CAS 4342-03-4

Dacarbazina

Descrizione:

Dacarbazina, con il numero CAS 4342-03-4, è un agente antineoplastico utilizzato principalmente nella chemioterapia per il trattamento di vari tipi di cancro, inclusi melanoma e linfoma di Hodgkin. È classificato come un agente alchilante, il che significa che agisce interferendo con il processo di replicazione del DNA nelle cellule tumorali, portando infine alla morte cellulare. Dacarbazina è una polvere cristallina bianca o bianco sporco che è solubile in acqua e ha un peso molecolare relativamente basso. La sua formula chimica è C6H10N4O2S, ed è spesso somministrato per via endovenosa. Il farmaco è noto per avere una serie di effetti collaterali, tra cui nausea, vomito e mielosoppressione, il che richiede un attento monitoraggio durante il trattamento. Dacarbazina è tipicamente usato in combinazione con altri agenti chemioterapici per aumentare la sua efficacia e migliorare i risultati per i pazienti. Come con tutti gli agenti chemioterapici, il suo uso dovrebbe essere guidato da un professionista sanitario, considerando il tipo specifico di cancro e lo stato di salute del paziente.

Formula: C₆H₁₀N₆O

InChI: InChI=1/C6H10N6O/c1-12(2)11-10-6-4(5(7)13)8-3-9-6/h3H,1-2H3,(H2,7,13)(H,8,9)/b11-10+

InChI key: InChIKey=FDKXTQMXEQVLRF-UHFFFAOYSA-N

SMILES: N(=NN(C)C)C1=C(C(N)=O)N=CN1

Sinonimi:

• (4E)-4-(3,3-dimethyltriazanylidene)-4H-imidazole-5-carboxamide
• (Dimethyltriazeno)imidazolecarboxamide
• 1H-Imidazole-4-carboxamide, 5-(3,3-dimethyl-1-triazen-1-yl)-
• 1H-Imidazole-4-carboxamide, 5-(3,3-dimethyl-1-triazenyl)-
• 1H-Imidazole-4-carboxamide, 5-[2-(dimethylamino)diazenyl]-
• 4(or 5)-(3,3-Dimethyl-1-triazeno)imidazole-5(or 4)-carboxamide
• 4-(3,3-dimethyltriazanylidene)-4H-imidazole-5-carboxamide
• 4-(Dimethyltriazeno)imidazole-5-carboxamide
• 5(4)-(3,3-Dimethyl-1-triazeno)imidazole-4(5)-carboxamide
• 5(or 4)-(3,3-Dimethyl-1-triazeno)imidazole-4(or 5)carboxamide
• 5-(3,3'-Dimethyl-1-triazeno)imidazole-4-carboxamide
• 5-(3,3-Dimethyl-1-triazen-1-yl)-1H-imidazole-4-carboxamide
• 5-(3,3-Dimethyl-1-triazenyl)-1H-imidazole-4-carboxamide
• 5-(3,3-Dimethyl-1-triazenyl)imidazole-4-carboxamide
• 5-(3,3-Dimethyltriazeno)imidazole-4-carboxamide
• 5-(3,3-dimethyltriaz-1-en-1-yl)-1H-imidazole-4-carboxamide
• 5-(Dimethyltriazeno)imidazole-4-carboxamide
• 5-[(1E)-3,3-dimethyltriaz-1-en-1-yl]-1H-imidazole-4-carboxamide
• Biocarbazine R
• DIC
• DTIC-Dome
• Dacarbasine
• Dacarbazin
• Dacarbazino
• Deticene
• Detimedac
• Dtic
• Dtie
• Icdmt
• Icdt
• Imidazole-4(or 5)-carboxamide, 5(or 4)-(3,3-dimethyl-1-triazeno)-
• Imidazole-4-carboxamide, 5-(3,3-dimethyl-1-triazeno)-
• Nci C04717
• Nsc 45388
• TOSLAB 25071
• 5-(3,3-dimethyl-1-triazeno)-imidazole-4-carboxamid
• DACARBAZINE
• 4-(3,3-dimethyltriazeno)imidazole-5-carboxamide
• biocarbaziner
• 5-(3,3-dimethyl-1-triazeno1-imidazole-4-carboxamid
• 4-(5)-(3,3-dimethyl-1-triazeno)imidazole-5(4)-carboxamide
• 5-(3,3-dimethyl-1-triazenyl)-1h-imidazole-4-carboxamid

Dacarbazine

CAS: 4342-03-4

Formula: C₆H₁₀N₆O

Purezza: >98.0%(T)(HPLC)

Colore e forma: White to Light yellow powder to crystal

Peso molecolare: 182.19

Ref: 3B-D3634

Dacarbazine

CAS: 4342-03-4

Used in treatment of malignant melanoma and sarcomas. Generates methyl adducts to purine bases in DNA This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesa

Formula: C₆H₁₀N₆O

Peso molecolare: 182.18

Ref: 02-J61023

DACARBAZINE RS

CAS: 4342-03-4

DACARBAZINE RS

Formula: C₆H₁₀N₆O

Peso molecolare: 182.1832

Ref: 41-ICRS46471

Dacarbazine

CAS: 4342-03-4

Dacarbazine

Formula: C₆H₁₀N₆O

Colore e forma: Off-White. To. Light Yellow

Peso molecolare: 182.1832

Ref: 47-100

DACARBAZINE CRS

CAS: 4342-03-4

DACARBAZINE CRS

Formula: C₆H₁₀N₆O

Colore e forma: Crystalline Powder. White. Yellow. Powder.

Peso molecolare: 182.1832

Ref: 41-Y0000733

Dacarbazine

CAS: 4342-03-4

Compounds containing an unfused imidazole ring (whether or not hydrogenated) in the structure nesoi

Formula: C₆H₁₀N₆O

Colore e forma: Off-White White Powder

Peso molecolare: 182.09161

Ref: 45-1162308

5-[(1E)-dimethyltriaz-1-en-1-yl]-1H-imidazole-4-carboxamide

CAS: 4342-03-4

Formula: C₆H₁₀N₆O

Purezza: 98%

Colore e forma: Solid

Peso molecolare: 182.1832

Ref: IN-DA003P85

Dacarbazine

CAS: 4342-03-4

Dacarbazine (DTIC-Dome) is an antineoplastic agent. It has significant activity against melanomas.

Formula: C₆H₁₀N₆O

Purezza: 99.78% - 99.87%

Colore e forma: Ivory Microcrystaline Substance Physical Description White To Ivory Microcrystals Or Off-White Crystalline Solid (Ntp 1992)

Peso molecolare: 182.18

Ref: TM-T1120

Dacarbazine

CAS: 4342-03-4

Formula: C₆H₁₀N₆O

Purezza: 98.0 - 102.0 % (anhydrous substance)

Colore e forma: White to off-white or pale yellow crystalline powder

Peso molecolare: 182.18

Ref: 7W-GA1142

Dacarbazine

CAS: 4342-03-4

Dacarbazine

Purezza: 99%

Peso molecolare: 182.18g/mol

Ref: 54-OR1028861

Dacarbazine

CAS: 4342-03-4

Dacarbazine

Purezza: ≥98%

Peso molecolare: 182.18g/mol

Ref: 54-BUP14891

Dacarbazine

Prodotto controllato

CAS: 4342-03-4

Formula: C₆H₁₀N₆O

Colore e forma: Off-White To Light Yellow

Peso molecolare: 182.18

Ref: 86-MM1289.00

Dacarbazine

CAS: 4342-03-4

Formula: C₆H₁₀N₆O

Peso molecolare: 182.19

Ref: 4Z-D-090006

Dacarbazine

CAS: 4342-03-4

Dacarbazine is an antineoplastic agent that inhibits the division of cancer cells by acting as a prodrug to produce the active form, dacarbazine trioxide. It has been shown to be effective in vitro for the treatment of melanoma and other solid tumours. Dacarbazine has been used in combination with other chemotherapeutic agents, such as temozolomide, for the treatment of brain tumours and carcinoid syndrome. The drug is associated with acute toxicities, including myelosuppression, alopecia, nausea and vomiting. These side effects can be reduced using interferon-alfa-2b. Dacarbazine has also been shown to have mitochondrial membrane potential (MMP) stabilizing properties that are independent of its cytotoxic effects on tumour cells.

Formula: C₆H₁₀N₆O

Purezza: Min. 95%

Colore e forma: White Powder

Peso molecolare: 182.18 g/mol

Ref: 3D-FD01582

4-(Dimethyltriazeno)imidazole-5-carboxamide

CAS: 4342-03-4

Formula: C₆H₁₀N₆O

Purezza: 97.0%

Peso molecolare: 182.187

Ref: 10-F036541

4-[(1E)-3,3-dimethyltriaz-1-en-1-yl]-1H-imidazole-5-carboxamide

CAS: 4342-03-4

Purezza: 98%

Colore e forma: Solid

Peso molecolare: 182.1869965

Ref: 10-F801113