CAS 41767-29-7

Fluocortina butilica

Descrizione:

Fluocortina butilica, identificato dal suo numero CAS 41767-29-7, è un corticosteroide sintetico con proprietà anti-infiammatorie e immunosoppressive. È utilizzato principalmente in dermatologia per il trattamento di varie condizioni cutanee, tra cui eczema e psoriasi. La sostanza mostra un'alta affinità per i recettori dei glucocorticoidi, il che le consente di modulare efficacemente le risposte infiammatorie. Fluocortina butilica è caratterizzato dalla sua capacità di ridurre arrossamento, gonfiore e prurito associati a disturbi infiammatori della pelle. Viene tipicamente formulato in preparazioni topiche, come creme o unguenti, per applicazione localizzata. La farmacocinetica di Fluocortina butilica suggerisce che ha un profilo di assorbimento favorevole quando applicato sulla pelle, portando a risultati terapeutici efficaci con effetti collaterali sistemici minimi. Come con altri corticosteroidi, l'uso prolungato può portare ad atrofia cutanea o ad altri effetti avversi locali, richiedendo un attento monitoraggio e l'adesione alle linee guida di utilizzo prescritte. In generale, Fluocortina butilica è un agente prezioso nella gestione delle malattie infiammatorie della pelle.

Formula: C₂₆H₃₅FO₅

InChI: InChI=1/C26H35FO5/c1-5-6-9-32-24(31)23(30)21-14(2)10-17-16-12-19(27)18-11-15(28)7-8-25(18,3)22(16)20(29)13-26(17,21)4/h7-8,11,14,16-17,19-22,29H,5-6,9-10,12-13H2,1-4H3/t14-,16+,17+,19+,20+,21-,22-,25+,26+/m1/s1

InChI key: InChIKey=XWTIDFOGTCVGQB-FHIVUSPVSA-N

SMILES: C[C@@]12[C@]([C@]3([C@@]([C@]4(C)C([C@@H](F)C3)=CC(=O)C=C4)([C@@H](O)C1)[H])[H])(C[C@@H](C)[C@@H]2C(C(OCCCC)=O)=O)[H]

Sinonimi:

• 6-alpha-Fluor-11-beta-hydroxy-16-alpha-methyl-3,20-dioxo-1,4-pregnadien-21-saure-butylester
• Butyl (6Alpha,8Xi,9Xi,10Xi,11Beta,13Xi,16Alpha,17Xi)-6-Fluoro-11-Hydroxy-16-Methyl-3,20-Dioxopregna-1,4-Dien-21-Oate
• Butyl (6Α,11Β,16Α)-6-Fluoro-11-Hydroxy-16-Methyl-3,20-Dioxopregna-1,4-Dien-21-Oate
• Butyl 6-alpha-fluoro-11-beta-hydroxy-16-alpha-methyl-3,20-dioxo-1,4-pregnadien-21-oate
• Butyl 6alpha-fluoro-11beta-hydroxy-16alpha-methyl-3,20-dioxopregna-1,4-dien-21-oate
• Butyl 6α-fluoro-11β-hydroxy-3,20-dioxo-16α-methyl-1,4-pregnadien-21-oate
• Fluocortin butyl
• Fluocortin butyl [USAN:BAN]
• Fluocortin butyl ester
• Pregna-1,4-dien-21-oic acid, 6-fluoro-11-hydroxy-16-methyl-3,20-dioxo-, butyl ester (6alpha,11beta,16alpha)-
• Pregna-1,4-dien-21-oic acid, 6-fluoro-11-hydroxy-16-methyl-3,20-dioxo-, butyl ester, (6α,11β,16α)-
• Sh K 203
• Unii-6N7Oa9Mo7O
• Varlane
• Vaspit
• Butyl 6a-fluoro-11β-hydroxy-16α-methyl-3,20-dioxopregna-1,4-dien-21-oate
• Butyl 6α-fluoro-11β-hydroxy-16α-methyl-3,20-dioxopregna-1,4-dien-21-oate
• (6α,11β,16α)-6-Fluoro-11-hydroxy-16-Methyl-3,20-dioxopregna-1,4-dien-21-oic Acid Butyl Ester
• FLUOCORTINBUTYL

Fluocortin butyl ester

Prodotto controllato

CAS: 41767-29-7

Fluocortin butyl ester (FB) is a pharmacological treatment that is used to treat inflammation, allergies, and skin diseases. It belongs to the class of corticosteroids and is an active metabolite of hydrocortisone. FB has been shown to bind to glucocorticoid receptors in the cytoplasm and nucleus of cells. This binding inhibits transcription and translation of proteins involved in inflammatory processes. FB has also been shown to inhibit the production of pro-inflammatory cytokines such as interleukin-1β or tumor necrosis factor α (TNF-α). Fluocortin butyl ester has been used as a topical anti-inflammatory agent for the treatment of alopecia areata (hair loss) as well as other inflammatory skin diseases.

Formula: C₂₆H₃₅FO₅

Purezza: Min. 95%

Peso molecolare: 446.55 g/mol

Ref: 3D-FF23335

Fluocortin butyl ester

CAS: 41767-29-7

Fluocortin butyl ester is a topical corticosteroid without systemic effects, effective in treating perennial rhinitis.

Formula: C₂₆H₃₅FO₅

Colore e forma: Solid

Peso molecolare: 446.55

Ref: TM-T62654