CAS 439687-69-1

(2S,4R)-1-[(3R)-5-Cloro-1-[(2,4-dimetossifenil)sulfonil]-2,3-diidro-3-(2-metossifenil)-2-osso-1H-indol-3-il]-4-idrossi-N,N-dimetil-2-pirrolidin-carbossamide

Descrizione:

La sostanza chimica con il nome "(2S,4R)-1-[(3R)-5-Cloro-1-[(2,4-dimetossifenil)sulfonil]-2,3-diidro-3-(2-metossifenil)-2-osso-1H-indol-3-il]-4-idrossi-N,N-dimetil-2-pirrolidin-carbossamide" e numero CAS "439687-69-1" è un composto organico complesso caratterizzato dalla sua intricatissima struttura molecolare, che include più gruppi funzionali come sulfonammidi, amidi e gruppi idrossilici. Questo composto presenta un centro chirale, indicato dai descrittori stereochimici (2S,4R) e (3R), il che suggerisce che potrebbe mostrare specifica attività biologica o proprietà farmacologiche a causa della sua stereochimica. La presenza di sostituenti cloro e metossile sugli anelli aromatici contribuisce alla sua potenziale reattività e interazione con bersagli biologici. Inoltre, il moiety indolo è spesso associato a varie attività biologiche, rendendo questo composto di interesse nella chimica medicinale. La sua solubilità, stabilità e reattività dipenderebbero dalle condizioni specifiche, incluso il pH e il solvente, che sono critici per la sua applicazione in contesti di ricerca o terapeutici.

Formula: C₃₀H₃₂ClN₃O₈S

InChI: InChI=1S/C30H32ClN3O8S/c1-32(2)28(36)24-15-19(35)17-33(24)30(21-8-6-7-9-25(21)41-4)22-14-18(31)10-12-23(22)34(29(30)37)43(38,39)27-13-11-20(40-3)16-26(27)42-5/h6-14,16,19,24,35H,15,17H2,1-5H3/t19-,24+,30+/m1/s1

InChI key: InChIKey=NJXZWIIMWNEOGJ-WEWKHQNJSA-N

SMILES: O=C1[C@](C=2C(N1S(=O)(=O)C3=C(OC)C=C(OC)C=C3)=CC=C(Cl)C2)(N4[C@H](C(N(C)C)=O)C[C@@H](O)C4)C5=C(OC)C=CC=C5

Sinonimi:

• SSR 149415
• 2-Pyrrolidinecarboxamide, 1-[(3R)-5-chloro-1-[(2,4-dimethoxyphenyl)sulfonyl]-2,3-dihydro-3-(2-methoxyphenyl)-2-oxo-1H-indol-3-yl]-4-hydroxy-N,N-dimethyl-, (2S,4R)-
• (2S,4R)-1-[(3R)-5-Chloro-1-[(2,4-dimethoxyphenyl)sulfonyl]-2,3-dihydro-3-(2-methoxyphenyl)-2-oxo-1H-indol-3-yl]-4-hydroxy-N,N-dimethyl-2-pyrrolidinecarboxamide
• Nelivaptan
• SSR 149415 - Nelivaptan
• (2S,4R)-1-[(R)-5-CHLORO-1-(2,4-DIMETHOXY-BENZENESULFONYL)-3-(2-METHOXY-PHENYL)-2-OXO-2,3-DIHYDRO-1H-INDOL-3-YL]-4-HYDROXY-PYRROLIDINE-2-CARBOXYLIC ACID DIMETHYLAMIDE
• (2S,4R)-1-[(3R)-5-chloro-1-(2,4-dimethoxyphenyl)sulfonyl-3-(2-methoxyphenyl)-2-oxoindol-3-yl]-4-hydroxy-N,N-dimethylpyrrolidine-2-carboxamide
• Nelivaptan(SSR-149,415)

Nelivaptan

CAS: 439687-69-1

Nelivaptan (SR 149415) is a vasopressin V1b receptor antagonist that can eliminate CHS-induced GE damage.Cost-effective and quality-assured.

Formula: C₃₀H₃₂ClN₃O₈S

Purezza: 98.46% - 99.89%

Colore e forma: Solid

Peso molecolare: 630.11

Ref: TM-T28153

Nelivaptan

CAS: 439687-69-1

Nelivaptan

Purezza: ≥95%

Peso molecolare: 630.11g/mol

Ref: 54-BUP07358

SSR 149415

Prodotto controllato

CAS: 439687-69-1

Formula: C₃₀H₃₂ClN₃O₈S

Colore e forma: Neat

Peso molecolare: 630.108

Ref: TR-S684528

SSR 149415

CAS: 439687-69-1

SSR 149415 is an orally active small molecule that inhibits the activity of receptor tyrosine kinases (RTKs) and can be used to treat autoimmune diseases. SSR 149415 has been shown to inhibit the expression of osteogenic genes in cells. It has also been shown to inhibit the proliferation of prostate cancer cells by binding to the RTKs and inhibiting their downstream signaling pathways. The molecule has been shown to have a high affinity for asymmetric synthesis, which makes it more stable than other molecules. SSR 149415 has been found to bind specifically with polymorphic regions on a number of different proteins, which may make it useful for diagnostic purposes.
SSR 149415 was shown to block dopamine release from striatal neurons in cell culture studies, indicating that this drug may be useful in treating Parkinson’s disease.

Formula: C₃₀H₃₂ClN₃O₈S

Purezza: Min. 95%

Peso molecolare: 630.1 g/mol

Ref: 3D-PSA68769