CAS: 425386-60-3 - Semagacestat

Formula: C₁₉H₂₇N₃O₄

InChI: InChI=1S/C19H27N3O4/c1-11(2)16(23)18(25)20-12(3)17(24)21-15-14-8-6-5-7-13(14)9-10-22(4)19(15)26/h5-8,11-12,15-16,23H,9-10H2,1-4H3,(H,20,25)(H,21,24)/t12-,15-,16-/m0/s1

InChI key: InChIKey=PKXWXXPNHIWQHW-RCBQFDQVSA-N

SMILES: O=C(NC(C(=O)NC1C(=O)N(C)CCC=2C=CC=CC21)C)C(O)C(C)C

Sinonimi:

• (2S)-2-Hydroxy-3-methyl-N-[(1S)-1-methyl-2-oxo-2-[[(1S)-2,3,4,5-tetrahydro-3-methyl-2-oxo-1H-3-benzazepin-1-yl]amino]ethyl]butanamide
• (2S)-2-hydroxy-3-methyl-N-[(1S)-1-methyl-2-{[(1S)-3-methyl-2-oxo-2,3,4,5-tetrahydro-1H-3-benzazepin-1-yl]amino}-2-oxoethyl]butanamide
• Butanamide, 2-hydroxy-3-methyl-N-[(1S)-1-methyl-2-oxo-2-[[(1S)-2,3,4,5-tetrahydro-3-methyl-2-oxo-1H-3-benzazepin-1-yl]amino]ethyl]-, (2S)-
• Ly 450139

Semagacestat

CAS: 425386-60-3

• Formula: C₁₉H₂₇N₃O₄
• Purezza: 98%
• Colore e forma: Solid
• Peso molecolare: 361.4354

Semagacestat

CAS: 425386-60-3

Semagacestat (LY450139) (LY450139) is a γ-secretase blocker for Aβ42/Aβ40/Aβ38 (IC50: 10.9/12.1/12.0 nM) and also inhibits …

• Formula: C₁₉H₂₇N₃O₄
• Purezza: 97.1% - 99.11%
• Colore e forma: Solid
• Peso molecolare: 361.44

Semagacestat

CAS: 425386-60-3

Applications Semagacestat is an inhibitor of the γ-secretase enzyme. γ-Secretase enzyme is pivotal in the …

• Formula: C₁₉H₂₇N₃O₄
• Colore e forma: Neat
• Peso molecolare: 361.44

SEMAGACESTAT

CAS: 425386-60-3

• Purezza: 95.0%
• Colore e forma: Liquid
• Peso molecolare: 361.4419860839844

Semagacestat

CAS: 425386-60-3

γ-secretase inhibitor; inhibits notch signaling

• Formula: C₁₉H₂₇O₄N₃
• Purezza: Min. 95%
• Peso molecolare: 361.44 g/mol