CAS 438-59-5

Cloridrato di 10,11-dideidronortriptilina

Descrizione:

Cloridrato di 10,11-dideidronortriptilina è un composto chimico che appartiene alla classe degli antidepressivi triciclici. È un derivato della nortriptilina, nota per il suo utilizzo nel trattamento della depressione e di alcuni tipi di dolore. Il composto presenta una struttura triciclica, caratterizzata da tre anelli interconnessi, che contribuiscono alla sua attività farmacologica. Come sale cloridrato, è tipicamente più solubile in acqua, facilitando il suo utilizzo nelle formulazioni farmaceutiche. Il composto agisce principalmente inibendo il riassorbimento di neurotrasmettitori come la norepinefrina e la serotonina, migliorando così l'umore e alleviando i sintomi depressivi. Le sue proprietà chimiche includono un peso molecolare specifico e un punto di fusione definito, che sono essenziali per la sua caratterizzazione e il controllo di qualità nelle applicazioni farmaceutiche. I profili di sicurezza ed efficacia sono critici e, come altri antidepressivi triciclici, può avere effetti collaterali, tra cui sedazione ed effetti anticolinergici. Una corretta gestione e dosaggio sono essenziali per minimizzare i rischi associati al suo utilizzo.

Formula: C₁₉H₂₀ClN

InChI: InChI=1/C19H19N.ClH/c1-20-14-6-11-19-17-9-4-2-7-15(17)12-13-16-8-3-5-10-18(16)19;/h2-5,7-13,20H,6,14H2,1H3;1H

InChI key: InChIKey=UZMPCPFDZYTEJG-UHFFFAOYSA-N

SMILES: C(CCNC)=C1C=2C(C=CC=3C1=CC=CC3)=CC=CC2.Cl

Sinonimi:

• 1-Propanamine, 3-(5H-dibenzo(a,d)cyclohepten-5-ylidene)-N-methyl-, hydrochloride (9CI)
• 1-Propanamine, 3-(5H-dibenzo[a,d]cyclohepten-5-ylidene)-N-methyl-, hydrochloride
• 1-Propanamine, 3-(5H-dibenzo[a,d]cyclohepten-5-ylidene)-N-methyl-, hydrochloride (1:1)
• 10,11-Didehydronortriptyline hydrochloride
• 10,11-thelda-Nortriptyline hydrochloride
• 3-(5H-dibenzo[a,d][7]annulen-5-ylidene)-N-methylpropan-1-amine hydrochloride (1:1)
• 5H-Dibenzo(a,d)cycloheptene-delta(sup 5),gamma-propylamine, N-methyl-, hydrochloride
• 5H-Dibenzo[a,d]cycloheptene-Δ^5,γ-propylamine, N-methyl-, hydrochloride
• N 7068 hydrochloride
• Norproheptatriene hydrochloride
• Ro 4-6011
• 3-(5H-Dibenzo(a,d)cyclohepten-5-ylidene)propyl(methyl)ammonium chloride
• 5H-Dibenzo[a,d]cycloheptene-Δ5,γ-propylamine, N-methyl-, hydrochloride
• Nortriptyline Impurity 2 (Nortriptyline EP Impurity B)
• Cyclobenzaprine USP RC B Q: What is the storage condition of
• 3-(5H-Dibenzo[a,d]cyclohepten-5-ylidene)-N-methyl-1-propanamine Hydrochloride
• Einecs 207-118-3
• Cyclobenzaprine USP RC B
• Desmethyl Cyclobenzaprine Hydrochloride
• 3-(5H-Dibenzo[a,d][7]annulen-5-ylid
• Cyclobenzaprine Related CoMpound B
• Cyclobenzaprine Impurity 2(Cyclobenzaprine USP RC B)
• Cyclobenzaprine USP Related Compound B as Hydrochloride
• N-desmethyl Cyclobenzaprine HCl (USP RC B)
• Nortriptyline EP Impurity B HCl
• Cyclobenzaprine impurity 2/Cyclobenzaprine USP Related Compound B/Desmethyl Cyclobenzaprine Hydrochloride/3-(5H-Dibenzo[a,d]cyclohepten-5-ylidene)-N-methyl-1-propanamine hydrochloride
• NORTRIPTYLINE EP IMPURITY B
• Cyclobenzaprine USP RC B Q: What is the CAS Number of
• Nortriptyline EP Impurity B HCl (N-Desmethyl Cyclobenzaprine HCl)
• Nortriptyline Hydrochloride Impurity B as Hydrochloride
• N-Desmethyl Cyclobenzaprine
• 3-(dibenzo[1,2-a:1',2'-e][7]annulen-11-ylidene)-N-methylpropan-1-amine
• N-Desmethyl Cyclobenzaprine Hydrochloride
• Nortriptyline Hydrochloride EP Impurity B as Hydrochloride
• Cyclobenzaprine USP Related Compound B
• Cyclobenzaprine DesMethyl HCl
• N-Desmethylcyclobenzaprine hydrochloride solution
• N-Desmethyl Cyclobenzaprine-d3
• Cyclobenzaprine Related Compound B (3-(5H-dibenzo[a,d]cyclohepten-5-ylidene)-N-methyl-1-propanamine (1154525)
• Cyclobenzaprine Related Compound B (10 mg) (3-(5H-dibenzo[a,d]cyclohepten-5-ylidene)-N-methyl-1-propanamine, hydrochloride)
• Cyclobenzaprine USP RC B Q: What are the applications of
• Desmethylcyclobenzaprine hydrochloride salt
• Cyclobenzaprine USP RC BQ: What is
• Cyclobenzaprine Related Compound B as Hydrochloride

N-Desmethylcyclobenzaprine Hydrochloride (Norcyclobenzaprine Hydrochloride) 1.0 mg/ml in Methanol (as free base)

CAS: 438-59-5

Colore e forma: Single Solution

Ref: 61-AMP0079.01-01

Cyclobenzaprine Related Compound B (3-(5H-dibenzo[a,d]cyclohepten-5-ylidene)-N-methyl-1-propanamine, hydrochloride)

CAS: 438-59-5

Aromatic monoamines and their derivatives, salts thereof, nesoi

Formula: C₁₉H₁₉N·HCl

Colore e forma: White Powder

Peso molecolare: 261.15175

Ref: 45-1154525

1-Propanamine,3-(5H-dibenzo[a,d]cyclohepten-5-ylidene)-N-methyl-,hydrochloride (1:1)

CAS: 438-59-5

Formula: C₁₉H₂₀ClN

Colore e forma: Solid

Peso molecolare: 297.8218

Ref: IN-DA0037GQ

Nortriptyline EP Impurity B HCl (Cyclobenzaprine USP Related Compound B, N-Desmethyl Cyclobenzaprine HCl)

CAS: 438-59-5

Formula: C₁₉H₁₉N·HCl

Peso molecolare: 261.37 36.46

Ref: 4Z-N-3621

3-(5H-Dibenzo[a,d][7]annulen-5-ylidene)-N-methylpropan-1-amine Hydrochloride (Norcyclobenzaprine Hydrochloride)

Prodotto controllato

CAS: 438-59-5

Formula: C₁₉H₁₉N·ClH

Colore e forma: Neat

Peso molecolare: 297.82

Ref: 86-MM0079.01

Desmethyl Cyclobenzaprine Hydrochloride

CAS: 438-59-5

Impurity Cyclobenzaprine USP Related Compound B
Applications Desmethyl Cyclobenzaprine (Cyclobenzaprine USP Related Compound B) is a metabolite of Cyclobenzaprine.
References Wang, R.W., et al.: Drug Metab. Dispos., 24, 786 (1996),

Formula: C₁₉H₁₉N·ClH

Colore e forma: Off-White

Peso molecolare: 297.82

Ref: TR-D291560

Nortriptyline EP Impurity B

CAS: 438-59-5

Formula: C₁₉H₁₉NHCl

Peso molecolare: 261.37 : 36.46

Ref: ST-EA-CP-N15002

Desmethyl cyclobenzaprine hydrochloride

CAS: 438-59-5

Desmethyl cyclobenzaprine hydrochloride is a metabolite of cyclobenzaprine, a drug used for the treatment of muscle spasms. Desmethyl cyclobenzaprine hydrochloride has been shown to have an increased potency for the termination of nerve impulses. These results were determined by in vivo studies using an assay on rat sciatic nerve and a study on human adrenergic receptors. This metabolite also shows potentiation effects with other drugs such as clonidine and prazosin, which are used to treat hypertension and anxiety, respectively. However, clinical relevance is still unknown due to the lack of data on desmethyl cyclobenzaprine hydrochloride's uptake and enhancement in humans.

Formula: C₁₉H₂₀ClN

Purezza: Min. 95%

Colore e forma: White To Off-White Solid

Peso molecolare: 297.82 g/mol

Ref: 3D-FD21256