CAS 402-49-3

4-(Trifluorometil)bromuro di benzile

Descrizione:

4-(Trifluorometil)bromuro di benzile è un composto organico caratterizzato dalla presenza di un gruppo bromobenzilico con un sostituente trifluorometilico nella posizione para. La sua formula molecolare è C9H7BrF3, che indica la presenza di atomi di carbonio, idrogeno, bromo e fluoro. Questo composto appare tipicamente come un liquido incolore o giallo pallido ed è noto per la sua reattività a causa della presenza dell'atomo di bromo, che può partecipare a reazioni di sostituzione nucleofila. Il gruppo trifluorometilico contribuisce alle uniche proprietà elettroniche del composto, migliorando la sua lipofilia e potenzialmente influenzando la sua attività biologica. 4-(Trifluorometil)bromuro di benzile è spesso utilizzato nella sintesi organica, in particolare nella preparazione di farmaci e agrochimici, grazie alla sua capacità di fungere da reagente elettrofilo. Devono essere adottate precauzioni di sicurezza quando si maneggia questo composto, poiché può comportare rischi per la salute attraverso l'inalazione o il contatto con la pelle. Metodi adeguati di stoccaggio e smaltimento sono essenziali per mitigare l'impatto ambientale e garantire la sicurezza negli ambienti di laboratorio.

Formula: C₈H₆BrF₃

InChI: InChI=1S/C8H6BrF3/c9-5-6-1-3-7(4-2-6)8(10,11)12/h1-4H,5H2

InChI key: InChIKey=IKSNDOVDVVPSMA-UHFFFAOYSA-N

SMILES: C(F)(F)(F)C1=CC=C(CBr)C=C1

Sinonimi:

• 1-Trifluoromethyl-4-(bromomethyl)benzene
• 4-(Trifluoromethyl)Benzyl Bromide
• 4-Bromomethylbenzotrifluoride
• 4-Trifluoromethylbenzyl Bromide
• Benzene, 1-(bromomethyl)-4-(trifluoromethyl)-
• p-(Trifluoromethyl)benzyl bromide
• p-Xylene, α′-bromo-α,α,α-trifluoro-
• α′-Bromo-α,α,α-trifluoro-p-xylene
• 1-(Bromomethyl)-4-(trifluoromethyl)benzene

4-(Trifluoromethyl)benzyl Bromide

CAS: 402-49-3

Formula: C₈H₆BrF₃

Purezza: >98.0%(GC)

Colore e forma: White or Colorless to Light yellow powder to lump to clear liquid

Peso molecolare: 239.04

Ref: 3B-T1313

4-(Trifluoromethyl)benzyl bromide, 98%

CAS: 402-49-3

4-(Trifluoromethyl)benzyl bromide can be used to produce p-trifluoromethylbenzyl phenyl sulfide. It is used in medicine. This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The

Formula: C₈H₆BrF₃

Purezza: 98%

Colore e forma: Crystals or powder or crystalline powder or fused solid, White to cream

Peso molecolare: 239.04

Ref: 02-A16895

4-(Trifluoromethyl)benzyl bromide

CAS: 402-49-3

Formula: C₈H₆BrF₃

Purezza: 98%

Colore e forma: Solid

Peso molecolare: 239.0324

Ref: IN-DA0033U8

4-(Trifluoromethyl)benzyl bromide

CAS: 402-49-3

4-(Trifluoromethyl)benzyl bromide

Formula: C₈H₆BrF₃

Purezza: 98%

Colore e forma: white to off white fused solid

Peso molecolare: 239.03g/mol

Ref: 54-PC7633

4-(Trifluoromethyl)benzyl bromide

CAS: 402-49-3

Formula: C₈H₆BrF₃

Purezza: 98.0%

Colore e forma: Low Melting Solid

Peso molecolare: 239.035

Ref: 10-F007607

4-(Trifluoromethyl)benzyl Bromide

Prodotto controllato

CAS: 402-49-3

Applications 4-(Trifluoromethyl)benzyl Bromide is a useful building block. It is used in the synthesis of 1-(Substituted benzyl)-2-substituted-5,6-dichlorobenzimidazoles with antiviral activities.It is also used to prepare 2-[(4-diarylmethoxy)phenyl]benzimidazoles as potent inhibitors of hepatitis C virus NS5B polymerase.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Porcari, A., et al.: J. Med. Chem., 41, 1252 (1998); Ishida, T., et al.: Bioorg. Med. Chem. Lett., 16, 1859 (2006)

Formula: C₈H₆BrF₃

Colore e forma: Neat

Peso molecolare: 239.03

Ref: TR-T790585

4-(Trifluoromethyl)benzyl bromide

CAS: 402-49-3

4-Trifluoromethylbenzyl bromide is a choline derivative that acts as an anticancer agent. It is structurally similar to the anticancer drug doxorubicin, which has been shown to be effective against breast cancer and leukemia. 4-Trifluoromethylbenzyl bromide interacts with cellular proteins, including choline kinase, and inhibits the mitochondrial pathway. This leads to cell death through apoptosis. The molecule also interacts with nucleotide bases such as thymine and cytosine in DNA, inhibiting transcription and replication. 4-Trifluoromethylbenzyl bromide binds strongly to the hydroxyl group of cholesterol by an electrophilic substitution mechanism to form a covalent bond with its hydroxy group. The molecule can also bind to chloride ions by an ionic bond.

Formula: C₈H₆BrF₃

Purezza: Min. 95%

Colore e forma: White Powder

Peso molecolare: 239.03 g/mol

Ref: 3D-FT34370