781.77

Ref: 02-J63862

Amikacin sulfate

CAS: 39831-55-5

Amikacin sulfate

Formula: C₂₂H₄₃N₅O₁₃H₂SO₄

Purezza: 89.0%

Colore e forma: White To Off-White

Peso molecolare: 683.25312

Ref: 47-853

AMIKACIN SULFATE CRS

CAS: 39831-55-5

AMIKACIN SULFATE CRS

Formula: C₂₂H₄₅N₅O₁₇S

Peso molecolare: 683.681

Ref: 41-A0365900

Amikacin Sulfate

CAS: 39831-55-5

Antibiotics nesoi

Formula: C₂₂H₄₃N₅O₁₃·2H₂SO₄

Colore e forma: White Powder

Peso molecolare: 585.28574

Ref: 45-1019494

Amikacin Sulfate

CAS: 39831-55-5

Formula: C₂₂H₄₇N₅O₂₁S₂

Purezza: 97%

Colore e forma: Solid

Peso molecolare: 781.7595

Ref: IN-DA00I7TF

Amikacin disulfate salt

CAS: 39831-55-5

Formula: C₂₂H₄₃N₅O₁₃·2H₂SO₄

Purezza: 674 - 786 μg/mg (anhydrous basis, 1:2)

Colore e forma: White to off-white powder

Peso molecolare: 781.77

Ref: 7W-GA2441

Amikacin disulphate salt

CAS: 39831-55-5

Amikacin disulphate salt

Formula: C₂₂H₄₃N₅O₁₃·2H₂SO₄

Colore e forma: crystalline powder

Peso molecolare: 781.76g/mol

Ref: 54-BIA1010

Amikacin disulfate

CAS: 39831-55-5

Amikacin disulfate

Purezza: ≥98%

Peso molecolare: 781.76g/mol

Ref: 54-BUP18672

Amikacin Sulfate

CAS: 39831-55-5

Colore e forma: Neat

Ref: 86-MM1279.00

Amikacin disulfate

CAS: 39831-55-5

Amikacin disulfate (BAY-416651 sulfate) is a semi-synthetic aminoglycoside antibiotic derived from kanamycin A.

Formula: C₂₂H₄₃N₅O₁₃·2H₂O₄S

Purezza: 98.67% - 99.3%

Colore e forma: White Crystalline Powder From Methanol-Isopropanol Solid

Peso molecolare: 781.76

Ref: TM-T6382

Amikacin Sulfate

Prodotto controllato

CAS: 39831-55-5

Stability Hygroscopic
Applications Semisynthetic aminoglycoside antibiotic derived from Kanamycin A. Antibacterial.
References Cabana, T., et al.: Antimicrob. Agents Chemother., 3, 478 (1973), Cappelletti, L.M., et al.: J. Antibiot., 36, 328 (1983), Monteleone, P.M., et al.: Anal. Profiles Drug Subs., 12, 37 (1983),

Formula: C₂₂H₄₃N₅O₁₃·2H₂O₄S

Colore e forma: White To Off-White

Peso molecolare: 781.76

Ref: TR-A578500

Amikacin Disulfate

CAS: 39831-55-5

Formula: C₂₂H₄₃N₅O₁₃(H₂SO₄)

Peso molecolare: 585.6 : 2(98.1)

Ref: ST-EA-CP-A190010

Amikacin disulfate

CAS: 39831-55-5

Inhibitor of protein synthesis; aminoglycoside

Formula: C₂₂H₄₃N₅O₁₃·2H₂SO₄

Purezza: 674 To 786 Usp U/Mg

Colore e forma: White Powder

Peso molecolare: 781.76 g/mol

Ref: 3D-AA17356

Amikacin Sulphate (AMKS)

CAS: 39831-55-5

Formula: C₂₂H₄₃N₅O₁₃·2H₂SO₄

Colore e forma: White, Crystalline powder

Peso molecolare: 781.75

Ref: SR-18036

Amikacin sulfate salt (contains 10% H2O)

CAS: 39831-55-5

Formula: C₂₂H₄₇N₅O₂₁S₂

Purezza: 95.0%

Colore e forma: Solid, White powder

Peso molecolare: 781.75

Ref: 10-F361958

Amikacin-d5 Sulfate

Prodotto controllato

CAS: 39831-55-5

Formula: C₂₂H₄₂D₅N₅O₂₁S₂

Colore e forma: Neat

Peso molecolare: 786.78

Ref: TR-A578502