CAS 405911-17-3

Acido 2-[3-[3-[[2-cloro-3-(trifluorometil)benzil](2,2-difeniletil)amino]propossi]fenil]acetico cloridrato

Descrizione:

Acido 2-[3-[3-[[2-cloro-3-(trifluorometil)benzil](2,2-difeniletil)amino]propossi]fenil]acetico cloridrato, con numero CAS 405911-17-3, è un composto organico sintetico caratterizzato dalla sua struttura complessa, che include un moiety benzilico cloro-sostituito e un gruppo trifluorometilico. Questo composto è tipicamente classificato come un agente farmaceutico, potenzialmente in grado di mostrare proprietà rilevanti per applicazioni terapeutiche. La sua forma di sale cloridrico migliora la solubilità in ambienti acquosi, rendendolo adatto per varie formulazioni. La presenza di più anelli aromatici e gruppi funzionali suggerisce interazioni potenziali con bersagli biologici, che possono contribuire ai suoi effetti farmacologici. Inoltre, si sa che il gruppo trifluorometilico influisce sulla lipofilia e sulla stabilità metabolica, che sono fattori critici nel design dei farmaci. Come per molti composti di questa natura, i profili di sicurezza ed efficacia dovrebbero essere stabiliti attraverso test rigorosi, inclusi studi in vitro e in vivo, per determinare la sua idoneità all'uso clinico.

Formula: C₃₃H₃₂Cl₂F₃NO₃

Sinonimi:

• 2-[3-[3-[[2-Chloro-3-(Trifluoromethyl)Phenyl]Methyl-(2,2-Diphenylethyl)Amino]Propoxy]Phenyl]Acetic Acid,Hydrochloride
• GW3965 hydrochloride
• [3-(3-{[2-Chloro-3-(trifluoromethyl)benzyl](2,2-diphenylethyl)amino}propoxy)phenyl]acetic acid hydrochloride (1:1)
• Benzeneacetic acid, 3-[3-[[[2-chloro-3-(trifluoromethyl)phenyl]methyl](2,2-diphenylethyl)amino]propoxy]-, hydrochloride (1:1)

2-[3-[3-[[2-Chloro-3-(trifluoromethyl)benzyl](2,2-diphenylethyl)amino]propoxy]phenyl]acetic acid hydrochloride

CAS: 405911-17-3

Formula: C₃₃H₃₂Cl₂F₃NO₃

Purezza: 98%

Colore e forma: Solid

Peso molecolare: 618.5133

Ref: IN-DA003QTS

GW3965 hydrochloride

CAS: 405911-17-3

GW3965 hydrochloride

Purezza: ≥98%

Peso molecolare: 618.51g/mol

Ref: 54-BUP13070

2-[3-[3-[[2-Chloro-3-(Trifluoromethyl) Benzyl](2,2-Diphenylethyl)Amino]Propoxy]Phenyl] Acetic Acid Hydrochloride

CAS: 405911-17-3

2-[3-[3-[[2-Chloro-3-(Trifluoromethyl) Benzyl](2,2-Diphenylethyl)Amino]Propoxy]Phenyl] Acetic Acid Hydrochloride

Purezza: 98%

Peso molecolare: 618.51g/mol

Ref: 54-PC108907

GW3965 hydrochloride

CAS: 405911-17-3

Formula: C₃₃H₃₁F₃ClNO₃·HCl

Peso molecolare: 618.51

Ref: 7W-GL6745

GW3965 Hydrochloride

CAS: 405911-17-3

Formula: C₃₃H₃₁ClF₃NO₃·HCl

Purezza: >97.0%(HPLC)(qNMR)

Colore e forma: Colorless to Light yellow clear liquid

Peso molecolare: 618.52

Ref: 3B-G0655

GW3965 HCl

CAS: 405911-17-3

Formula: C₃₃H₃₁ClF₃NO₃·HCl

Colore e forma: Pale Brown Solid

Peso molecolare: 582.06 36.46

Ref: 4Z-K-031052

GW3965 hydrochloride

CAS: 405911-17-3

GW3965 hydrochloride (GW3965 HCl) is an effective and specific LXR agonist for hLXRα/β (EC50: 190/30 nM).

Formula: C₃₃H₃₁ClF₃NO₃·HCl

Purezza: 98.9% - 99.51%

Colore e forma: Solid

Peso molecolare: 618.51

Ref: TM-T6310

GW 3965 Hydrochloride

Prodotto controllato

CAS: 405911-17-3

Applications GW3965 Hydrochloride, is a potent, selective liver X receptor (LXR) agonist for hLXRα and hLXR. GW3965 has shown potent anti-inflammatory activity in both irritant and allergic contact models of dermatitis, requiring the participation of both LXRα and LXRβ.
References Fowler, A.J., et. al.: J. Invest. Dermatol., 120, 246 (2003)

Formula: C₃₃H₃₁ClF₃NO₃•HCl

Colore e forma: Neat

Peso molecolare: 582.053646

Ref: TR-G930985

GW 3965 hydrochloride

CAS: 405911-17-3

GW 3965 hydrochloride is a selective liver X receptor (LXR) agonist, which is a synthetic compound derived through pharmaceutical research aimed at modulating lipid metabolism. It functions by binding to and activating LXRs, which are nuclear receptors that regulate the expression of genes involved in cholesterol, fatty acid, and glucose homeostasis. Upon activation, these receptors influence the transcription of various target genes, leading to increased cholesterol efflux, decreased intestinal cholesterol absorption, and modulation of inflammatory responses.

Formula: C₃₃H₃₁ClF₃NO₃•HCl

Purezza: Min. 95%

Peso molecolare: 618.51 g/mol

Ref: 3D-FG103816