CAS 444-29-1

1-Iodo-2-(trifluorometil)benzene

Descrizione:

1-Iodo-2-(trifluorometil)benzene, con il numero CAS 444-29-1, è un composto aromatico caratterizzato dalla presenza di un atomo di iodio e di un gruppo trifluorometile (-CF3) attaccato a un anello di benzene. Questo composto è tipicamente un liquido incolore o giallo pallido con un odore distintivo. È noto per la sua densità relativamente alta e bassa solubilità in acqua, rendendolo più solubile nei solventi organici. La presenza del gruppo trifluorometile conferisce proprietà elettroniche uniche, aumentando la sua reattività in varie reazioni chimiche, in particolare nella sostituzione nucleofila e nella sostituzione aromatica elettrofila. Inoltre, l'atomo di iodio può fungere da gruppo uscente nelle reazioni, facilitando la sintesi di altri composti. A causa della sua natura alogenata, 1-Iodo-2-(trifluorometil)benzene può mostrare attività biologica ed è di interesse nella chimica medicinale e nella scienza dei materiali. La corretta manipolazione e conservazione sono essenziali, poiché può comportare rischi per la salute e per l'ambiente.

Formula: C₇H₄F₃I

InChI: InChI=1/C7H4F3I/c8-7(9,10)5-3-1-2-4-6(5)11/h1-4H

InChI key: InChIKey=IGZGUYVVBABKOY-UHFFFAOYSA-N

SMILES: C(F)(F)(F)C1=C(I)C=CC=C1

Sinonimi:

• .alpha.,.alpha.,.alpha.-Trifluoro-o-iodo toluene
• 1-Iod-2-(trifluormethyl)benzol
• 1-Iodo-2-(trifluoromethyl)benzene
• 1-Trifluoromethyl-2-iodobenzene
• 2-(Trifluoromethyl)iodobenzene
• 2-Iodo-1-trifluoromethylbenzene
• 2-Iodobenzotrifluoride
• 2-Trifluoromethylphenyl iodide
• Benzene, 1-iodo-2- (trifluoromethyl)-
• NSC 88291
• Toluene, alpha,alpha,alpha-trifluoro-o-iodo-
• Toluene, α,α,α-trifluoro-o-iodo-
• alpha,alpha,alpha-Trifluoro-2-iodotoluene
• o-(Trifluoromethyl)iodobenzene
• o-Iodobenzotrifluoride
• o-Trifluoromethyliodobenzene
• α,α,α-Trifluoro-o-iodotoluene
• 2-(Trifluoromethyl)iodobenzene, 2-Iodo-α,α,α-trifluorotoluene
• 2-Trifluoromethyliodobenzene
• 2-Iodobenztrifluoride
• 2-Iodobenzotrifluoride (stabilized with Copper chip)
• 2-IODOBENZOTRIFLUORIDE 99%
• alpha,alpha,alpha-Trifluoro-o-iodotoluene
• o-Iodo-alpha,alpha,alpha-trifluorotoluene
• 2-Iodobenzotrifluoride,99%
• 1-iodo-2-(trifluoromethyl)-benzen
• 2-IODO-ALPHA,ALPHA,ALPHA-TRIFLUOROTOLUENE
• O-IODINE TRIFLUORO TOLUENE

2-Iodobenzotrifluoride (stabilized with Copper chip)

CAS: 444-29-1

Formula: C₇H₄F₃I

Purezza: >98.0%(GC)

Colore e forma: Colorless to Light orange to Yellow clear liquid

Peso molecolare: 272.01

Ref: 3B-I0383

2-Iodobenzotrifluoride, 99%

CAS: 444-29-1

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Sci

Formula: C₇H₄F₃I

Purezza: 99%

Colore e forma: Liquid, Clear colorless to yellow or pale green

Peso molecolare: 272.01

Ref: 02-A15698

2-Iodobenzotrifluoride

CAS: 444-29-1

Formula: C₇H₄F₃I

Purezza: 98%

Colore e forma: Liquid

Peso molecolare: 272.0063

Ref: IN-DA0039E1

2-Iodobenzotrifluoride

CAS: 444-29-1

2-Iodobenzotrifluoride

Formula: C₇H₄F₃I

Purezza: 98%

Colore e forma: colourless to light yellow liquid

Peso molecolare: 272.01g/mol

Ref: 54-PC4890

2-Iodobenzotrifluoride

CAS: 444-29-1

2-Iodobenzotrifluoride is a chemical compound that inhibits protein synthesis by binding to the aryl boronic acid groups of proteins. This compound also has anti-inflammatory properties and can be used as a control agent for inflammatory diseases. 2-Iodobenzotrifluoride is soluble in hydrocarbon solvents and reacts with sodium ions to produce sodium-dependent glucose, which can be used as an energy source for cells. The trifluoromethyl group of 2-iodobenzotrifluoride binds to the amino acids serine and histidine, inhibiting their activity. It also inhibits other enzymes such as cholesteryl ester transfer protein and carbonic anhydrase, which are involved in the production of cholesterol.
2-Iodobenzotrifluoride is also able to inhibit nucleophilic groups such as cysteine thiols (SH) and glut

Formula: C₇H₄F₃I

Purezza: Min. 95%

Colore e forma: Clear Liquid

Peso molecolare: 272.01 g/mol

Ref: 3D-FI37781

2-Iodobenzotrifluoride

CAS: 444-29-1

Formula: C₇H₄F₃I

Purezza: 98%

Colore e forma: Liquid

Peso molecolare: 272.009

Ref: 10-F001194

2-Iodobenzotrifluoride

Prodotto controllato

CAS: 444-29-1

Applications 2-Iodobenzotrifluoride acts as a reagent in the preparation, cyclooxygenase-1 inhibitory activity, and docking studies of aminoalkoxyphenylbenzamides. Prepartion and SAR of tricyclic 4,4-dimethyl-3,4-dihydrochromeno[3,4-d]imidazole derivatives as microsomal prostaglandin E2 synthase-1 (mPGES-1) inhibitors.
References Fukai, R., et al.: ChemMedChem, 6, 550 (2011); Muthukaman, N., et al.: Bioorg. Med. Chem. Lett., 27, 2594 (2017)

Formula: C₇H₄F₃I

Colore e forma: Neat

Peso molecolare: 272.01

Ref: TR-I685630