CAS 427-51-0

Acetato di ciproterone

Descrizione:

Acetato di ciproterone è uno steroide antiandrogeno sintetico e progestinico, utilizzato principalmente nel trattamento di condizioni come disturbi dipendenti dagli androgeni, inclusi hirsutismo e acne, così come nella terapia ormonale per donne transgender. Funziona bloccando gli effetti degli androgeni, come il testosterone, a livello del recettore, e mostra anche attività progestazionale. Il composto è caratterizzato dalla sua formula chimica C22H27ClO3 e da un peso molecolare di circa 403,91 g/mol. Acetato di ciproterone è tipicamente somministrato per via orale ed è noto per la sua relativamente alta biodisponibilità. È solubile in solventi organici come etanolo e cloroformio, ma ha una solubilità limitata in acqua. La sostanza è spesso formulata in varie forme di dosaggio, comprese compresse e soluzioni iniettabili. Gli effetti collaterali possono includere aumento di peso, cambiamenti dell'umore e potenziali impatti sulla funzione epatica, richiedendo monitoraggio durante il trattamento. A causa della sua attività ormonale, Acetato di ciproterone è controindicato in alcune popolazioni, comprese le persone in gravidanza.

Formula: C₂₄H₂₉ClO₄

InChI: InChI=1S/C24H29ClO4/c1-12(26)24(29-13(2)27)8-6-16-14-10-20(25)19-11-21(28)15-9-18(15)23(19,4)17(14)5-7-22(16,24)3/h10-11,14-18H,5-9H2,1-4H3/t14-,15+,16-,17-,18-,22-,23-,24-/m0/s1

InChI key: InChIKey=UWFYSQMTEOIJJG-FDTZYFLXSA-N

SMILES: C[C@]12[C@@]3([C@@](C3)(C(=O)C=C1C(Cl)=C[C@@]4([C@@]2(CC[C@@]5(C)[C@]4(CC[C@]5(OC(C)=O)C(C)=O)[H])[H])[H])[H])[H]

Sinonimi:

• (1R,7aR,8aS,8bS,10aS)-1-acetyl-5-chloro-8b,10a-dimethyl-7-oxo-1,2,3,3a,3b,7,7a,8,8a,8b,8c,9,10,10a-tetradecahydrocyclopenta[a]cyclopropa[g]phenanthren-1-yl acetate
• (1β,2β)-17-(Acetyloxy)-6-chloro-1,2-dihydro-3′H-cyclopropa[1,2]pregna-1,4,6-triene-3,20-dione
• 1,2-alpha-Methylene-6-chloro-(sup 4,6)-pregnadiene-17-alpha-ol-3,20-dione 17-alpha-acetate
• 1,2-alpha-Methylene-6-chloro-delta(sup 6)-17-alpha-hydroxyprogesterone acetate
• 1,2-alpha-Methylene-6-chloro-pregna-4,6-diene-3,20-dione 17-alpha-acetate
• 1,2α-Methylene-6-chloro-17α-acetoxy-4,6-pregnadiene-3,20-dione
• 1,2α-Methylene-6-chloro-pregna-4,6-diene-3,20-dione 17α-acetate
• 1,2α-Methylene-6-chloro-Δ4,6-pregnadien-17α-ol-3,20-dione acetate
• 1,2α-Methylene-6-chloro-Δ^4,6-pregnadien-17α-ol-3,20-dione acetate
• 17-acetate de 6-chloro-1-β,2-β-dihydro-17-hydroxy-3'H-cyclopropa[1,2]pregna-1,4,6-triene-3,20-dione
• 17-acetato de 6-cloro-1-β,2-β-dihidro-17-hidroxi-3'H-ciclopropa[1,2]pregna-1,4,6-trieno-3,20-diona
• 17-alpha-Acetoxy-6-chloro-1-alpha,2-alpha-methylenepregna-4,6-diene-3,20-dione
• 17α-Acetoxy-6-chloro-1α,2α-methylenepregna-4,6-diene-3,20-dione
• 3'H-Cyclopropa(1,2)pregna-1,4,6-triene-3,20-dione, 17-(acetyloxy)-6-chloro-1,2-dihydro-, (1beta,2beta)-
• 3'H-Cyclopropa(1,2)pregna-1,4,6-triene-3,20-dione, 6-chloro-1-beta,2-beta-dihydro-17-hydroxy-, acetate
• 3'H-Cyclopropa[1,2]pregna-1,4,6-triene-3,20-dione
• 3'H-Cyclopropa[1,2]pregna-1,4,6-triene-3,20-dione, 17-(acetyloxy)-6-chloro-1,2-dihydro-, (1β,2β)-
• 3'H-Cyclopropa[1,2]pregna-1,4,6-triene-3,20-dione, 6-chloro-1β,2β-dihydro-17-hydroxy-, acetate
• 3′H-Cyclopropa[1,2]pregna-1,4,6-triene-3,20-dione
• 3′H-Cyclopropa[1,2]pregna-1,4,6-triene-3,20-dione, 17-(acetyloxy)-6-chloro-1,2-dihydro-, (1β,2β)-
• 3′H-Cyclopropa[1,2]pregna-1,4,6-triene-3,20-dione, 6-chloro-1β,2β-dihydro-17-hydroxy-, acetate
• 6-Chlor-1-β,2-β-dihydro-17-hydroxy-3'H-cyclopropa[1,2]pregna-1,4,6-trien-3,20-dion-17-acetat
• 6-Chlor-delta(sup 6)-1,2-alpha-methylen-17-alpha-hydroxyprogesteronacetat
• 6-Chlor-delta(sup 6)-1,2-alpha-methylen-17-alpha-hydroxyprogesteronacetat [German]
• 6-Chloro-1,2-alpha-methylene-17-alpha-hydroxy-delta(sup 6)-progesterone acetate
• 6-Chloro-1,2-alpha-methylene-6-dehydro-17-alpha-hydroxyprogesterone acetate
• 6-Chloro-1,2α-methylene-17α-hydroxy-Δ6-progesterone acetate
• 6-Chloro-1,2α-methylene-17α-hydroxy-Δ⁶-progesterone acetate
• 6-Chloro-1,2α-methylene-6-dehydro-17α-hydroxyprogesterone acetate
• 6-Chloro-1-beta,2-beta-dihydro-17-hydroxy-3'H-cyclopropa(1,2)pregna-1,4,6-triene-3,20-dione 17-acetate
• 6-Chloro-17-hydroxy-1-alpha,2-alpha-methylenepregna-4,6-diene-3,20-dione acetate
• 6-Chloro-17-hydroxy-1α,2α-methylenepregna-4,6-diene-3,20-dione acetate
• 6-Chloro-1beta,2beta-dihydro-17-hydroxy-3'H-cyclopropa(1,2)-pregna-1,4,6-triene-3,20-dione acetate
• 6-Chloro-delta(sup 6)-1,2-alpha-methylene-17-alpha-hydroxyprogesterone acetate
• 6-Chloro-delta-6-1,2alpha-methylene-17alpha-hydroxyprogesterone acetate
• 6-chloro-1-β,2-β-dihydro-17-hydroxy-3'H-cyclopropa[1,2]pregna-1,4,6-triene-3,20-dione 17-acetate
• Androcur
• Androcur Depot
• CPA
• Ccris 4385
• Cyclopropa[1,2]cyclopenta[a]phenanthrene, 3′H-cyclopropa[1,2]pregna-1,4,6-triene-3,20-dione deriv.
• Cyprostat
• Cyproteron acetate
• Cyproteron-R acetate
• Cyproterone 17-O-acetate
• Cyproterone 17alpha-acetate
• Cyproterone 17α-acetate
• Cyproviron
• Hsdb 3592
• Nsc 81430
• Pregna-4,6-diene-3,20-dione, 6-chloro-17-hydroxy-1-alpha,2-alpha-methylene-, acetate
• Pregna-4,6-diene-3,20-dione, 6-chloro-17-hydroxy-1α,2α-methylene-, acetate
• Sh 714
• Sh 80714

Cyproterone Acetate

CAS: 427-51-0

Colore e forma: Neat

Ref: 61-FOR0215.00

CYPROTERONE ACETATE CRS

CAS: 427-51-0

CYPROTERONE ACETATE CRS

Formula: C₂₄H₂₉ClO₄

Colore e forma: Added Modified

Peso molecolare: 416.9377

Ref: 41-C3283000

CYPROTERONE IMPURITY MIXTURE CRS

CAS: 427-51-0

CYPROTERONE IMPURITY MIXTURE CRS

Colore e forma: Added Modified

Ref: 41-Y0001223

Cyproterone acetate

CAS: 427-51-0

Cyproterone acetate

Formula: C₂₄H₂₉ClO₄

Purezza: 99.9%

Colore e forma: White

Peso molecolare: 416.17544

Ref: 47-688

CYPROTERONE ACETATE FOR PEAK IDENTIFICATION CRS

CAS: 427-51-0

CYPROTERONE ACETATE FOR PEAK IDENTIFICATION CRS

Colore e forma: Added Modified

Ref: 41-Y0001390

Cyproteroneacetate

CAS: 427-51-0

Formula: C₂₄H₂₉ClO₄

Purezza: 98%

Colore e forma: Solid

Peso molecolare: 416.9377

Ref: IN-DA00ILMR

Cyproterone acetate

CAS: 427-51-0

Cyproterone acetate (Cyproterone 17-O-acetate) binds the androgen receptor (AR), thereby preventing androgen-induced receptor activation in target tissues and

Formula: C₂₄H₂₉ClO₄

Purezza: 98.43% - 99.83%

Colore e forma: Crystals From Diisopropyl Ether Odour

Peso molecolare: 416.94

Ref: TM-T1167

Cyproterone acetate

CAS: 427-51-0

Cyproterone acetate

Purezza: ≥98%

Peso molecolare: 416.94g/mol

Ref: 54-BUP16707

Cyproterone Acetate-d3

CAS: 427-51-0

Formula: C₂₄H₂₆D₃ClO₄

Colore e forma: White To Off-White Solid

Peso molecolare: 419.96

Ref: 4Z-C-288

Cyproterone Acetate-d6

CAS: 427-51-0

Formula: C₂₄H₂₃D₆ClO₄

Peso molecolare: 422.98

Ref: 4Z-C-285

Cyproterone Acetate

CAS: 427-51-0

Formula: C₂₄H₂₉ClO₄

Colore e forma: White To Off-White Solid

Peso molecolare: 416.94

Ref: 4Z-C-283

Cyproterone Acetate

CAS: 427-51-0

Formula: C₂₄H₂₉ClO₄

Purezza: >98.0%(HPLC)

Colore e forma: White to Almost white powder to crystal

Peso molecolare: 416.94

Ref: 3B-C2942

Cyproterone acetate

Prodotto controllato

CAS: 427-51-0

Formula: C₂₄H₂₉ClO₄

Colore e forma: Neat

Peso molecolare: 416.94

Ref: 04-C11917100

Cyproterone Acetate

Prodotto controllato

CAS: 427-51-0

Formula: C₂₄H₂₉ClO₄

Colore e forma: Neat

Peso molecolare: 416.94

Ref: 86-MM0215.00

Cyproterone Acetate-13C2-d3

CAS: 427-51-0

Formula: C₂₂₁₃C₂H₂₆D₃ClO₄

Peso molecolare: 421.95

Ref: 4Z-C-284

Cyproterone acetate

CAS: 427-51-0

Formula: C₂₄H₂₉ClO₄

Colore e forma: White to almost white powder or crystals

Peso molecolare: 416.94

Ref: 7W-GP6849

Cyproterone Acetate

Prodotto controllato

CAS: 427-51-0

Formula: C₂₄H₂₉ClO₄

Colore e forma: White

Peso molecolare: 416.94

Ref: TR-C989100

Cyproterone acetate

Prodotto controllato

CAS: 427-51-0

Androgen receptor antagonist; apoptotic in hepatic cells

Formula: C₂₄H₂₉ClO₄

Purezza: Min. 98 Area-%

Colore e forma: Powder

Peso molecolare: 416.94 g/mol

Ref: 3D-FC20764

Cyproterone Acetate-d3 (Major)

Prodotto controllato

CAS: 427-51-0

Applications Cyproterone Acetate-d3, is the labeled analogue of Cyproterone Acetate (C989100), which combined with estrogen it is used in the treatment of acne.
References Moltz, L., et al.: Contraception, 21, 393 (1980), Hammerstein, J., et al.: J. Steroid Biochem., 29, 591 (1983)

Formula: C₂₄H₂₆D₃ClO₄

Colore e forma: Neat

Peso molecolare: 419.96

Ref: TR-C989103

Cyproterone Acetate-13C2,d3 (Major)

Prodotto controllato

CAS: 427-51-0

Applications Labelled Cyproterone Acetate. The free alcohol is an anti-androgen; the acetate is both an anti-androgen and a progestogen. Combined with estrogen it is used in the treatment of acne.
References Moltz, L., et al.: Contraception, 21, 393 (1980), Hammerstein, J., et al.: J. Steroid Biochem., 29, 591 (1983)

Formula: C₂₂₁₃C₂H₂₆D₃ClO₄

Colore e forma: Neat

Peso molecolare: 421.94

Ref: TR-C989102