CAS 43200-80-2

Zopiclone

Descrizione:

Zopiclone è un agente ipnotico non benzodiazepinico utilizzato principalmente per il trattamento dell'insonnia. Appartiene alla classe dei composti ciclopirrolone ed è caratterizzato dalle sue proprietà sedative e ansiolitiche. La formula chimica di Zopiclone è C17H17ClN6O3 e presenta una struttura unica che include un anello di pirrolone, che contribuisce ai suoi effetti farmacologici. Zopiclone agisce sul sistema nervoso centrale aumentando l'attività dell'acido gamma-aminobutirrico (GABA), un neurotrasmettitore che promuove il sonno e il rilassamento. Viene tipicamente somministrato in forma di compresse ed è noto per il suo rapido inizio d'azione, rendendolo efficace per la gestione a breve termine dei disturbi del sonno. Gli effetti collaterali comuni possono includere sonnolenza, vertigini e potenziale dipendenza con l'uso prolungato. A causa dei suoi effetti sedativi, si consiglia cautela nell'uso di macchinari o nella guida dopo aver assunto Zopiclone. Come con qualsiasi farmaco, è importante utilizzare Zopiclone sotto la guida di un professionista sanitario per mitigare i rischi e garantire un uso sicuro.

Formula: C₁₇H₁₇ClN₆O₃

InChI: InChI=1S/C17H17ClN6O3/c1-22-6-8-23(9-7-22)17(26)27-16-14-13(19-4-5-20-14)15(25)24(16)12-3-2-11(18)10-21-12/h2-5,10,16H,6-9H2,1H3

InChI key: InChIKey=GBBSUAFBMRNDJC-UHFFFAOYSA-N

SMILES: O(C(=O)N1CCN(C)CC1)C2N(C(=O)C=3C2=NC=CN3)C4=CC=C(Cl)C=N4

Sinonimi:

• (.+-.)-Zopiclone
• 5H-Pyrrolo[3,4-b]pyrazine, 1-piperazinecarboxylic acid deriv.
• Amoban
• Amovane
• Hypnor
• Imoclone
• Imovance
• Imovane
• Rp 27267
• Sopivan
• Zimovane
• Zopiclon
• Zopiclona
• 1-Piperazinecarboxylic acid, 4-methyl-, 6-(5-chloro-2-pyridinyl)-6,7-dihydro-7-oxo-5H-pyrrolo[3,4-b]pyrazin-5-yl ester
• 4-({[(5R)-6-(5-chloropyridin-2-yl)-7-oxo-6,7-dihydro-5H-pyrrolo[3,4-b]pyrazin-5-yl]oxy}carbonyl)-1-methylpiperazin-1-ium
• 4-({[(5S)-6-(5-chloropyridin-2-yl)-7-oxo-6,7-dihydro-5H-pyrrolo[3,4-b]pyrazin-5-yl]oxy}carbonyl)-1-methylpiperazin-1-ium
• 4-Methyl-1-piperazinecarboxylic acid 6-(5-chloro-2-pyridinyl)-6,7-dihydro-7-oxo-5H-pyrrolo[3,4-b]pyrazin-5-yl ester
• 27267r.p.
• 27267 R.P.
• 4-methyl-,6-(5-chloro-2-pyridinyl)-6,7-dihydro-7-1-piperazinecarboxylicaci
• 4-Methyl-1-piperazinecarboxylic acid ester with 6-(5-chloro-2-pyridyl)-6,7-dihydro-7-hydroxy-5H-pyrrolo[3,4-b]pyrazin-5-one
• Zopicclone
• 6-(5-Chloro-2-pyridinyl)-7-oxo-6,7-dihydro-5H-pyrrolo[3,4-b]pyrazin-5-yl 4-methyl-1-piperazinecarboxylate
• 4-Methyl-1-piperazine-carboxylic Acid 6-(5-chloro-2-pyridinyl)-6,7-dihydro-7-oxo-5H-pyrrolo[3,4-b]pyrazin-5-yl Ester
• 4-METHYLPIPERAZINE-1-CARBOXYLIC ACID 6-(5-CHLORO-PYRIDIN-2-YL)-7-OXO-6,7-DIHYDRO-5H-PYRROLO[3,4-B]PY

Zopiclone 1.0 mg/ml in Acetonitrile

CAS: 43200-80-2

Colore e forma: Single Solution

Ref: 61-AMP0149.00-11

Zopiclone

CAS: 43200-80-2

Colore e forma: Neat

Ref: 61-FOR0149.00

Zopiclone, 1mg/ml in Acetonitrile

CAS: 43200-80-2

Colore e forma: Single Solution

Ref: LP-ZOP-921-FB-1LA

Zopiclone

Prodotto controllato

CAS: 43200-80-2

Colore e forma: Neat

Ref: LP-ZOP-921-FB-10

Zopiclone

CAS: 43200-80-2

Formula: C₁₇H₁₇ClN₆O₃

Peso molecolare: 388.81

Ref: 4Z-Z-0637

Zopiclone

CAS: 43200-80-2

Formula: C₁₇H₁₇ClN₆O₃

Peso molecolare: 388.81

Ref: 7W-GP1081

(±)-Zopiclone-d3 (N-methyl-d3)

Prodotto controllato

CAS: 1398066-10-8, 43200-80-2

Purezza: 99 atom % D

Colore e forma: White Solid

Peso molecolare: 391.83

Ref: 3U-D7385

Zopiclone

CAS: 43200-80-2

Colore e forma: Neat

Ref: 86-MM0149.00

Zopiclone

Prodotto controllato

CAS: 43200-80-2

Formula: C₁₇H₁₇ClN₆O₃

Colore e forma: Neat

Peso molecolare: 388.81

Ref: 04-C17978000

Zopiclone-d4

CAS: 43200-80-2

Formula: C₁₇H₁₃D₄ClN₆O₃

Peso molecolare: 392.84

Ref: 4Z-Z-0615

Zopiclone

Prodotto controllato

CAS: 43200-80-2

Stability Hygroscopic
Applications Cyclopyrrolone member of a family of non-benzodiazepine GABAA receptor agonists. This is a controlled substance (depressant) in the US but not in Canada. Sedative, hypnotic.
References Noble, S., et al.: Drugs, 55, 277 (1998), Musch, B., et al.: Int. J. Clin. Psychopharmacol., 5, 147 (1990),

Formula: C₁₇H₁₇ClN₆O₃

Colore e forma: White To Off-White

Peso molecolare: 388.81

Ref: TR-Z700500

Zopiclone

Prodotto controllato

CAS: 43200-80-2

Zopiclone is a benzodiazepine that has been shown to have potent inducers of hepatic enzymes. It is used for the treatment of insomnia, but long-term use may lead to tolerance and dependence. Zopiclone binds to the receptor site for GABA, which is a neurotransmitter. It also affects other neurotransmitters such as monoamines, which are involved in mood control and arousal. Zopiclone has been shown to be beneficial in patients with congestive heart failure, although it can cause orthostatic hypotension. The matrix effect of zopiclone is significant, leading to drug interactions with other drugs taken at the same time. Zopiclone has been shown to be effective in treating chronic insomnia and its long-term efficacy appears to be good.

Formula: C₁₇H₁₇ClN₆O₃

Peso molecolare: 388.81 g/mol

Ref: 3D-W-106239

Zopiclone

Prodotto controllato

CAS: 43200-80-2

Antagonist of GABA(A); hypnotic agent

Formula: C₁₇H₁₇ClN₆O₃

Purezza: Min. 95%

Colore e forma: Powder

Peso molecolare: 388.81 g/mol

Ref: 3D-FZ156793

ZOPICLONE CRS - * PSY

Prodotto controllato

CAS: 43200-80-2

ZOPICLONE CRS - * PSY

Formula: C₁₇H₁₇ClN₆O₃

Colore e forma: Powder

Peso molecolare: 388.8083

Ref: 41-Z3000000

Zopiclone

Prodotto controllato

CAS: 43200-80-2

Zopiclone

Formula: C₁₇H₁₇CIN₆O₃

Purezza: 99.8%

Colore e forma: White To Off-White

Peso molecolare: 492.04069

Ref: 47-812

Zopiclone (1 mg/mL in Acetonitrile)

Prodotto controllato

CAS: 43200-80-2

Formula: C₁₇H₁₇ClN₆O₃

Colore e forma: Colourless

Peso molecolare: 388.81

Ref: TR-KIT0130