CAS 446-72-0

Genisteina

Descrizione:

Genisteina è un isoflavone che si trova naturalmente, principalmente nella soia e in altre leguminose. Appartiene alla classe dei fitoestrogeni, che sono composti di origine vegetale che possono imitare gli estrogeni nel corpo. Genisteina ha una formula molecolare di C15H10O5 e un peso molecolare di circa 270,24 g/mol. Questo composto presenta una varietà di attività biologiche, comprese proprietà antiossidanti, anti-infiammatorie e potenziali anticancerogene. Si sa che Genisteina interagisce con i recettori degli estrogeni, il che può influenzare la crescita e la differenziazione cellulare. Inoltre, è stato studiato per il suo potenziale ruolo nella riduzione del rischio di tumori correlati agli ormoni, come il cancro al seno e alla prostata. Genisteina è anche riconosciuto per la sua capacità di modulare varie vie di segnalazione, comprese quelle coinvolte nella regolazione del ciclo cellulare e nell'apoptosi. La sua solubilità è generalmente maggiore nei solventi organici rispetto all'acqua, ed è spesso utilizzato in integratori alimentari e alimenti funzionali grazie alle sue proprietà benefiche per la salute. In generale, Genisteina è un composto di grande interesse sia nella scienza nutrizionale che nella farmacologia.

Formula: C₁₅H₁₀O₅

InChI: InChI=1/C15H10O5/c16-9-3-1-8(2-4-9)11-7-20-13-6-10(17)5-12(18)14(13)15(11)19/h1-7,16-18H

InChI key: InChIKey=TZBJGXHYKVUXJN-UHFFFAOYSA-N

SMILES: O=C1C=2C(OC=C1C3=CC=C(O)C=C3)=CC(O)=CC2O

Sinonimi:

• 4',5,7-Trihydroxyisoflavone
• 4′,5,7-Trihydroxyisoflavone
• 5,7,4'-Trihydroxyisoflavone
• 5,7-Dihidroxi-3-(4-Hidroxifenil)-4-Benzopirona
• 5,7-Dihydroxy-3-(4-hydroxyphenyl)-4-benzopyron
• 5,7-Dihydroxy-3-(4-hydroxyphenyl)-4-benzopyrone
• 5,7-Dihydroxy-3-(4-hydroxyphenyl)-4H-1-benzopyran-4-one
• 5,7-Dihydroxy-3-(4-hydroxyphenyl)-4H-chromen-4-one
• Baichanin A
• Bio 300
• Bonistein
• Climagen F
• Csu 1999
• Fw 635I-2
• GeniVida
• Genistein
• Genisteol
• Genisterin
• Genistin aglycone
• Isoflavone, 4',5,7-trihydroxy-
• Isoflavone, 4′,5,7-trihydroxy-
• Npi 031L
• Nsc 36586
• Prunetol
• Sipi 807-1
• Sophoricol
• 4H-1-Benzopyran-4-one, 5,7-dihydroxy-3-(4-hydroxyphenyl)-
• C.I. 75610
• Natural Genistein
• genistein(synthetic)
• Genistein98%,99%
• AKOS NCG1-0029
• GENISTEIN FROM SOYBEAN 98%(HPLC)
• 5,7-DIHYDROXY-3-(4-HYDROXY-PHENYL)-CHROMEN-4-ONE
• differenola
• 4’,5,7-trihydroxy-isoflavon
• GENISTEIN FROM GLYCINE MAX (SOYBEAN)

Genistein

CAS: 446-72-0

Formula: C₁₅H₁₀O₅

Purezza: >98.0%(HPLC)

Colore e forma: White to Light yellow to Light orange powder to crystal

Peso molecolare: 270.24

Ref: 3B-G0272

4',5,7-Trihydroxyisoflavone, 99+%

CAS: 446-72-0

Inhibitor of tyrosine protein kinase

Formula: C₁₅H₁₀O₅

Purezza: 99+%

Colore e forma: Off-white to pale brown, Powder

Peso molecolare: 270.24

Ref: 02-J63241

Genistein

CAS: 446-72-0

Genistein analytical standard provided with w/w absolute assay, to be used for quantitative titration.

Formula: C₁₅H₁₀O₅

Purezza: (HPLC) ≥99%

Colore e forma: Powder

Peso molecolare: 270.24

Ref: 11-1372S

Genistein

CAS: 446-72-0

Aromatic heterocyclic pesticides with oxygen hetero-atom(s) only, nesoi

Formula: C₁₅H₁₀O₅

Colore e forma: White Beige Brown Powder

Peso molecolare: 270.05282

Ref: 45-1288816

4H-1-Benzopyran-4-one, 5,7-dihydroxy-3-(4-hydroxyphenyl)-

CAS: 446-72-0

Formula: C₁₅H₁₀O₅

Purezza: 97%

Colore e forma: Solid

Peso molecolare: 270.2369

Ref: IN-DA00I8G3

Genistein

CAS: 446-72-0

Formula: C₁₅H₁₀O₅

Purezza: (HPLC) ≥ 98.0%

Colore e forma: White, off-white, light yellow or grey-beige powder

Peso molecolare: 270.24

Ref: 7W-GP7710

Genistein

CAS: 446-72-0

Genistein

Purezza: ≥98%

Peso molecolare: 270.24g/mol

Ref: 54-BUP14853

Genistein

CAS: 446-72-0

Formula: C₁₅H₁₀O₅

Colore e forma: Neat

Peso molecolare: 270.24

Ref: 04-C13999800

Genistein

Prodotto controllato

CAS: 446-72-0

Formula: C₁₅H₁₀O₅

Colore e forma: Neat

Peso molecolare: 270.24

Ref: 86-MM0748.00

Genistein

CAS: 446-72-0

Genistein, the major phytoestrogen in soy, is linked to diminished female reproductive performance and to cancer chemoprevention and decreased adipose deposition; genistein-induces hypermethylation persisted into adulthood, decreases ectopic Agouti expression and protecting offspring from obesity, suggests that in utero dietary genistein affects gene expression and alters susceptibility to obesity in adulthood by permanently altering the epigenome.

Formula: C₁₅H₁₀O₅

Purezza: 95%~99%

Colore e forma: Yellow powder

Peso molecolare: 270.24

Ref: BP-BP0634

Genistein

CAS: 446-72-0

Formula: C₁₅H₁₀O₅

Peso molecolare: 270.24

Ref: 4Z-G-033

Genistein

CAS: 446-72-0

Genistein

Purezza: >98%

Colore e forma: Powder

Peso molecolare: 270.24g/mol

Ref: 54-BIMB2006

Genistein

CAS: 446-72-0

Genistein (NPI 031L) is a natural soy isoflavone, a multi-targeted tyrosine kinase inhibitor. Genistein has antitumor effects. Cost effective and quality assured.

Formula: C₁₅H₁₀O₅

Purezza: 98.22% - 99.64%

Colore e forma: Rectangular Or Six-Sided Rods From 60% Alcohol Dendritic Needles From Ether Solid

Peso molecolare: 270.24

Ref: TM-T1737

Genistein

CAS: 446-72-0

Oxygen-heterocyclic compound

Formula: C₁₅H₁₀O₅

Purezza: ≥ 95.0 % (HPLC)

Colore e forma: Powder

Peso molecolare: 270.24

Ref: 5G-89199

Genistein

Prodotto controllato

CAS: 446-72-0

Stability Light Sensitive
Applications Exhibits specific inhibitory activity against tyrosine kinases,including autophosphorylation of epidermal growth factor receptor kinase (IC50 - 2.6uM). Also inhibits other protein kinases through competitive inhibition of ATP. Inhibits tumor cell proliferation and induces tumor cell differentiation. Produces cell-cycle arrest and apoptosis in Jurat T-leukemia cells. However, it prevents anti-CD3 monoclonal antibody-induced thymic apoptosis. Genistein also inhibits topoisomerase II activity in vitro. Genistein has also been shown to inhibit the action of GABA on recombinant GABAA receptors 2. uv(max)ethanol: 262.5 nm (e= 138). moderately sol. in hot alcohol
References Akiyama, T., et al.: J. Biol. Chem., 262, 5592 (1987), O'Dell, T.J., et al.: Nature, 353, 588 (1991), Aharonovits, O., et al.: Biochim Biophys. Acta, 1112, 181 (1992), Platanias, L.C., et al.: J. Biol. Chem., 267, 24053 (1992), Yoshida, H., et al.: Biochim. Biophys. Acta, 1137, 321 (1992), Uckun, F.M., et al.: Science, 267, 886 (1995), Merck Index 12th ed. 4395, Huang, R.Q.; Fang, M.J.; Dillon, G.H., Mol. Brain Res. 67: 177-183 (1999)

Formula: C₁₅H₁₀O₅

Colore e forma: Light Yellow

Peso molecolare: 270.24

Ref: TR-G350000

Genistein

CAS: 446-72-0

Genistein is a naturally occurring isoflavone, which is derived primarily from soy products and other legumes. Its chemical structure allows it to mimic the function of 17-beta-estradiol, a form of estrogen, by binding to estrogen receptors. This selective binding primarily targets estrogen receptor beta, leading to a range of biological effects. Moreover, Genistein exhibits antioxidant properties by scavenging free radicals and inhibiting oxidative stress.

Formula: C₁₅H₁₀O₅

Purezza: Min. 95%

Colore e forma: White Powder

Peso molecolare: 270.24 g/mol

Ref: 3D-FG09961

Genistein

CAS: 446-72-0

M01798 - Genistein

Formula: C₁₅H₁₀O₅

Purezza: 97%

Colore e forma: Solid, Light yellow powder

Peso molecolare: 270.24

Ref: 10-M01798